Pre-filled cartridge + a free reusable injector pen — click-dial dosing, no drawing from a vial. Ships overnight cold.
— All-in monthly price
No membership fee · this is the full price · free shipping · avg 4-week supply
— Add in-depth bloodwork
Optional — add a physician-reviewed at-home blood panel to your plan.
Your sex-hormone baseline plus the safety markers that matter on therapy — blood counts, liver and kidney function — from one painless upper-arm device. Matched to your sex (PSA for men; progesterone & FSH for women). No needle, no clinic, physician-reviewed.
This treatment requires licensed provider review and approval. Treatment is not guaranteed. If prescribed, medication is fulfilled by a licensed U.S. pharmacy where permitted by law. Compounded medications are not FDA-approved or FDA-cleared.
Reviewed
Reviewed by Dr. Gene Lee, MD · Board-certified Family Medicine
Every Pepti prescription is reviewed by a licensed U.S. physician before it's dispensed — and only provided if clinically appropriate.
— About
MOTS-c (Injectable)
A mitochondrial-derived peptide that regulates metabolic homeostasis and cellular energy.
— Benefits
— Supply per fill
About a 4-week supply supply at the standard prescribed dose — your physician confirms exact dosing.
— Physician review
A licensed US physician reviews your intake and prescribes when appropriate.
— FDA-registered pharmacy
Compounded fresh at a US pharmacy and shipped cold-chain to your door.
— Shipping, always
Every order ships free — medication, physician care and refills, one all-in price.
— Formulation
— Quality
Every batch independently tested
Every medication batch dispensed through Pepti is independently tested by a qualified third-party laboratory for applicable quality and safety standards before the pharmacy releases it. Batches are tested to the same standard used by 503B outsourcing facilities.
Sterility
USP <71>Confirms the finished preparation is free of viable microorganisms.
Bacterial endotoxins
USP <85>Screens for endotoxins that can cause fever or inflammatory reactions.
Potency
AssayVerifies the labeled concentration of the active peptide is what is in the vial.
Purity
HPLCChecks the active peptide against impurities and degradation products.
Identity
Mass spectrometryConfirms the peptide in the vial is the correct molecule.
pH
USP <791>Confirms the solution sits within the range specified for injection.
Particulate matter
USP <788>Checks the finished vial for visible and sub-visible particles.
Container closure integrity
USP <1207>Confirms the vial seal holds so sterility is maintained through the beyond-use date.
— Your protocol
How MOTS-c is prescribed.
— Who it's for
- Adults focused on metabolic health, endurance, and insulin sensitivity
- Patients who want a mitochondrial-targeting peptide alongside training
Your physician decides whether MOTS-c is appropriate for you after reviewing your intake and labs.
— Directions & duration
Inject 0.25 mL (25 units) subcutaneously Monday through Friday mornings.
— What's included
- Licensed physician review of your intake, history, and labs
- Medication compounded to your prescription by a PCAB-accredited, FDA-registered pharmacy
- Every batch independently tested before release
- Sterile syringes and alcohol prep pads for injectables
- Tracked delivery to your door, refills on schedule
- Message your physician anytime; dose changes without an appointment
— Storage & handling
- Store refrigerated (36–46°F / 2–8°C) at all times, including before first use.
- One vial is your monthly supply. A fresh vial ships every 28 days on your refill schedule, so you're always well inside the beyond-use date on your label.
- Protect from light. Wipe the stopper with an alcohol pad before every draw.
- Dispose of syringes in the sharps container per the included instructions.
— What to expect
A typical course of MOTS-c.
— The science
How MOTS-c works, and what the research shows.
— How it works
MOTS-c is a peptide encoded within mitochondrial DNA.
It regulates metabolic homeostasis, improves insulin sensitivity, and acts as an exercise mimetic — boosting cellular energy and metabolic flexibility.
— Clinical evidence
MOTS-c was identified as a mitochondrial-derived peptide regulating metabolic homeostasis, where it improved insulin sensitivity and exercise capacity in mice.
Lee et al., Cell Metab 2015Levels rise with exercise in humans, and an analog has entered early-phase human trials for metabolic disease.
Direct human outcome data for MOTS-c itself remains limited — it is prescribed as an investigational metabolic peptide.
Important safety information
+
Possible side effects
Do not use if you have
If you experience severe side effects, call 911 or go to your nearest emergency room.
— Common questions
Frequently asked
about MOTS-c (Injectable).
A mitochondrial-derived peptide that regulates metabolic homeostasis and cellular energy. MOTS-c is prescription-only at Pepti: a licensed physician reviews your assessment and, if appropriate, prescribes it to be compounded by a state-licensed, FDA-registered pharmacy.
MOTS-c is $259 per month at Pepti as a vial, or $339 as a pre-filled pepti Pen. That is all-in: medication, physician review and ongoing care, shipping, and messaging. No membership, consult, or visit fees, and the price is the same in every state.
MOTS-c is commonly prescribed for: Adults focused on metabolic health, endurance, and insulin sensitivity; Patients who want a mitochondrial-targeting peptide alongside training. Whether it is appropriate for you is decided by the reviewing physician from your history, medications, and labs where required.
Yes. MOTS-c is prescription-only. The free online assessment takes about five minutes, a physician licensed in your state reviews it within 24 hours, and if approved the prescription goes to the pharmacy. If not approved, the medication charge is refunded.
No. MOTS-c can be prescribed from the assessment alone. Bloodwork is required only for the GLP-1s and growth-hormone secretagogues, and the intake tells you if a medication on your order needs it.
MOTS-c is a subcutaneous injection into the abdomen or thigh with a small insulin syringe. Your kit ships with sterile syringes and alcohol prep pads, and the exact dose and schedule are printed on the pharmacy label. Dosing videos are in your account. It is also available as a pre-filled pepti Pen for $339.
— More questions33 more questions about Pepti, answered.
One vial is your monthly supply at the dose your physician prescribes. A fresh vial ships about every 28 days, and the date moves if your physician changes your dose. Store it as the pharmacy label directs, refrigerated.
Once per fill, $259 each time, when the next vial ships. It renews until you cancel, which you can do anytime from your account with no cancellation fee.
The compounded MOTS-c with sterile syringes and alcohol prep pads, free tracked shipping in an unbranded box with insulated packaging, the physician review, ongoing physician care and dose adjustments, and unlimited messaging.
Reported side effects of MOTS-c are usually mild: mild redness or swelling at injection site; temporary fatigue or headache; mild nausea (uncommon). The physician screens your history, medications, and allergies before prescribing, the medication-specific consent lists the known risks, and you can message your physician about anything you notice. Seek emergency care for severe symptoms.
Response varies by person, goal, and dose, and MOTS-c is prescribed for ongoing use rather than a short trial. Your physician sets expectations at approval, tracks how you respond through your account, and adjusts the dose without an appointment.
Yes. Request it from your account or the app; your physician approves or declines. If approved you pay for the additional medication at the pharmacy's cost and the new dose applies to your next shipment.
Yes. Add MOTS-c to a plan with another treatment and every medication is 5% off, three are 8% off, and four or more are 10% off, on every refill. The physician reviews the combination and can adjust it.
No. Compounded MOTS-c is not FDA-approved. It is prepared to your physician's prescription by a state-licensed, FDA-registered 503A pharmacy and every batch is independently tested before release.
Yes, when prescribed by a licensed physician and dispensed by a licensed pharmacy, which is how Pepti provides it in every state it serves. Research-use-only MOTS-c sold without a prescription is labeled not for human use and is a different product.
MOTS-c is a peptide encoded within mitochondrial DNA. At Pepti it is prescribed to support mitochondrial health, metabolic regulation, exercise mimetic, longevity. Individual response varies, and your physician sets expectations at approval.
MOTS-c is a peptide encoded within mitochondrial DNA. It regulates metabolic homeostasis, improves insulin sensitivity, and acts as an exercise mimetic — boosting cellular energy and metabolic flexibility. Compounded MOTS-c is not FDA-approved; it is prescribed off-label by a licensed physician after reviewing your assessment.
MOTS-c is prescribed for mitochondrial health, metabolic regulation, exercise mimetic, longevity. It is commonly requested by adults focused on metabolic health, endurance, and insulin sensitivity; patients who want a mitochondrial-targeting peptide alongside training. Whether it is appropriate for you is the reviewing physician's decision.
MOTS-c is studied for mitochondrial health, metabolic regulation, exercise mimetic, longevity. Those are the goals it is prescribed to support at Pepti; results vary by person, dose, and consistency, and no outcome is guaranteed. Your physician tracks how you respond through your account.
MOTS-c was identified as a mitochondrial-derived peptide regulating metabolic homeostasis, where it improved insulin sensitivity and exercise capacity in mice (Lee et al., Cell Metab 2015). Levels rise with exercise in humans, and an analog has entered early-phase human trials for metabolic disease. Direct human outcome data for MOTS-c itself remains limited — it is prescribed as an investigational metabolic peptide. References are listed on this page.
MOTS-c is generally not prescribed with: active cancer or history of cancer (unless approved by oncologist); pregnancy or breastfeeding; severe kidney or liver disease; known allergy to the peptide or excipients. The physician screens for these in your intake, and anything that rules MOTS-c out means it is not prescribed and is refunded.
At Pepti. Complete the free assessment, a physician licensed in your state reviews it within 24 hours, and if appropriate MOTS-c is compounded by a state-licensed, FDA-registered pharmacy and shipped free to your door for $259 per month, all-in. Not prescribed means refunded.
Injectable vial: 5 mL at 2 mg/mL, containing 10 mg MOTS-c. Pepti Pen cartridge: 3 mL cartridge (300 units) at 10 mg/mL, containing 30 mg MOTS-c. One vial is your monthly supply at the prescribed dose, and a fresh one ships about every 28 days.
Yes. MOTS-c is available as a pre-filled pepti Pen cartridge for $339 per month, versus $259 as a vial. Same medication, same pharmacy; the reusable injector is free with your first pen order. Choose the format in the cart or ask your physician.
$259 per month covers the compounded MOTS-c, the physician review, ongoing physician care including dose adjustments and refill review, unlimited messaging, and free tracked shipping. There is no membership, consult, visit, or refill fee; the only separate charges are optional at-home lab panels and a physician-approved dose increase billed at pharmacy cost.
Yes. MOTS-c is on Pepti's live catalog, which lists only treatments a partner pharmacy can compound and ship today. If a physician prescribes it, it ships; if it ever cannot be dispensed, the charge is refunded.
MOTS-c ships to all 50 states and Washington, D.C, free and tracked, in insulated unbranded packaging. Eligibility is confirmed during the assessment from your shipping address.
$259 per month at Pepti as a vial, or $339 as a pepti Pen. That includes the compounded MOTS-c, the physician review and ongoing care, free tracked shipping, and messaging, with no membership, consult, or visit fee. The price is the same in every state and every refill is the same price.
Yes. Pepti offers MOTS-c as a pre-filled pepti Pen cartridge for $339 per month, or as a vial for $259. The reusable injector is included free with your first pen order and tips come with every cartridge. Same medication, same pharmacy, physician-prescribed after a free online assessment.
Yes. Pepti prescribes MOTS-c online in all 50 states and Washington, D.C after a free assessment reviewed by a physician licensed in your state. It is compounded by an FDA-registered pharmacy and shipped free, $259 per month all-in. Not prescribed means refunded.
Yes. At Pepti the entire process is telehealth: a five-minute online assessment, physician review within 24 hours, then MOTS-c ships from the pharmacy. No clinic visit and no video appointment in most cases. $259 per month, all-in.
Yes, for the real thing. MOTS-c sold without a prescription is research-use-only product labeled not for human use, with no physician, no pharmacy, and no verified testing. Pepti's MOTS-c is physician-prescribed, pharmacy-compounded, batch-tested, and $259 per month including the physician and shipping.
Pepti does, in all 50 states and Washington, D.C, with named board-certified physicians, a state-licensed FDA-registered compounding pharmacy, independent batch testing, and one published all-in price of $259 per month with no membership or consult fee. Refunded if the physician does not prescribe.
It is legal to be prescribed MOTS-c online by a licensed physician and have it dispensed by a licensed pharmacy, which is how Pepti provides it. Buying it as a research chemical without a prescription is a different product and is not for human use. Compounded MOTS-c is not FDA-approved.
$259 per month at Pepti, or $339 as a pepti Pen, including the medication, the physician, and shipping. Refills are the same price, there is no membership fee, and stacking it with a second treatment takes 5% off both.
Yes. Pepti has no clinics: the assessment, physician review, messaging, dose changes, and refills all happen online, and MOTS-c ships free from the pharmacy to your door in all 50 states and Washington, D.C.
Start the free assessment at hellopepti.com, choose MOTS-c, and answer the health questions. A physician licensed in your state reviews it within 24 hours. If approved, MOTS-c ships within 1-3 business days and arrives in 1-3 more; if not, the $259 is refunded.
No. MOTS-c can be prescribed from the assessment alone at Pepti. Bloodwork is required only for GLP-1s and growth-hormone secretagogues.
Pepti ships MOTS-c to all 50 states and Washington, D.C, free and tracked, refrigerated in insulated packaging, directly from the pharmacy. Delivery is 1-3 business days after the pharmacy compounds it.
Get started today
Ready to start with MOTS-c (Injectable)?
Free assessment. Licensed physicians. Money-back guarantee if not approved.

— Pharmacy network accreditation
PCAB-accredited pharmacies on every order.
Every fulfillment runs through a PCAB-accredited pharmacy.






