SYNAPSE Blend (Semax / Selank / MOTS-c / Tesamorelin)
Cognition + metabolic blend
All-in monthly price
No membership fee · this is the full price · free shipping · avg 4-week supply
Add in-depth bloodwork
Optional — add a physician-reviewed at-home blood panel to your plan.
Your sex-hormone baseline plus the safety markers that matter on therapy — blood counts, liver and kidney function — from one painless upper-arm device. Matched to your sex (PSA for men; progesterone & FSH for women). No needle, no clinic, physician-reviewed.
This treatment requires licensed provider review and approval. Treatment is not guaranteed. If prescribed, medication is fulfilled by a licensed U.S. pharmacy where permitted by law. Compounded medications are not FDA-approved or FDA-cleared.
Reviewed by Dr. Gene, MD · Board-certified Family Medicine
Every Pepti prescription is reviewed by a licensed U.S. physician before it's dispensed — and only provided if clinically appropriate.
SYNAPSE Blend (Semax / Selank / MOTS-c / Tesamorelin)
SYNAPSE pairs Semax and Selank, two peptides studied for focus and calm, with MOTS-c for cellular energy and tesamorelin for the body's own growth hormone. A brain-and-body blend for adults who want sharper thinking and more physical energy. Compounded; not FDA-approved.
About a 4-week supply supply at the standard prescribed dose — your physician confirms exact dosing.
A licensed US physician reviews your intake and prescribes when appropriate.
Compounded fresh at a US pharmacy and shipped cold-chain to your door.
Every order ships free — medication, physician care and refills, one all-in price.
Amounts shown are per unit. Compounded fresh at a US FDA-registered pharmacy.
Every batch independently tested
Every medication batch dispensed through Pepti is independently tested by a qualified third-party laboratory for applicable quality and safety standards before the pharmacy releases it. Batches are tested to the same standard used by 503B outsourcing facilities.
Confirms the finished preparation is free of viable microorganisms.
Screens for endotoxins that can cause fever or inflammatory reactions.
Verifies the labeled concentration of the active peptide is what is in the vial.
- Lot 102626-CLA
Tested 2026-10-28 · Biolink Life Sciences Carolinas
Sterility
Sterile
Endotoxin
<2 EU/mL
Potency
99.7%
- Lot 101926-CLA
Tested 2026-10-21 · Biolink Life Sciences Carolinas
Sterility
Sterile
Endotoxin
<2 EU/mL
Potency
99.3%
- Lot 101226-CLA
Tested 2026-10-14 · Biolink Life Sciences Carolinas
Sterility
Sterile
Endotoxin
<2 EU/mL
Potency
99.3%
How SYNAPSE Blend is prescribed.
- Adults who feel mentally foggy and physically flat at the same time
- Professionals who want sharper focus without a stimulant
- People who want a brain peptide and a body peptide in one nightly injection
- Anyone whose energy and concentration dropped together
Your physician decides whether SYNAPSE Blend is appropriate for you after reviewing your intake and labs.
Inject 0.25 mL (25 units) subcutaneously once daily Monday through Friday.
- Licensed physician review of your intake, history, and labs
- Medication compounded to your prescription by a PCAB-accredited, FDA-registered pharmacy
- Every batch independently tested before release
- Sterile syringes and alcohol prep pads for injectables
- Tracked delivery to your door, refills on schedule
- Message your physician anytime; dose changes without an appointment
- Store refrigerated (36–46°F / 2–8°C) at all times, including before first use.
- One vial is your monthly supply. A fresh vial ships every 28 days on your refill schedule, so you're always well inside the beyond-use date on your label.
- Protect from light. Wipe the stopper with an alcohol pad before every draw.
- Dispose of syringes in the sharps container per the included instructions.
A typical course of SYNAPSE Blend.
Everything published
about SYNAPSE Blend.
How it is described to work, pathway by pathway. What the research shows and what it does not. Where it stands with the FDA, dated and sourced.
Read the referencepeer-reviewed, each verified on PubMed
mechanism, evidence, dosing, safety, FAQ
2026 · checked against fda.gov, not memory
How SYNAPSE Blend works, and what the research shows.
Semax is studied for attention and memory through a brain growth factor; Selank for calm through the brain's own calming signal.
MOTS-c is studied for switching on the cell's energy sensor.
Tesamorelin prompts the pituitary gland to release growth hormone overnight.
No clinical trial has studied this exact combination.
The evidence is for each peptide on its own, and your physician weighs that when deciding whether the blend fits you.
References
- Dolotov OV, Karpenko EA, Inozemtseva LS et al.. Semax, an analog of ACTH(4-10) with cognitive effects, regulates BDNF and trkB expression in the rat hippocampus · Brain Res (2006) · PMID 16996037
- Lee C, Zeng J, Drew BG et al.. The mitochondrial-derived peptide MOTS-c promotes metabolic homeostasis and reduces obesity and insulin resistance · Cell Metab (2015) · PMID 25738459
- Falutz J, Allas S, Blot K et al.. Metabolic effects of a growth hormone-releasing factor in patients with HIV · N Engl J Med (2007) · PMID 18057338
- Friedman SD, Baker LD, Borson S et al.. Growth hormone-releasing hormone effects on brain γ-aminobutyric acid levels in mild cognitive impairment and healthy aging · JAMA Neurol (2013) · PMID 23689947
- Baker LD, Barsness SM, Borson S et al.. Effects of growth hormone-releasing hormone on cognitive function in adults with mild cognitive impairment and healthy older adults: results of a controlled trial · Arch Neurol (2012) · PMID 22869065
Citations are provided for educational purposes. They do not constitute medical advice. Always discuss any peptide protocol with your prescribing physician.
Important safety information
+
Possible side effects
Do not use if you have
If you experience severe side effects, call 911 or go to your nearest emergency room.
5 mL multi-dose vial, Semax 1 mg/mL + Selank 1 mg/mL + MOTS-c 2 mg/mL + Tesamorelin 2 mg/mL (5 mg Semax / 5 mg Selank / 10 mg MOTS-c / 10 mg Tesamorelin per vial)
Frequently asked
about SYNAPSE Blend (Semax / Selank / MOTS-c / Tesamorelin).
SYNAPSE pairs Semax and Selank, two peptides studied for focus and calm, with MOTS-c for cellular energy and tesamorelin for the body's own growth hormone. A brain-and-body blend for adults who want sharper thinking and more physical energy. Compounded; not FDA-approved. SYNAPSE Blend (Semax / Selank / MOTS-c / Tesamorelin) is prescription-only at Pepti: a licensed physician reviews your assessment and, if appropriate, prescribes it to be compounded by a state-licensed, FDA-registered pharmacy.
SYNAPSE Blend (Semax / Selank / MOTS-c / Tesamorelin) is $279 per month at Pepti. That is all-in: medication, physician review and ongoing care, shipping, and messaging. No membership, consult, or visit fees, and the price is the same in every state.
SYNAPSE Blend (Semax / Selank / MOTS-c / Tesamorelin) is commonly prescribed for: Adults who feel mentally foggy and physically flat at the same time; Professionals who want sharper focus without a stimulant; People who want a brain peptide and a body peptide in one nightly injection; Anyone whose energy and concentration dropped together. Whether it is appropriate for you is decided by the reviewing physician from your history, medications, and labs where required.
Yes. SYNAPSE Blend (Semax / Selank / MOTS-c / Tesamorelin) is prescription-only. The free online assessment takes about five minutes, a physician licensed in your state reviews it within 4 hours, and if approved the prescription goes to the pharmacy. If not approved, the medication charge is refunded.
No. SYNAPSE Blend (Semax / Selank / MOTS-c / Tesamorelin) can be prescribed from the assessment alone. If your physician wants labs for your care, they'll ask through your account; upload a recent lab report from any lab at no charge, or order Pepti's at-home panel.
SYNAPSE Blend (Semax / Selank / MOTS-c / Tesamorelin) is a subcutaneous injection into the abdomen or thigh with a small insulin syringe. Your kit ships with sterile syringes and alcohol prep pads, and the exact dose and schedule are printed on the pharmacy label. Dosing videos are in your account.
33 more questions about Pepti, answered.Show fewer
One vial is your monthly supply at the dose your physician prescribes. A fresh vial ships about every 28 days, and the date moves if your physician changes your dose. Store it as the pharmacy label directs, refrigerated.
Once per fill, $279 each time, when the next vial ships. It renews until you cancel, which you can do anytime from your account with no cancellation fee.
The compounded SYNAPSE Blend (Semax / Selank / MOTS-c / Tesamorelin) with sterile syringes and alcohol prep pads, free tracked shipping in an unbranded box with insulated packaging, the physician review, ongoing physician care and dose adjustments, and unlimited messaging.
Reported side effects of SYNAPSE Blend (Semax / Selank / MOTS-c / Tesamorelin) are usually mild: mild redness or swelling at injection site; temporary fatigue or headache; mild nausea (uncommon). The physician screens your history, medications, and allergies before prescribing, the medication-specific consent lists the known risks, and you can message your physician about anything you notice. Seek emergency care for severe symptoms.
Response varies by person, goal, and dose, and SYNAPSE Blend (Semax / Selank / MOTS-c / Tesamorelin) is prescribed for ongoing use rather than a short trial. Your physician sets expectations at approval, tracks how you respond through your account, and adjusts the dose without an appointment.
Yes. Request it from your account or the app; your physician approves or declines. If approved you pay for the additional medication at the pharmacy's cost and the new dose applies to your next shipment.
Yes. Add SYNAPSE Blend (Semax / Selank / MOTS-c / Tesamorelin) to a plan with another treatment and both go through one assessment and one physician review, shipping together on one schedule. Each keeps its own catalog price. The physician reviews the combination and can adjust it.
No. Compounded SYNAPSE Blend (Semax / Selank / MOTS-c / Tesamorelin) is not FDA-approved. It is prepared to your physician's prescription by a state-licensed, FDA-registered 503A pharmacy and every batch is independently tested before release.
Yes, when prescribed by a licensed physician and dispensed by a licensed pharmacy, which is how Pepti provides it in every state it serves. Research-use-only SYNAPSE Blend (Semax / Selank / MOTS-c / Tesamorelin) sold without a prescription is labeled not for human use and is a different product.
Semax is studied for attention and memory through a brain growth factor; Selank for calm through the brain's own calming signal. At Pepti it is prescribed to support focus and memory from semax, calm from selank, cellular energy from mots-c, growth-hormone release from tesamorelin. Individual response varies, and your physician sets expectations at approval.
Semax is studied for attention and memory through a brain growth factor; Selank for calm through the brain's own calming signal. MOTS-c is studied for switching on the cell's energy sensor. Tesamorelin prompts the pituitary gland to release growth hormone overnight. Compounded SYNAPSE Blend (Semax / Selank / MOTS-c / Tesamorelin) is not FDA-approved; it is prescribed off-label by a licensed physician after reviewing your assessment.
SYNAPSE Blend (Semax / Selank / MOTS-c / Tesamorelin) is prescribed for focus and memory from semax, calm from selank, cellular energy from mots-c, growth-hormone release from tesamorelin. It is commonly requested by adults who feel mentally foggy and physically flat at the same time; Professionals who want sharper focus without a stimulant; people who want a brain peptide and a body peptide in one nightly injection; Anyone whose energy and concentration dropped together. Whether it is appropriate for you is the reviewing physician's decision.
SYNAPSE Blend (Semax / Selank / MOTS-c / Tesamorelin) is studied for focus and memory from semax, calm from selank, cellular energy from mots-c, growth-hormone release from tesamorelin. Those are the goals it is prescribed to support at Pepti; results vary by person, dose, and consistency, and no outcome is guaranteed. Your physician tracks how you respond through your account.
No clinical trial has studied this exact combination. The evidence is for each peptide on its own, and your physician weighs that when deciding whether the blend fits you. References are listed on this page.
SYNAPSE Blend (Semax / Selank / MOTS-c / Tesamorelin) is generally not prescribed with: active cancer or history of cancer (unless approved by oncologist); pregnancy or breastfeeding; severe kidney or liver disease; known allergy to the peptide or excipients. The physician screens for these in your intake, and anything that rules SYNAPSE Blend (Semax / Selank / MOTS-c / Tesamorelin) out means it is not prescribed and is refunded.
At Pepti. Complete the free assessment, a physician licensed in your state reviews it within 4 hours, and if appropriate SYNAPSE Blend (Semax / Selank / MOTS-c / Tesamorelin) is compounded by a state-licensed, FDA-registered pharmacy and shipped free to your door for $279 per month, all-in. Not prescribed means refunded.
Injectable vial: 5 mL, containing 5 mg Semax + 5 mg Selank + 10 mg MOTS-c + 10 mg Tesamorelin. One vial is your monthly supply at the prescribed dose, and a fresh one ships about every 28 days.
Not currently. SYNAPSE Blend (Semax / Selank / MOTS-c / Tesamorelin) ships as a multi-dose vial with sterile syringes and prep pads. The pepti Pen is available for 10 other treatments.
$279 per month covers the compounded SYNAPSE Blend (Semax / Selank / MOTS-c / Tesamorelin), the physician review, ongoing physician care including dose adjustments and refill review, unlimited messaging, and free tracked shipping. There is no membership, consult, visit, or refill fee; the only separate charges are optional at-home lab panels and a physician-approved dose increase billed at pharmacy cost.
Yes. SYNAPSE Blend (Semax / Selank / MOTS-c / Tesamorelin) is on Pepti's live catalog, which lists only treatments a partner pharmacy can compound and ship today. If a physician prescribes it, it ships; if it ever cannot be dispensed, the charge is refunded.
SYNAPSE Blend (Semax / Selank / MOTS-c / Tesamorelin) ships to 50 states, free and tracked, in insulated unbranded packaging. Eligibility is confirmed during the assessment from your shipping address.
$279 per month at Pepti. That includes the compounded SYNAPSE Blend (Semax / Selank / MOTS-c / Tesamorelin), the physician review and ongoing care, free tracked shipping, and messaging, with no membership, consult, or visit fee. The price is the same in every state and every refill is the same price.
Pepti supplies SYNAPSE Blend (Semax / Selank / MOTS-c / Tesamorelin) as a monthly injectable vial with syringes and prep pads included, one vial per month at $279, prescribed by a licensed physician after a free online assessment and shipped free from a state-licensed, FDA-registered pharmacy in insulated packaging.
Yes. Pepti prescribes SYNAPSE Blend (Semax / Selank / MOTS-c / Tesamorelin) online in 50 states after a free assessment reviewed by a physician licensed in your state. It is compounded by an FDA-registered pharmacy and shipped free, $279 per month all-in. Not prescribed means refunded.
Yes. At Pepti the entire process is telehealth: a five-minute online assessment, physician review within 4 hours, then SYNAPSE Blend (Semax / Selank / MOTS-c / Tesamorelin) ships from the pharmacy. No clinic visit and no video appointment in most cases. $279 per month, all-in.
Yes, for the real thing. SYNAPSE Blend (Semax / Selank / MOTS-c / Tesamorelin) sold without a prescription is research-use-only product labeled not for human use, with no physician, no pharmacy, and no verified testing. Pepti's SYNAPSE Blend (Semax / Selank / MOTS-c / Tesamorelin) is physician-prescribed, pharmacy-compounded, batch-tested, and $279 per month including the physician and shipping.
Pepti does, in 50 states, with named board-certified physicians, a state-licensed FDA-registered compounding pharmacy, independent batch testing, and one published all-in price of $279 per month with no membership or consult fee. Refunded if the physician does not prescribe.
It is legal to be prescribed SYNAPSE Blend (Semax / Selank / MOTS-c / Tesamorelin) online by a licensed physician and have it dispensed by a licensed pharmacy, which is how Pepti provides it. Buying it as a research chemical without a prescription is a different product and is not for human use. Compounded SYNAPSE Blend (Semax / Selank / MOTS-c / Tesamorelin) is not FDA-approved.
$279 per month at Pepti, including the medication, the physician, and shipping. Refills are the same price and there is no membership fee.
Yes. Pepti has no clinics: the assessment, physician review, messaging, dose changes, and refills all happen online, and SYNAPSE Blend (Semax / Selank / MOTS-c / Tesamorelin) ships free from the pharmacy to your door in 50 states.
Start the free assessment at hellopepti.com, choose SYNAPSE Blend (Semax / Selank / MOTS-c / Tesamorelin), and answer the health questions. A physician licensed in your state reviews it within 4 hours. If approved, SYNAPSE Blend (Semax / Selank / MOTS-c / Tesamorelin) ships within 1-3 business days and arrives in 1-3 more; if not, the $279 is refunded.
No. SYNAPSE Blend (Semax / Selank / MOTS-c / Tesamorelin) can be prescribed from the assessment alone at Pepti. If your physician wants labs for your care, they'll ask through your account; upload a lab report from any lab, or order a Pepti at-home panel from $129.
Pepti ships SYNAPSE Blend (Semax / Selank / MOTS-c / Tesamorelin) to 50 states, free and tracked, refrigerated in insulated packaging, directly from the pharmacy. Delivery is 1-3 business days after the pharmacy compounds it.
Questions people ask
about SYNAPSE Blend (Semax / Selank / MOTS-c / Tesamorelin).
- SYNAPSE Blend (Semax / Selank / MOTS-c / Tesamorelin): What It Is, Where to Get It Prescribed, and What It CostsSYNAPSE Blend (Semax / Selank / MOTS-c / Tesamorelin) — 5 mL multi-dose vial, Semax 1 mg/mL + Selank 1 mg/mL + MOTS-c 2 mg/mL + Tesamorelin 2 mg/mL (5 mg Semax / 5 mg Selank / 10 mg MOTS-c / 10 mg Tesamorelin per vial). Specification, mechanism, dosing, formats, state availability and how to get it prescribed.
- Dihexa vs Semax: Mechanism, Evidence, Cost, and Which One FitsDihexa and Semax are both prescribed for memory and focus, but they come from different systems and have very different evidence. A side-by-side of what each is, how each is described to work, the human data, FDA status, dosing, price and who suits which.
- SYNAPSE Blend Dosage: How Pepti Prescribes Semax, Selank, MOTS-c and Tesamorelin in One VialThe SYNAPSE blend dosage Pepti prescribes: 0.25 mL (25 units on a U-100 insulin syringe) under the skin once daily Monday through Friday, 20 doses per vial. Each dose is 0.25 mg Semax, 0.25 mg Selank, 0.5 mg MOTS-c and 0.5 mg tesamorelin. Includes a units, mL and mg chart, how SYNAPSE compares with the single peptides and ELEVATE, timing, what changes the directions, and side effects.
- SYNAPSE Blend Side Effects: Semax, Selank, MOTS-c and Tesamorelin, and What to ReportA practical reference to SYNAPSE blend side effects: injection-site reactions, the fluid-related growth hormone effects and blood sugar caution from tesamorelin, MOTS-c's brief jitteriness, Semax's late-day restlessness, psychiatric medications and stimulants, what needs 911, when to message your care team, and who should not take it.
- SYNAPSE Blend Benefits: What the Research on Semax, Selank, MOTS-c and Tesamorelin Actually ShowsThe benefits claimed for the SYNAPSE blend, one at a time: neurotrophic signalling, stress and anxiety, cellular fuel sensing, visceral fat and cognition in older adults, each tied to the component it comes from and labelled as cell, animal or human research, with an honest strength-of-evidence rating.
- Can You Take SYNAPSE Blend With Tirzepatide or Semaglutide?SYNAPSE and tirzepatide work through unrelated systems and are not a duplication, but no study has tested the pairing. The point to know is glucose: SYNAPSE carries tesamorelin, which can raise blood sugar, and MOTS-c, described in mice around insulin sensitivity, while GLP-1 medications lower it. How the schedules fit, the nausea overlap, and what to tell your physician.
- How Long Does SYNAPSE Blend Take to Work? What Each Component's Studies Measured, and WhenSYNAPSE has never been studied as a blend, so there is no timeline for it. Its components' studies ran from a single dose (Semax brain imaging, rat Selank gene work) to 20 and 26 weeks (tesamorelin cognition and visceral fat trials), in named populations and often by other routes. This page lays out each study's length and endpoint, why none converts into a date for you, and what to track.
- Do You Need a Prescription for SYNAPSE Blend? Is It Legal to Buy Online?Yes: SYNAPSE Blend (Semax / Selank / MOTS-c / Tesamorelin) for injection is a prescription medication in the US. Where each of its four peptides stands with the FDA after the 2026 changes, why tesamorelin sits outside the bulks-list process, what "research use only" means legally, and what a lawful prescription looks like.
- Best Place to Get SYNAPSE Blend Online: How to Choose a Provider, and What Pepti OffersWhere to get SYNAPSE Blend (Semax / Selank / MOTS-c / Tesamorelin) prescribed online: a checklist for choosing a provider, the red flags specific to a "nootropic" peptide blend, and exactly what Pepti's SYNAPSE prescription includes and costs.
- How to Get SYNAPSE Blend Prescribed Online: The Steps, What the Intake Asks, and What ArrivesThe step-by-step route to a SYNAPSE Blend (Semax / Selank / MOTS-c / Tesamorelin) prescription through telehealth: the assessment, the medical intake and what it asks about psychiatric medication, glucose and cancer history, physician review, compounding, refrigerated shipping, refills and cost.
- SYNAPSE Blend for Women: What the Research Has Looked At, and the Pregnancy RuleWhat research has looked at for SYNAPSE's four components in relation to women: no component's human trials reported women separately, MOTS-c's ovariectomised-mouse work, the abdominal fat shift around menopause, why tesamorelin makes pregnancy and breastfeeding a firm exclusion, cancer history, glucose, and how to get SYNAPSE prescribed.
- SYNAPSE Blend for Men: What the Research Has Looked At, and What to Check FirstWhat research has looked at for SYNAPSE's four components in relation to men: tesamorelin's visceral fat trials that enrolled mostly men, a MOTS-c genetic finding in men, no male-specific Semax or Selank data, why SYNAPSE is not a testosterone booster, TRT, stimulants, glucose, tested sport, and how to get it prescribed.
- Is SYNAPSE Blend Banned in Sports? Tesamorelin, MOTS-c and the WADA ListYes. SYNAPSE contains tesamorelin, named under S2.2.4 of the 2026 WADA Prohibited List, and MOTS-c, named under S4.4.1, both prohibited at all times. What the List says about each of the four components, why a prescription or the small amount does not matter, TUEs, detection, the NCAA, workplace drug tests, and where SYNAPSE stands with the FDA.
- Can You Drink Alcohol on SYNAPSE Blend? What Is Known and What Is NotWhether alcohol and SYNAPSE interact: no study has tested it and no interaction is described for any of its four components. The only alcohol research is a 2019 rat study of Selank and alcohol withdrawal. Why Selank's GABA mechanism, tesamorelin's blood sugar effect and sleep are the practical points, what alcohol does on its own during treatment, and what to tell your physician.
- How Much Does SYNAPSE Cost?SYNAPSE cost in 2026: $279 per month all-in at Pepti — compounded medication, physician review, and shipping included. No membership or consult fees.
Read more about SYNAPSE Blend (Semax / Selank / MOTS-c / Tesamorelin).
How to Get SYNAPSE Blend Prescribed Online: The Steps, What the Intake Asks, and What Arrives
The step-by-step route to a SYNAPSE Blend (Semax / Selank / MOTS-c / Tesamorelin) prescription through telehealth: the assessment, the medical intake and what it asks about psychiatric medication, glucose and cancer history, physician review, compounding, refrigerated shipping, refills and cost.
Do You Need a Prescription for SYNAPSE Blend? Is It Legal to Buy Online?
Yes: SYNAPSE Blend (Semax / Selank / MOTS-c / Tesamorelin) for injection is a prescription medication in the US. Where each of its four peptides stands with the FDA after the 2026 changes, why tesamorelin sits outside the bulks-list process, what "research use only" means legally, and what a lawful prescription looks like.
Best Place to Get SYNAPSE Blend Online: How to Choose a Provider, and What Pepti Offers
Where to get SYNAPSE Blend (Semax / Selank / MOTS-c / Tesamorelin) prescribed online: a checklist for choosing a provider, the red flags specific to a "nootropic" peptide blend, and exactly what Pepti's SYNAPSE prescription includes and costs.
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