
GHK-Cu (Injectable)
Systemic skin & collagen repair
Choose your strength
Every strength is a 4-week supply. A higher strength means more medication per dose on the same monthly cycle. Your provider confirms the dose at review.
All-in monthly price · 50mg
No membership fee · this is the full price · free shipping · avg 4-week supply
Add in-depth bloodwork
Optional — add a physician-reviewed at-home blood panel to your plan.
Your sex-hormone baseline plus the safety markers that matter on therapy — blood counts, liver and kidney function — from one painless upper-arm device. Matched to your sex (PSA for men; progesterone & FSH for women). No needle, no clinic, physician-reviewed.
This treatment requires licensed provider review and approval. Treatment is not guaranteed. If prescribed, medication is fulfilled by a licensed U.S. pharmacy where permitted by law. Compounded medications are not FDA-approved or FDA-cleared.

Reviewed by Dr. Gene, MD · Board-certified Family Medicine
Every Pepti prescription is reviewed by a licensed U.S. physician before it's dispensed — and only provided if clinically appropriate.
GHK-Cu (Injectable)
Physician-prescribed copper peptide therapy, compounded at FDA-registered US pharmacies. Free online assessment. Treatment not guaranteed. Free shipping where available.
About a 4-week supply supply at the standard prescribed dose — your physician confirms exact dosing.
A licensed US physician reviews your intake and prescribes when appropriate.
Compounded fresh at a US pharmacy and shipped cold-chain to your door.
Every order ships free — medication, physician care and refills, one all-in price.
Amounts shown are per unit. Compounded fresh at a US FDA-registered pharmacy.
Every batch independently tested
Every medication batch dispensed through Pepti is independently tested by a qualified third-party laboratory for applicable quality and safety standards before the pharmacy releases it. Batches are tested to the same standard used by 503B outsourcing facilities.
Confirms the finished preparation is free of viable microorganisms.
Screens for endotoxins that can cause fever or inflammatory reactions.
Verifies the labeled concentration of the active peptide is what is in the vial.
Checks the active peptide against impurities and degradation products.
Confirms the peptide in the vial is the correct molecule.
Confirms the solution sits within the range specified for injection.
Checks the finished vial for visible and sub-visible particles.
Confirms the vial seal holds so sterility is maintained through the beyond-use date.
- Lot 100526-GHK-10
Tested 2026-10-07 · Biolink Life Sciences Carolinas
Sterility
Sterile
Endotoxin
<2 EU/mL
Potency
100.1%
- Lot 092826-GHK-10
Tested 2026-09-30 · Biolink Life Sciences Carolinas
Sterility
Sterile
Endotoxin
<2 EU/mL
Potency
100.0%
- Lot 092126-GHK-10
Tested 2026-09-23 · Biolink Life Sciences Carolinas
Sterility
Sterile
Endotoxin
<2 EU/mL
Potency
100.2%
How GHK-Cu is prescribed.
- Adults focused on skin quality, collagen, and hair
- Patients recovering from procedures or wounds their physician is managing
- People who want a systemic skin-support peptide rather than a topical
Your physician decides whether GHK-Cu is appropriate for you after reviewing your intake and labs.
Inject 0.25 mL (25 units) subcutaneously once daily Monday through Friday.
- Licensed physician review of your intake, history, and labs
- Medication compounded to your prescription by a PCAB-accredited, FDA-registered pharmacy
- Every batch independently tested before release
- Sterile syringes and alcohol prep pads for injectables
- Tracked delivery to your door, refills on schedule
- Message your physician anytime; dose changes without an appointment
- Store refrigerated (36–46°F / 2–8°C) at all times, including before first use.
- One vial is your monthly supply. A fresh vial ships every 28 days on your refill schedule, so you're always well inside the beyond-use date on your label.
- Protect from light. Wipe the stopper with an alcohol pad before every draw.
- Dispose of syringes in the sharps container per the included instructions.
A typical course of GHK-Cu.
Everything published
about GHK-Cu.
How it is described to work, pathway by pathway. What the research shows and what it does not. Where it stands with the FDA, dated and sourced.
Read the referencepeer-reviewed, each verified on PubMed
mechanism, evidence, dosing, safety, FAQ
2026 · checked against fda.gov, not memory
How GHK-Cu works, and what the research shows.
GHK-Cu is a copper peptide that stimulates collagen I and III, elastin, decorin, and glycosaminoglycans.
It promotes hair follicle growth, accelerates wound healing, and drives skin remodeling at the dermal level.
GHK-Cu is one of the most-studied peptides in dermatology, with over 100 published papers since Pickart's foundational work in the 1970s.
Documented effects include collagen synthesis upregulation, accelerated wound healing in diabetic mice, and gene expression changes consistent with skin regeneration.
Maquart et al., FEBS Lett 1988Pickart, Brief Funct Genomics 2017Pickart & Margolina's 2018 Cosmetics review reported clinical trials showing improvements in skin firmness, elasticity, fine lines, and wound healing.
Mechanistically GHK-Cu also modulates antioxidant defenses (SOD, glutathione) and reduces inflammatory cytokines.
The peptide is a small ligand that releases copper into cells in a controlled manner, supporting both the structural collagen scaffold and the antioxidant defense system simultaneously.
References
- Maquart FX, Pickart L, Laurent M, et al.. Stimulation of collagen synthesis in cultured fibroblasts by GHK-Cu · FEBS Letters (1988) · PMID 3169264
- Pickart L, Margolina A. GHK peptide as a natural modulator of multiple cellular pathways in skin regeneration · BioMed Research International (2015) · PMID 26236730
- Pickart L, Margolina A. Regenerative and protective actions of the GHK-Cu peptide in the light of the new gene data · International Journal of Molecular Sciences (2018) · PMID 29986520
- Pickart L. The human tri-peptide GHK and tissue remodeling · Journal of Biomaterials Science, Polymer Edition (2008) · PMID 18644225
- Pickart L, Thaler MM. Tripeptide in human serum which prolongs survival of normal liver cells and stimulates growth in neoplastic liver · Nature: New Biology (1973) · PMID 4349963
- Lane TF, et al.. SPARC is a source of copper-binding peptides that stimulate angiogenesis · Journal of Cell Biology (1994) · PMID 7514608
- Maquart FX, et al.. In vivo stimulation of connective tissue accumulation by the tripeptide-copper complex glycyl-L-histidyl-L-lysine-Cu2+ in rat experimental wounds · Journal of Clinical Investigation (1993) · PMID 8227353
- Mulder GD, et al.. Enhanced healing of ulcers in patients with diabetes by topical treatment with glycyl-l-histidyl-l-lysine copper · Wound Repair and Regeneration (1994) · PMID 17147644
- Siméon A, et al.. Expression and activation of matrix metalloproteinases in wounds: modulation by the tripeptide-copper complex glycyl-L-histidyl-L-lysine-Cu2+ · Journal of Investigative Dermatology (1999) · PMID 10383745
- Siméon A, et al.. The tripeptide-copper complex glycyl-L-histidyl-L-lysine-Cu2+ stimulates matrix metalloproteinase-2 expression by fibroblast cultures · Life Sciences (2000) · PMID 11045606
- Miller TR, et al.. Effects of topical copper tripeptide complex on CO2 laser-resurfaced skin · Archives of Facial Plastic Surgery (2006) · PMID 16847171
- Pyo HK, et al.. The effect of tripeptide-copper complex on human hair growth in vitro · Archives of Pharmacal Research (2007) · PMID 17703734
- Campbell JD, et al.. A gene expression signature of emphysema-related lung destruction and its reversal by the tripeptide GHK · Genome Medicine (2012) · PMID 22937864
- Pickart L, et al.. The human tripeptide GHK-Cu in prevention of oxidative stress and degenerative conditions of aging: implications for cognitive health · Oxidative Medicine and Cellular Longevity (2012) · PMID 22666519
- Gruchlik A, et al.. Effect of Gly-Gly-His, Gly-His-Lys and their copper complexes on TNF-alpha-dependent IL-6 secretion in normal human dermal fibroblasts · Acta Poloniae Pharmaceutica (2012) · PMID 23285694
- Park JR, et al.. The tri-peptide GHK-Cu complex ameliorates lipopolysaccharide-induced acute lung injury in mice · Oncotarget (2016) · PMID 27517151
- Ma WH, et al.. Protective effects of GHK-Cu in bleomycin-induced pulmonary fibrosis via anti-oxidative stress and anti-inflammation pathways · Life Sciences (2020) · PMID 31809714
- Zhang Q, et al.. Glycyl-L-histidyl-L-lysine-Cu(2+) attenuates cigarette smoke-induced pulmonary emphysema and inflammation by reducing oxidative stress pathway · Frontiers in Molecular Biosciences (2022) · PMID 35936787
- Hiyama Y, Yamada T, Tomota E, Tomita T, et al.. Characterizing clinical patterns and associated factors of zinc-induced copper deficiency: Insights from large-scale pharmacovigilance databases · Clin Nutr ESPEN (2026) · PMID 42217623
- Gaetke LM, Chow CK. Copper toxicity, oxidative stress, and antioxidant nutrients · Toxicology (2003) · PMID 12821289
- Członkowska A, Litwin T, Dusek P, et al.. Wilson disease · Nature Reviews Disease Primers (2018) · PMID 30190489
- Hostynek JJ, Dreher F, Maibach HI. Human skin penetration of a copper tripeptide in vitro as a function of skin layer · Inflammation Research (2011) · PMID 20721598
- Hostynek JJ, Maibach HI. Copper hypersensitivity: dermatologic aspects · Dermatologic Therapy (2004) · PMID 15327478
- Pickart L, Vasquez-Soltero JM, Margolina A. GHK and DNA: resetting the human genome to health · BioMed Research International (2014) · PMID 25302294
- Pickart L, Vasquez-Soltero JM, Margolina A. The Effect of the Human Peptide GHK on Gene Expression Relevant to Nervous System Function and Cognitive Decline · Brain Sciences (2017) · PMID 28212278
- Trachy RE, Fors TD, Pickart L, Uno H. The hair follicle-stimulating properties of peptide copper complexes. Results in C3H mice · Annals of the New York Academy of Sciences (1991) · PMID 1809108
- Uno H, Kurata S. Chemical agents and peptides affect hair growth · Journal of Investigative Dermatology (1993) · PMID 8326148
- Lee WJ, Sim HB, Jang YH, Lee SJ, Kim DW, Yim SH. Efficacy of a Complex of 5-Aminolevulinic Acid and Glycyl-Histidyl-Lysine Peptide on Hair Growth · Annals of Dermatology (2016) · PMID 27489425
- Fu SC, Cheuk YC, Chiu WY et al.. Tripeptide-copper complex GHK-Cu (II) transiently improved healing outcome in a rat model of ACL reconstruction · J Orthop Res (2015) · PMID 25731775
- Fisher GJ, Kang S, Varani J et al.. Mechanisms of photoaging and chronological skin aging · Arch Dermatol (2002) · PMID 12437452
- Varani J, Dame MK, Rittie L et al.. Decreased collagen production in chronologically aged skin: roles of age-dependent alteration in fibroblast function and defective mechanical stimulation · Am J Pathol (2006) · PMID 16723701
- Quan T, Fisher GJ. Role of Age-Associated Alterations of the Dermal Extracellular Matrix Microenvironment in Human Skin Aging: A Mini-Review · Gerontology (2015) · PMID 25660807
- Kang YA, Choi HR, Na JI et al.. Copper-GHK increases integrin expression and p63 positivity by keratinocytes · Arch Dermatol Res (2009) · PMID 19319546
- Gorouhi F, Maibach HI. Role of topical peptides in preventing or treating aged skin · Int J Cosmet Sci (2009) · PMID 19570099
- Verzijl N, DeGroot J, Thorpe SR et al.. Effect of collagen turnover on the accumulation of advanced glycation end products · J Biol Chem (2000) · PMID 10976109
- Parker NP, Ardeshirpour F, Schmechel SC, Lassig AA. Effects of topical copper tripeptide complex on wound healing in an irradiated rat model · Otolaryngol Head Neck Surg (2013) · PMID 23744835
- Krug O, Thomas A, Walpurgis K, et al.. Identification of black market products and potential doping agents in Germany 2010-2013 · European Journal of Clinical Pharmacology (2014) · PMID 25168622
- Weber C, Krug O, Kamber M, et al.. Qualitative and Semiquantitative Analysis of Doping Products Seized at the Swiss Border · Substance Use & Misuse (2017) · PMID 28156209
Citations are provided for educational purposes. They do not constitute medical advice. Always discuss any peptide protocol with your prescribing physician.
Important safety information
+
Possible side effects
Do not use if you have
If you experience severe side effects, call 911 or go to your nearest emergency room.
5 mL multi-dose vial, GHK-Cu 10 mg/mL (50 mg GHK-Cu per vial)
Frequently asked
about GHK-Cu (Injectable).
Physician-prescribed copper peptide therapy, compounded at FDA-registered US pharmacies. Free online assessment. Treatment not guaranteed. Free shipping where available. GHK-Cu is prescription-only at Pepti: a licensed physician reviews your assessment and, if appropriate, prescribes it to be compounded by a state-licensed, FDA-registered pharmacy.
GHK-Cu is $239 per month at Pepti. That is all-in: medication, physician review and ongoing care, shipping, and messaging. No membership, consult, or visit fees, and the price is the same in every state.
GHK-Cu is commonly prescribed for: Adults focused on skin quality, collagen, and hair; Patients recovering from procedures or wounds their physician is managing; People who want a systemic skin-support peptide rather than a topical. Whether it is appropriate for you is decided by the reviewing physician from your history, medications, and labs where required.
Yes. GHK-Cu is prescription-only. The free online assessment takes about five minutes, a physician licensed in your state reviews it within 4 hours, and if approved the prescription goes to the pharmacy. If not approved, the medication charge is refunded.
No. GHK-Cu can be prescribed from the assessment alone. Bloodwork is required only for the GLP-1s and growth-hormone secretagogues, and the intake tells you if a medication on your order needs it.
GHK-Cu is a subcutaneous injection into the abdomen or thigh with a small insulin syringe. Your kit ships with sterile syringes and alcohol prep pads, and the exact dose and schedule are printed on the pharmacy label. Dosing videos are in your account.
33 more questions about Pepti, answered.Show fewer
One vial is your monthly supply at the dose your physician prescribes. A fresh vial ships about every 28 days, and the date moves if your physician changes your dose. Store it as the pharmacy label directs, refrigerated.
Once per fill, $239 each time, when the next vial ships. It renews until you cancel, which you can do anytime from your account with no cancellation fee.
The compounded GHK-Cu with sterile syringes and alcohol prep pads, free tracked shipping in an unbranded box with insulated packaging, the physician review, ongoing physician care and dose adjustments, and unlimited messaging.
Reported side effects of GHK-Cu are usually mild: mild redness or swelling at injection site; temporary fatigue or headache; mild nausea (uncommon). The physician screens your history, medications, and allergies before prescribing, the medication-specific consent lists the known risks, and you can message your physician about anything you notice. Seek emergency care for severe symptoms.
Response varies by person, goal, and dose, and GHK-Cu is prescribed for ongoing use rather than a short trial. Your physician sets expectations at approval, tracks how you respond through your account, and adjusts the dose without an appointment.
Yes. Request it from your account or the app; your physician approves or declines. If approved you pay for the additional medication at the pharmacy's cost and the new dose applies to your next shipment.
Yes. Add GHK-Cu to a plan with another treatment and both go through one assessment and one physician review, shipping together on one schedule. Each keeps its own catalog price. The physician reviews the combination and can adjust it.
No. Compounded GHK-Cu is not FDA-approved. It is prepared to your physician's prescription by a state-licensed, FDA-registered 503A pharmacy and every batch is independently tested before release.
Yes, when prescribed by a licensed physician and dispensed by a licensed pharmacy, which is how Pepti provides it in every state it serves. Research-use-only GHK-Cu sold without a prescription is labeled not for human use and is a different product.
GHK-Cu is a copper peptide that stimulates collagen I and III, elastin, decorin, and glycosaminoglycans. At Pepti it is prescribed to support collagen production, skin repair, hair growth support, wound healing. Individual response varies, and your physician sets expectations at approval.
GHK-Cu is a copper peptide that stimulates collagen I and III, elastin, decorin, and glycosaminoglycans. It promotes hair follicle growth, accelerates wound healing, and drives skin remodeling at the dermal level. Compounded GHK-Cu is not FDA-approved; it is prescribed off-label by a licensed physician after reviewing your assessment.
GHK-Cu is prescribed for collagen production, skin repair, hair growth support, wound healing. It is commonly requested by adults focused on skin quality, collagen, and hair; patients recovering from procedures or wounds their physician is managing; people who want a systemic skin-support peptide rather than a topical. Whether it is appropriate for you is the reviewing physician's decision.
GHK-Cu is studied for collagen production, skin repair, hair growth support, wound healing. Those are the goals it is prescribed to support at Pepti; results vary by person, dose, and consistency, and no outcome is guaranteed. Your physician tracks how you respond through your account.
GHK-Cu is one of the most-studied peptides in dermatology, with over 100 published papers since Pickart's foundational work in the 1970s. Documented effects include collagen synthesis upregulation (Maquart et al., FEBS Lett 1988), accelerated wound healing in diabetic mice (Pickart, Brief Funct Genomics 2017), and gene expression changes consistent with skin regeneration. Pickart & Margolina's 2018 Cosmetics review reported clinical trials showing improvements in skin firmness, elasticity, fine lines, and wound healing. Mechanistically GHK-Cu also modulates antioxidant defenses (SOD, glutathione) and reduces inflammatory cytokines. The peptide is a small ligand that releases copper into cells in a controlled manner, supporting both the structural collagen scaffold and the antioxidant defense system simultaneously. References are listed on this page.
GHK-Cu is generally not prescribed with: active cancer or history of cancer (unless approved by oncologist); pregnancy or breastfeeding; severe kidney or liver disease; known allergy to the peptide or excipients. The physician screens for these in your intake, and anything that rules GHK-Cu out means it is not prescribed and is refunded.
At Pepti. Complete the free assessment, a physician licensed in your state reviews it within 4 hours, and if appropriate GHK-Cu is compounded by a state-licensed, FDA-registered pharmacy and shipped free to your door for $239 per month, all-in. Not prescribed means refunded.
Injectable vial: 10 mL at 10 mg/mL, containing 100 mg GHK-Cu. Injectable vial: 5 mL at 10 mg/mL, containing 50 mg GHK-Cu. One vial is your monthly supply at the prescribed dose, and a fresh one ships about every 28 days.
Not currently. GHK-Cu ships as a multi-dose vial with sterile syringes and prep pads. The pepti Pen is available for 10 other treatments.
$239 per month covers the compounded GHK-Cu, the physician review, ongoing physician care including dose adjustments and refill review, unlimited messaging, and free tracked shipping. There is no membership, consult, visit, or refill fee; the only separate charges are optional at-home lab panels and a physician-approved dose increase billed at pharmacy cost.
Yes. GHK-Cu is on Pepti's live catalog, which lists only treatments a partner pharmacy can compound and ship today. If a physician prescribes it, it ships; if it ever cannot be dispensed, the charge is refunded.
GHK-Cu ships to 50 states, free and tracked, in insulated unbranded packaging. Eligibility is confirmed during the assessment from your shipping address.
$239 per month at Pepti. That includes the compounded GHK-Cu, the physician review and ongoing care, free tracked shipping, and messaging, with no membership, consult, or visit fee. The price is the same in every state and every refill is the same price.
Pepti supplies GHK-Cu as a monthly injectable vial with syringes and prep pads included, one vial per month at $239, prescribed by a licensed physician after a free online assessment and shipped free from a state-licensed, FDA-registered pharmacy in insulated packaging.
Yes. Pepti prescribes GHK-Cu online in 50 states after a free assessment reviewed by a physician licensed in your state. It is compounded by an FDA-registered pharmacy and shipped free, $239 per month all-in. Not prescribed means refunded.
Yes. At Pepti the entire process is telehealth: a five-minute online assessment, physician review within 4 hours, then GHK-Cu ships from the pharmacy. No clinic visit and no video appointment in most cases. $239 per month, all-in.
Yes, for the real thing. GHK-Cu sold without a prescription is research-use-only product labeled not for human use, with no physician, no pharmacy, and no verified testing. Pepti's GHK-Cu is physician-prescribed, pharmacy-compounded, batch-tested, and $239 per month including the physician and shipping.
Pepti does, in 50 states, with named board-certified physicians, a state-licensed FDA-registered compounding pharmacy, independent batch testing, and one published all-in price of $239 per month with no membership or consult fee. Refunded if the physician does not prescribe.
It is legal to be prescribed GHK-Cu online by a licensed physician and have it dispensed by a licensed pharmacy, which is how Pepti provides it. Buying it as a research chemical without a prescription is a different product and is not for human use. Compounded GHK-Cu is not FDA-approved.
$239 per month at Pepti, including the medication, the physician, and shipping. Refills are the same price and there is no membership fee.
Yes. Pepti has no clinics: the assessment, physician review, messaging, dose changes, and refills all happen online, and GHK-Cu ships free from the pharmacy to your door in 50 states.
Start the free assessment at hellopepti.com, choose GHK-Cu, and answer the health questions. A physician licensed in your state reviews it within 4 hours. If approved, GHK-Cu ships within 1-3 business days and arrives in 1-3 more; if not, the $239 is refunded.
No. GHK-Cu can be prescribed from the assessment alone at Pepti. Bloodwork is required only for GLP-1s and growth-hormone secretagogues.
Pepti ships GHK-Cu to 50 states, free and tracked, refrigerated in insulated packaging, directly from the pharmacy. Delivery is 1-3 business days after the pharmacy compounds it.
Questions people ask
about GHK-Cu (Injectable).
- GHK-Cu: What It Is, Where to Get It Prescribed, and What It CostsGHK-Cu — 5 mL multi-dose vial, GHK-Cu 10 mg/mL (50 mg GHK-Cu per vial). Specification, mechanism, dosing, formats, state availability and how to get it prescribed.
- Is GHK-Cu Safe? Copper Load, Side Effects and Who Should Avoid ItWhat is known about GHK-Cu safety: the copper-specific risks, reported side effects, the conditions that rule it out, and the monitoring a physician applies to injectable use.
- Where to Buy GHK-Cu Online: Injectable Prescription vs Serum vs Grey MarketThree different products are sold as GHK-Cu. This explains what GHK-Cu is, which version needs a prescription, how to get the injectable legitimately, what it costs, and the red flags.
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Read more about GHK-Cu (Injectable).
GHK-Cu: What It Is, Where to Get It Prescribed, and What It Costs
GHK-Cu — 5 mL multi-dose vial, GHK-Cu 10 mg/mL (50 mg GHK-Cu per vial). Specification, mechanism, dosing, formats, state availability and how to get it prescribed.
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