— Your starting dose
New to this medication? Your provider starts you low and steps you up over time.
— All-in monthly price
No membership fee · this is the full price · free shipping · avg 4-week supply
— Add in-depth bloodwork
Optional — add a physician-reviewed at-home blood panel to your plan.
Your sex-hormone baseline plus the safety markers that matter on therapy — blood counts, liver and kidney function — from one painless upper-arm device. Matched to your sex (PSA for men; progesterone & FSH for women). No needle, no clinic, physician-reviewed.
This treatment requires licensed provider review and approval. Treatment is not guaranteed. If prescribed, medication is fulfilled by a licensed U.S. pharmacy where permitted by law. Compounded medications are not FDA-approved or FDA-cleared.
Reviewed
Reviewed by Dr. Gene Lee, MD · Board-certified Family Medicine
Every Pepti prescription is reviewed by a licensed U.S. physician before it's dispensed — and only provided if clinically appropriate.
— About
Semaglutide (Injectable)
GLP-1 receptor agonist prescribed for medical weight management under licensed physician supervision. Compounded; not FDA-approved.
— Benefits
— Supply per fill
About a 4-week supply supply at the standard prescribed dose — your physician confirms exact dosing.
— Physician review
A licensed US physician reviews your intake and prescribes when appropriate.
— FDA-registered pharmacy
Compounded fresh at a US pharmacy and shipped cold-chain to your door.
— Shipping, always
Every order ships free — medication, physician care and refills, one all-in price.
— Formulation
— Quality
Every batch independently tested
Every medication batch dispensed through Pepti is independently tested by a qualified third-party laboratory for applicable quality and safety standards before the pharmacy releases it. Batches are tested to the same standard used by 503B outsourcing facilities.
Sterility
USP <71>Confirms the finished preparation is free of viable microorganisms.
Bacterial endotoxins
USP <85>Screens for endotoxins that can cause fever or inflammatory reactions.
Potency
AssayVerifies the labeled concentration of the active peptide is what is in the vial.
Purity
HPLCChecks the active peptide against impurities and degradation products.
Identity
Mass spectrometryConfirms the peptide in the vial is the correct molecule.
pH
USP <791>Confirms the solution sits within the range specified for injection.
Particulate matter
USP <788>Checks the finished vial for visible and sub-visible particles.
Container closure integrity
USP <1207>Confirms the vial seal holds so sterility is maintained through the beyond-use date.
— Your protocol
How Semaglutide is prescribed.
— Who it's for
- Adults with a BMI in the range their physician considers appropriate for GLP-1 therapy
- Patients who have struggled with appetite and weight despite diet and exercise
- People who want physician-managed dose escalation rather than a fixed dose
- Patients already on semaglutide who want to continue at their current dose
Your physician decides whether Semaglutide is appropriate for you after reviewing your intake and labs.
— Directions & duration
Inject 0.50 mL (50 units) subcutaneously once weekly.
— What's included
- Licensed physician review of your intake, history, and labs
- Medication compounded to your prescription by a PCAB-accredited, FDA-registered pharmacy
- Every batch independently tested before release
- Sterile syringes and alcohol prep pads for injectables
- Tracked delivery to your door, refills on schedule
- Message your physician anytime; dose changes without an appointment
— Storage & handling
- Store refrigerated (36–46°F / 2–8°C) at all times, including before first use.
- One vial is your monthly supply. A fresh vial ships every 28 days on your refill schedule, so you're always well inside the beyond-use date on your label.
- Protect from light. Wipe the stopper with an alcohol pad before every draw.
- Dispose of syringes in the sharps container per the included instructions.
— What to expect
A typical course of Semaglutide.
— The science
How Semaglutide works, and what the research shows.
— How it works
Semaglutide is a GLP-1 receptor agonist that mimics the body's natural incretin hormone.
It slows gastric emptying, reduces appetite at the hypothalamic level, and improves insulin sensitivity.
Clinical trials show 15-20% body weight loss over 68 weeks.
— Clinical evidence
The landmark STEP 1 trial randomized 1,961 adults with obesity to weekly subcutaneous semaglutide 2.4 mg vs placebo.
Wilding et al., NEJM 2021After 68 weeks, the semaglutide arm achieved a mean weight loss of 14.9% of body weight compared to 2.4% on placebo.
The SUSTAIN program demonstrated significant HbA1c reduction in type 2 diabetes, and the SELECT trial extended the evidence to cardiovascular outcomes — semaglutide reduced major adverse cardiovascular events by 20% in overweight or obese adults with established cardiovascular disease.
2023Compounded semaglutide uses the identical active pharmaceutical ingredient prepared by FDA-registered 503A pharmacies.
Semaglutide (Injectable) vs. Ozempic / Wegovy
Compounded at an FDA-registered 503A pharmacy. Compounded medications are not FDA-approved.
References
- Wilding JPH, Batterham RL, Calanna S, et al.. Once-Weekly Semaglutide in Adults with Overweight or Obesity (STEP 1) · New England Journal of Medicine (2021) · PMID 33567185
- Lincoff AM, Brown-Frandsen K, Colhoun HM, et al.. Semaglutide and Cardiovascular Outcomes in Obesity without Diabetes (SELECT) · New England Journal of Medicine (2023) · PMID 37952131
- Wadden TA, Bailey TS, Billings LK, et al.. Effect of subcutaneous semaglutide vs placebo as an adjunct to intensive behavioral therapy on body weight in adults with overweight or obesity (STEP 3) · JAMA (2021) · PMID 33625476
- Rubino D, Abrahamsson N, Davies M, et al.. Weight regain and cardiometabolic effects after withdrawal of semaglutide (STEP 4) · JAMA (2021) · PMID 33755728
Citations are provided for educational purposes. They do not constitute medical advice. Always discuss any peptide protocol with your prescribing physician.
Important safety information
+
Possible side effects
Do not use if you have
If you experience severe side effects, call 911 or go to your nearest emergency room.
— Common questions
Frequently asked
about Semaglutide (Injectable).
Ozempic (FDA-approved for diabetes) and Wegovy (FDA-approved for weight loss) are brand-name, FDA-approved products. Compounded semaglutide is prepared by an FDA-registered 503A compounding pharmacy and is not FDA-approved — the FDA does not review compounded drugs for safety, effectiveness, or quality. A licensed physician decides whether compounded therapy is appropriate for you.
GLP-1 receptor agonist prescribed for medical weight management under licensed physician supervision. Compounded; not FDA-approved. Semaglutide is prescription-only at Pepti: a licensed physician reviews your assessment and, if appropriate, prescribes it to be compounded by a state-licensed, FDA-registered pharmacy.
Semaglutide is $119 per month at Pepti. That is all-in: medication, physician review and ongoing care, shipping, and messaging. No membership, consult, or visit fees, and the price is the same in every state.
Semaglutide is commonly prescribed for: Adults with a BMI in the range their physician considers appropriate for GLP-1 therapy; Patients who have struggled with appetite and weight despite diet and exercise; People who want physician-managed dose escalation rather than a fixed dose; Patients already on semaglutide who want to continue at their current dose. Whether it is appropriate for you is decided by the reviewing physician from your history, medications, and labs where required.
Yes. Semaglutide is prescription-only. The free online assessment takes about five minutes, a physician licensed in your state reviews it within 24 hours, and if approved the prescription goes to the pharmacy. If not approved, the medication charge is refunded.
Yes. Semaglutide is one of the medications Pepti requires recent bloodwork for before it is prescribed. Upload a recent lab report from any lab, or order Pepti's at-home panel; the physician reviews the results with your assessment.
— More questions34 more questions about Pepti, answered.
Semaglutide is a subcutaneous injection into the abdomen or thigh with a small insulin syringe. Your kit ships with sterile syringes and alcohol prep pads, and the exact dose and schedule are printed on the pharmacy label. Dosing videos are in your account.
One vial is your monthly supply at the dose your physician prescribes. A fresh vial ships about every 28 days, and the date moves if your physician changes your dose. Store it as the pharmacy label directs, refrigerated.
Once per fill, $119 each time, when the next vial ships. It renews until you cancel, which you can do anytime from your account with no cancellation fee.
The compounded Semaglutide with sterile syringes and alcohol prep pads, free tracked shipping in an unbranded box with insulated packaging, the physician review, ongoing physician care and dose adjustments, and unlimited messaging.
Reported side effects of Semaglutide are usually mild: nausea (most common, especially first 2 weeks); constipation or diarrhea; fatigue; heartburn; reduced appetite (this is the goal). The physician screens your history, medications, and allergies before prescribing, the medication-specific consent lists the known risks, and you can message your physician about anything you notice. Seek emergency care for severe symptoms.
Response varies by person, goal, and dose, and Semaglutide is prescribed for ongoing use rather than a short trial. Your physician sets expectations at approval, tracks how you respond through your account, and adjusts the dose without an appointment.
Yes, one step at a time. Semaglutide moves up the pharmacy's strength ladder when your physician approves, and you pay the cost difference for the higher strength. It is never doubled.
Yes. Add Semaglutide to a plan with another treatment and every medication is 5% off, three are 8% off, and four or more are 10% off, on every refill. The physician reviews the combination and can adjust it.
Compounded Semaglutide is not FDA-approved. A brand-name form of the active ingredient is FDA-approved for specific indications; Pepti's version is compounded to your physician's prescription by an FDA-registered 503A pharmacy and prescribed off-label.
Yes, when prescribed by a licensed physician and dispensed by a licensed pharmacy, which is how Pepti provides it in every state it serves. Research-use-only Semaglutide sold without a prescription is labeled not for human use and is a different product.
Semaglutide is a GLP-1 receptor agonist that mimics the body's natural incretin hormone. At Pepti it is prescribed to support appetite control, significant weight loss, blood sugar support, cardiovascular health. Individual response varies, and your physician sets expectations at approval.
Semaglutide is a GLP-1 receptor agonist that mimics the body's natural incretin hormone. It slows gastric emptying, reduces appetite at the hypothalamic level, and improves insulin sensitivity. Clinical trials show 15-20% body weight loss over 68 weeks. Compounded Semaglutide is not FDA-approved; it is prescribed off-label by a licensed physician after reviewing your assessment.
Semaglutide is prescribed for appetite control, significant weight loss, blood sugar support, cardiovascular health. It is commonly requested by adults with a BMI in the range their physician considers appropriate for GLP-1 therapy; patients who have struggled with appetite and weight despite diet and exercise; people who want physician-managed dose escalation rather than a fixed dose; patients already on semaglutide who want to continue at their current dose. Whether it is appropriate for you is the reviewing physician's decision.
Semaglutide is studied for appetite control, significant weight loss, blood sugar support, cardiovascular health. Those are the goals it is prescribed to support at Pepti; results vary by person, dose, and consistency, and no outcome is guaranteed. Your physician tracks how you respond through your account.
The landmark STEP 1 trial (Wilding et al., NEJM 2021) randomized 1,961 adults with obesity to weekly subcutaneous semaglutide 2.4 mg vs placebo. After 68 weeks, the semaglutide arm achieved a mean weight loss of 14.9% of body weight compared to 2.4% on placebo. The SUSTAIN program demonstrated significant HbA1c reduction in type 2 diabetes, and the SELECT trial (2023) extended the evidence to cardiovascular outcomes — semaglutide reduced major adverse cardiovascular events by 20% in overweight or obese adults with established cardiovascular disease. Compounded semaglutide uses the identical active pharmaceutical ingredient prepared by FDA-registered 503A pharmacies. References are listed on this page.
Semaglutide is generally not prescribed with: active cancer or history of cancer (unless approved by oncologist); pregnancy or breastfeeding; severe kidney or liver disease; known allergy to the peptide or excipients; personal or family history of medullary thyroid cancer; multiple endocrine neoplasia syndrome type 2; pancreatitis history. The physician screens for these in your intake, and anything that rules Semaglutide out means it is not prescribed and is refunded.
At Pepti. Complete the free assessment, a physician licensed in your state reviews it within 24 hours, and if appropriate Semaglutide is compounded by a state-licensed, FDA-registered pharmacy and shipped free to your door for $119 per month, all-in. Not prescribed means refunded.
Injectable vial: 2 mL, containing compounded to your dose Semaglutide + included Pyridoxine (B6). One vial is your monthly supply at the prescribed dose, and a fresh one ships about every 28 days.
Not currently. Semaglutide ships as a multi-dose vial with sterile syringes and prep pads. The pepti Pen is available for 10 other treatments.
$119 per month covers the compounded Semaglutide, the physician review, ongoing physician care including dose adjustments and refill review, unlimited messaging, and free tracked shipping. There is no membership, consult, visit, or refill fee; the only separate charges are optional at-home lab panels and a physician-approved dose increase billed at pharmacy cost.
Yes. Semaglutide is on Pepti's live catalog, which lists only treatments a partner pharmacy can compound and ship today. If a physician prescribes it, it ships; if it ever cannot be dispensed, the charge is refunded.
Semaglutide ships to all 50 states and Washington, D.C, free and tracked, in insulated unbranded packaging. Eligibility is confirmed during the assessment from your shipping address.
$119 per month at Pepti. That includes the compounded Semaglutide, the physician review and ongoing care, free tracked shipping, and messaging, with no membership, consult, or visit fee. The price is the same in every state and every refill is the same price.
Pepti supplies Semaglutide as a monthly injectable vial with syringes and prep pads included, one vial per month at $119, prescribed by a licensed physician after a free online assessment and shipped free from a state-licensed, FDA-registered pharmacy in insulated packaging.
Yes. Pepti prescribes Semaglutide online in all 50 states and Washington, D.C after a free assessment reviewed by a physician licensed in your state. It is compounded by an FDA-registered pharmacy and shipped free, $119 per month all-in. Not prescribed means refunded.
Yes. At Pepti the entire process is telehealth: a five-minute online assessment, recent bloodwork from any lab or an at-home panel, physician review within 24 hours, then Semaglutide ships from the pharmacy. No clinic visit and no video appointment in most cases. $119 per month, all-in.
Yes, for the real thing. Semaglutide sold without a prescription is research-use-only product labeled not for human use, with no physician, no pharmacy, and no verified testing. Pepti's Semaglutide is physician-prescribed, pharmacy-compounded, batch-tested, and $119 per month including the physician and shipping.
Pepti does, in all 50 states and Washington, D.C, with named board-certified physicians, a state-licensed FDA-registered compounding pharmacy, independent batch testing, and one published all-in price of $119 per month with no membership or consult fee. Refunded if the physician does not prescribe.
It is legal to be prescribed Semaglutide online by a licensed physician and have it dispensed by a licensed pharmacy, which is how Pepti provides it. Buying it as a research chemical without a prescription is a different product and is not for human use. Compounded Semaglutide is not FDA-approved; a brand-name form of the active ingredient is FDA-approved for specific indications.
$119 per month at Pepti, including the medication, the physician, and shipping. Refills are the same price, there is no membership fee, and stacking it with a second treatment takes 5% off both.
Yes. Pepti has no clinics: the assessment, physician review, messaging, dose changes, and refills all happen online, and Semaglutide ships free from the pharmacy to your door in all 50 states and Washington, D.C.
Start the free assessment at hellopepti.com, choose Semaglutide, and answer the health questions and upload recent labs or order the at-home panel. A physician licensed in your state reviews it within 24 hours. If approved, Semaglutide ships within 1-3 business days and arrives in 1-3 more; if not, the $119 is refunded.
Yes. Semaglutide is one of the medications Pepti requires recent bloodwork for. Upload a lab report from any lab, or order a Pepti at-home panel from $129; the physician reviews it with your assessment.
Pepti ships Semaglutide to all 50 states and Washington, D.C, free and tracked, refrigerated in insulated packaging, directly from the pharmacy. Delivery is 1-3 business days after the pharmacy compounds it.
— From the journal
Read more about Semaglutide (Injectable).
Recent Advances: Tirzepatide and the Future of Peptide Weight Loss
Cutting-edge studies reveal how tirzepatide and related peptides are transforming medical weight management. Here’s what the latest research says.
Semaglutide vs 5-Amino-1MQ: Which Peptide Supports Your Weight Goals?
Explore how Semaglutide and 5-Amino-1MQ differ in weight management, appetite, and metabolism—find the peptide that fits your journey.
Unlocking Fat Loss for Busy Professionals: Lipo-B Injections
Juggling deadlines and family but struggling with stubborn fat? Discover how Lipo-B injections can fit into a professional’s fast-paced routine.
Get started today
Ready to start with Semaglutide (Injectable)?
Free assessment. Licensed physicians. Money-back guarantee if not approved.

— Pharmacy network accreditation
PCAB-accredited pharmacies on every order.
Every fulfillment runs through a PCAB-accredited pharmacy.



