Dihexa (Injectable)
Neuroprotection & brain health
All-in monthly price
No membership fee · this is the full price · free shipping · avg 4-week supply
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This treatment requires licensed provider review and approval. Treatment is not guaranteed. If prescribed, medication is fulfilled by a licensed U.S. pharmacy where permitted by law. Compounded medications are not FDA-approved or FDA-cleared.
Reviewed by Dr. Gene, MD · Board-certified Family Medicine
Every Pepti prescription is reviewed by a licensed U.S. physician before it's dispensed — and only provided if clinically appropriate.
Dihexa (Injectable)
Dihexa is a small peptide studied for helping brain cells form new connections, with research focused on memory and thinking. Human evidence is limited, so it is prescribed only where a physician judges it appropriate. Compounded; not FDA-approved.
About a 4-week supply supply at the standard prescribed dose — your physician confirms exact dosing.
A licensed US physician reviews your intake and prescribes when appropriate.
Compounded fresh at a US pharmacy and shipped cold-chain to your door.
Every order ships free — medication, physician care and refills, one all-in price.
Amounts shown are per unit. Compounded fresh at a US FDA-registered pharmacy.
Every batch independently tested
Every medication batch dispensed through Pepti is independently tested by a qualified third-party laboratory for applicable quality and safety standards before the pharmacy releases it. Batches are tested to the same standard used by 503B outsourcing facilities.
Confirms the finished preparation is free of viable microorganisms.
Screens for endotoxins that can cause fever or inflammatory reactions.
Verifies the labeled concentration of the active peptide is what is in the vial.
- Lot 102626-DIH-1
Tested 2026-10-28 · Biolink Life Sciences Carolinas
Sterility
Sterile
Endotoxin
<2 EU/mL
Potency
99.4%
- Lot 101926-DIH-1
Tested 2026-10-21 · Biolink Life Sciences Carolinas
Sterility
Sterile
Endotoxin
<2 EU/mL
Potency
99.9%
- Lot 101226-DIH-1
Tested 2026-10-14 · Biolink Life Sciences Carolinas
Sterility
Sterile
Endotoxin
<2 EU/mL
Potency
98.9%
How Dihexa is prescribed.
- Adults who feel their memory or recall is not what it was
- People who want a brain-focused peptide as part of a longevity protocol
- Patients who understand the evidence is from animal studies and are comfortable with that
- Anyone who found nootropic supplements did nothing
Your physician decides whether Dihexa is appropriate for you after reviewing your intake and labs.
Inject 0.25 mL (25 units) subcutaneously once daily Monday through Friday.
- Licensed physician review of your intake, history, and labs
- Medication compounded to your prescription by a PCAB-accredited, FDA-registered pharmacy
- Every batch independently tested before release
- Sterile syringes and alcohol prep pads for injectables
- Tracked delivery to your door, refills on schedule
- Message your physician anytime; dose changes without an appointment
- Store refrigerated (36–46°F / 2–8°C) at all times, including before first use.
- One vial is your monthly supply. A fresh vial ships every 28 days on your refill schedule, so you're always well inside the beyond-use date on your label.
- Protect from light. Wipe the stopper with an alcohol pad before every draw.
- Dispose of syringes in the sharps container per the included instructions.
A typical course of Dihexa.
Everything published
about Dihexa.
How it is described to work, pathway by pathway. What the research shows and what it does not. Where it stands with the FDA, dated and sourced.
Read the referencepeer-reviewed, each verified on PubMed
mechanism, evidence, dosing, safety, FAQ
2026 · checked against fda.gov, not memory
How Dihexa works, and what the research shows.
Dihexa boosts a growth factor that helps neurons build new connections with each other.
Those connections are the physical basis of memory, which is why it is studied for cognitive decline.
Animal studies reported reversal of memory deficits in rodent models.
McCoy and colleagues 2013, Benoist and colleagues 2014There are no published controlled human trials.
References
- McCoy AT, Benoist CC, Wright JW et al.. Evaluation of metabolically stabilized angiotensin IV analogs as procognitive/antidementia agents · J Pharmacol Exp Ther (2013) · PMID 23055539
- Benoist CC, Kawas LH, Zhu M et al.. The procognitive and synaptogenic effects of angiotensin IV-derived peptides are dependent on activation of the hepatocyte growth factor/c-met system · J Pharmacol Exp Ther (2014) · PMID 25187433
- Sun X, Deng Y, Fu X et al.. AngIV-Analog Dihexa Rescues Cognitive Impairment and Recovers Memory in the APP/PS1 Mouse via the PI3K/AKT Signaling Pathway · Brain Sci (2021) · PMID 34827486
- Ho JK, Nation DA. Cognitive benefits of angiotensin IV and angiotensin-(1-7): A systematic review of experimental studies · Neurosci Biobehav Rev (2018) · PMID 29733881
- Wright JW, Harding JW. The Brain Hepatocyte Growth Factor/c-Met Receptor System: A New Target for the Treatment of Alzheimer's Disease · J Alzheimers Dis (2015) · PMID 25649658
- Wright JW, Kawas LH, Harding JW. The development of small molecule angiotensin IV analogs to treat Alzheimer's and Parkinson's diseases · Prog Neurobiol (2015) · PMID 25455861
- Wells RG, Azzam AF, Hiller AL et al.. Effects of an Angiotensin IV Analog on 3-Nitropropionic Acid-Induced Huntington's Disease-Like Symptoms in Rats · J Huntingtons Dis (2024) · PMID 38489193
Citations are provided for educational purposes. They do not constitute medical advice. Always discuss any peptide protocol with your prescribing physician.
Important safety information
+
Possible side effects
Do not use if you have
If you experience severe side effects, call 911 or go to your nearest emergency room.
5 mL multi-dose vial, Dihexa 1 mg/mL (5 mg Dihexa per vial)
Frequently asked
about Dihexa (Injectable).
Dihexa is a small peptide studied for helping brain cells form new connections, with research focused on memory and thinking. Human evidence is limited, so it is prescribed only where a physician judges it appropriate. Compounded; not FDA-approved. Dihexa is prescription-only at Pepti: a licensed physician reviews your assessment and, if appropriate, prescribes it to be compounded by a state-licensed, FDA-registered pharmacy.
Dihexa is $219 per month at Pepti. That is all-in: medication, physician review and ongoing care, shipping, and messaging. No membership, consult, or visit fees, and the price is the same in every state.
Dihexa is commonly prescribed for: Adults who feel their memory or recall is not what it was; People who want a brain-focused peptide as part of a longevity protocol; Patients who understand the evidence is from animal studies and are comfortable with that; Anyone who found nootropic supplements did nothing. Whether it is appropriate for you is decided by the reviewing physician from your history, medications, and labs where required.
Yes. Dihexa is prescription-only. The free online assessment takes about five minutes, a physician licensed in your state reviews it within 4 hours, and if approved the prescription goes to the pharmacy. If not approved, the medication charge is refunded.
No. Dihexa can be prescribed from the assessment alone. If your physician wants labs for your care, they'll ask through your account; upload a recent lab report from any lab at no charge, or order Pepti's at-home panel.
Dihexa is a subcutaneous injection into the abdomen or thigh with a small insulin syringe. Your kit ships with sterile syringes and alcohol prep pads, and the exact dose and schedule are printed on the pharmacy label. Dosing videos are in your account.
33 more questions about Pepti, answered.Show fewer
One vial is your monthly supply at the dose your physician prescribes. A fresh vial ships about every 28 days, and the date moves if your physician changes your dose. Store it as the pharmacy label directs, refrigerated.
Once per fill, $219 each time, when the next vial ships. It renews until you cancel, which you can do anytime from your account with no cancellation fee.
The compounded Dihexa with sterile syringes and alcohol prep pads, free tracked shipping in an unbranded box with insulated packaging, the physician review, ongoing physician care and dose adjustments, and unlimited messaging.
Reported side effects of Dihexa are usually mild: mild redness or swelling at injection site; temporary fatigue or headache; mild nausea (uncommon). The physician screens your history, medications, and allergies before prescribing, the medication-specific consent lists the known risks, and you can message your physician about anything you notice. Seek emergency care for severe symptoms.
Response varies by person, goal, and dose, and Dihexa is prescribed for ongoing use rather than a short trial. Your physician sets expectations at approval, tracks how you respond through your account, and adjusts the dose without an appointment.
Yes. Request it from your account or the app; your physician approves or declines. If approved you pay for the additional medication at the pharmacy's cost and the new dose applies to your next shipment.
Yes. Add Dihexa to a plan with another treatment and both go through one assessment and one physician review, shipping together on one schedule. Each keeps its own catalog price. The physician reviews the combination and can adjust it.
No. Compounded Dihexa is not FDA-approved. It is prepared to your physician's prescription by a state-licensed, FDA-registered 503A pharmacy and every batch is independently tested before release.
Yes, when prescribed by a licensed physician and dispensed by a licensed pharmacy, which is how Pepti provides it in every state it serves. Research-use-only Dihexa sold without a prescription is labeled not for human use and is a different product.
Dihexa boosts a growth factor that helps neurons build new connections with each other. At Pepti it is prescribed to support studied for new brain-cell connections, memory and thinking research, evidence is from animal studies, daily injection, monday to friday. Individual response varies, and your physician sets expectations at approval.
Dihexa boosts a growth factor that helps neurons build new connections with each other. Those connections are the physical basis of memory, which is why it is studied for cognitive decline. Compounded Dihexa is not FDA-approved; it is prescribed off-label by a licensed physician after reviewing your assessment.
Dihexa is prescribed for studied for new brain-cell connections, memory and thinking research, evidence is from animal studies, daily injection, monday to friday. It is commonly requested by adults who feel their memory or recall is not what it was; people who want a brain-focused peptide as part of a longevity protocol; patients who understand the evidence is from animal studies and are comfortable with that; Anyone who found nootropic supplements did nothing. Whether it is appropriate for you is the reviewing physician's decision.
Dihexa is studied for studied for new brain-cell connections, memory and thinking research, evidence is from animal studies, daily injection, monday to friday. Those are the goals it is prescribed to support at Pepti; results vary by person, dose, and consistency, and no outcome is guaranteed. Your physician tracks how you respond through your account.
Animal studies (McCoy and colleagues 2013, Benoist and colleagues 2014) reported reversal of memory deficits in rodent models. There are no published controlled human trials. References are listed on this page.
Dihexa is generally not prescribed with: active cancer or history of cancer (unless approved by oncologist); pregnancy or breastfeeding; severe kidney or liver disease; known allergy to the peptide or excipients. The physician screens for these in your intake, and anything that rules Dihexa out means it is not prescribed and is refunded.
At Pepti. Complete the free assessment, a physician licensed in your state reviews it within 4 hours, and if appropriate Dihexa is compounded by a state-licensed, FDA-registered pharmacy and shipped free to your door for $219 per month, all-in. Not prescribed means refunded.
Injectable vial: 5 mL at 1 mg/mL, containing 5 mg Dihexa. One vial is your monthly supply at the prescribed dose, and a fresh one ships about every 28 days.
Not currently. Dihexa ships as a multi-dose vial with sterile syringes and prep pads. The pepti Pen is available for 10 other treatments.
$219 per month covers the compounded Dihexa, the physician review, ongoing physician care including dose adjustments and refill review, unlimited messaging, and free tracked shipping. There is no membership, consult, visit, or refill fee; the only separate charges are optional at-home lab panels and a physician-approved dose increase billed at pharmacy cost.
Yes. Dihexa is on Pepti's live catalog, which lists only treatments a partner pharmacy can compound and ship today. If a physician prescribes it, it ships; if it ever cannot be dispensed, the charge is refunded.
Dihexa ships to 50 states, free and tracked, in insulated unbranded packaging. Eligibility is confirmed during the assessment from your shipping address.
$219 per month at Pepti. That includes the compounded Dihexa, the physician review and ongoing care, free tracked shipping, and messaging, with no membership, consult, or visit fee. The price is the same in every state and every refill is the same price.
Pepti supplies Dihexa as a monthly injectable vial with syringes and prep pads included, one vial per month at $219, prescribed by a licensed physician after a free online assessment and shipped free from a state-licensed, FDA-registered pharmacy in insulated packaging.
Yes. Pepti prescribes Dihexa online in 50 states after a free assessment reviewed by a physician licensed in your state. It is compounded by an FDA-registered pharmacy and shipped free, $219 per month all-in. Not prescribed means refunded.
Yes. At Pepti the entire process is telehealth: a five-minute online assessment, physician review within 4 hours, then Dihexa ships from the pharmacy. No clinic visit and no video appointment in most cases. $219 per month, all-in.
Yes, for the real thing. Dihexa sold without a prescription is research-use-only product labeled not for human use, with no physician, no pharmacy, and no verified testing. Pepti's Dihexa is physician-prescribed, pharmacy-compounded, batch-tested, and $219 per month including the physician and shipping.
Pepti does, in 50 states, with named board-certified physicians, a state-licensed FDA-registered compounding pharmacy, independent batch testing, and one published all-in price of $219 per month with no membership or consult fee. Refunded if the physician does not prescribe.
It is legal to be prescribed Dihexa online by a licensed physician and have it dispensed by a licensed pharmacy, which is how Pepti provides it. Buying it as a research chemical without a prescription is a different product and is not for human use. Compounded Dihexa is not FDA-approved.
$219 per month at Pepti, including the medication, the physician, and shipping. Refills are the same price and there is no membership fee.
Yes. Pepti has no clinics: the assessment, physician review, messaging, dose changes, and refills all happen online, and Dihexa ships free from the pharmacy to your door in 50 states.
Start the free assessment at hellopepti.com, choose Dihexa, and answer the health questions. A physician licensed in your state reviews it within 4 hours. If approved, Dihexa ships within 1-3 business days and arrives in 1-3 more; if not, the $219 is refunded.
No. Dihexa can be prescribed from the assessment alone at Pepti. If your physician wants labs for your care, they'll ask through your account; upload a lab report from any lab, or order a Pepti at-home panel from $129.
Pepti ships Dihexa to 50 states, free and tracked, refrigerated in insulated packaging, directly from the pharmacy. Delivery is 1-3 business days after the pharmacy compounds it.
Questions people ask
about Dihexa (Injectable).
- Dihexa: What It Is, Where to Get It Prescribed, and What It CostsDihexa — 5 mL multi-dose vial, Dihexa 1 mg/mL (5 mg Dihexa per vial). Specification, mechanism, dosing, formats, state availability and how to get it prescribed.
- Dihexa vs Semax: Mechanism, Evidence, Cost, and Which One FitsDihexa and Semax are both prescribed for memory and focus, but they come from different systems and have very different evidence. A side-by-side of what each is, how each is described to work, the human data, FDA status, dosing, price and who suits which.
- Dihexa Dosage: How Pepti Prescribes It, in Units, mL and mgThe Dihexa dosage Pepti prescribes: 0.25 mL (25 units on a U-100 insulin syringe) under the skin once daily Monday through Friday, 0.25 mg per dose from the 1 mg/mL vial, 20 doses per vial. Includes a units, mL and mg chart, how long a vial lasts, why no human dose exists, what changes the directions, and side effects.
- Dihexa Side Effects: What Is Reported, the Cancer Question, and What to ReportA practical reference to Dihexa side effects: what prescribers report (injection-site reactions, headache, a wired feeling, poor sleep if dosed late), why there is no human safety data, the theoretical growth-pathway concern, when to message your care team, what needs emergency care, and who should not take it.
- Dihexa Benefits: What the Research Actually ShowsThe benefits claimed for the Dihexa peptide, one at a time: memory and learning, Alzheimer's-type pathology, new synaptic connections, the "more potent than BDNF" line, focus and brain fog, and other neurological conditions. Each is labelled as rodent, cell or human research, with an honest strength-of-evidence rating and the retraction history most pages leave out.
- Can You Take Dihexa With Tirzepatide or Semaglutide?Whether Dihexa can be prescribed alongside tirzepatide or semaglutide, how the two differ, why there is no data on the pairing (Dihexa has no human data at all), the cancer-history question both raise for different reasons, how the schedules fit, and how to add it properly.
- How Long Does Dihexa Take to Work? Why No Study Can Answer It YetDihexa has never been given to people in a published study, so there is no human timeline at all. What the rat and mouse studies measured, why their results cannot be turned into weeks, what the 2025 retractions changed, and how to judge Dihexa on a 28-day vial.
- Do You Need a Prescription for Dihexa? Is It Legal to Buy Online?Yes, injectable Dihexa needs a prescription. Why, where dihexa acetate stands with the FDA in 2026 (out of Category 2, advisory committee review due by February 2027), what "research use only" Dihexa is, what is legal to buy online, and how Pepti prescribes it.
- Best Place to Get Dihexa Online: How to Choose a ProviderWhere to get injectable Dihexa prescribed online: the provider checklist, why honesty about Dihexa's evidence is itself a test, the red flags, when a physician may suggest something else, and Pepti's offering with vial, directions and price.
- Dihexa for Women: What the Research Has Looked At, and What to Check FirstWhat research has actually studied about Dihexa in women (nothing: there is no human data in either sex), the causes of brain fog that are more common in women and worth ruling out first, perimenopause, pregnancy and breastfeeding, breast and ovarian cancer history, and how to get Dihexa prescribed.
- Dihexa for Men: What the Research Has Looked At, and What to Check FirstWhat research has actually studied about Dihexa in men (nothing: there is no human data in either sex), the causes of poor memory and focus in men that are worth ruling out first, testosterone, cancer history, fertility, sport, and how to get Dihexa prescribed.
- Is Dihexa Banned in Sports? WADA, the S0 Class and What Tested Athletes Should KnowDihexa is not named on the 2026 WADA Prohibited List, but it has no approval for human use anywhere and no human exposure data, which is exactly the position the S0 non-approved substances class is written around. What that means for tested athletes, how other cognitive peptides and blends are classified, workplace drug tests, and Dihexa's FDA status.
- Peptides for Brain Fog and Focus: What Is Prescribed, and What WorksThe peptides used for brain fog and focus, what each one does in the brain, how they are taken, what they cost, and the medical causes worth ruling out first.
- How Much Do Peptides Cost? Real Monthly Prices and What Drives ThemWhat prescription peptides actually cost per month, why single molecules price differently from four-peptide blends, which costs providers hide behind a low headline, and how to compare.
- How to get Dihexa prescribed online
- How Much Does Dihexa Cost?Dihexa cost in 2026: $219 per month all-in at Pepti — compounded medication, physician review, and shipping included. No membership or consult fees.
Read more about Dihexa (Injectable).
Do You Need a Prescription for Dihexa? Is It Legal to Buy Online?
Yes, injectable Dihexa needs a prescription. Why, where dihexa acetate stands with the FDA in 2026 (out of Category 2, advisory committee review due by February 2027), what "research use only" Dihexa is, what is legal to buy online, and how Pepti prescribes it.
Best Place to Get Dihexa Online: How to Choose a Provider
Where to get injectable Dihexa prescribed online: the provider checklist, why honesty about Dihexa's evidence is itself a test, the red flags, when a physician may suggest something else, and Pepti's offering with vial, directions and price.
Dihexa: What It Is, Where to Get It Prescribed, and What It Costs
Dihexa — 5 mL multi-dose vial, Dihexa 1 mg/mL (5 mg Dihexa per vial). Specification, mechanism, dosing, formats, state availability and how to get it prescribed.
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