Anti-Aging · Reference
Tesamorelin Dosage: How Pepti Prescribes It, in Units, mL and mg
This page explains the tesamorelin dosage Pepti prescribes, what the units on the syringe mean, a dosage chart for tesamorelin and each blend that contains it, when it is taken, what can change your directions, and the side effects to know about. It covers how Pepti prescribes tesamorelin, not online protocols. Nothing here is a reason to change your own dose.
Medically reviewed by Dr. Gene, MD · November 4, 2026
At Pepti, tesamorelin is prescribed as 0.25 mL, which is 25 units on a U-100 insulin syringe, injected under the skin Monday through Friday nights at bedtime. The vial is 5 mL at 2 mg/mL, so each 0.25 mL dose carries 0.5 mg of tesamorelin and the vial holds 20 doses, about four weeks. Your physician sets your directions after reviewing your intake, and your exact dose and units are printed on the vial. Every Pepti blend that contains tesamorelin uses the same 0.25 mL draw and the same 20 doses per vial.
This page explains the tesamorelin dosage Pepti prescribes, what the units on the syringe mean, a dosage chart for tesamorelin and each blend that contains it, when it is taken, what can change your directions, and the side effects to know about. It covers how Pepti prescribes tesamorelin, not online protocols. Nothing here is a reason to change your own dose.
Tesamorelin Dosage
The short answer
| Product | Vial | Directions | Doses per vial | Price |
|---|---|---|---|---|
| Tesamorelin | 5 mL, 2 mg/mL (10 mg per vial) | Inject 0.25 mL (25 units) subcutaneously Monday through Friday nights at bedtime | 20 | $249/mo |
| Tesamorelin + Ipamorelin | 5 mL, tesamorelin 2 mg/mL + ipamorelin 1 mg/mL | Inject 0.25 mL (25 units) subcutaneously Monday through Friday nights at bedtime | 20 | $259/mo |
Every price is all-in, covering medication, physician review, refill management and shipping, with no separate membership fee. Pepti is cash-pay and does not bill insurance. Your own directions are the ones printed on your vial.
Tesamorelin Dosage
Tesamorelin dosage in units, mL and mg
Pepti's directions are written in two forms, millilitres and units, because prescriptions are written in millilitres and insulin syringes are marked in units. On a U-100 insulin syringe, 1 unit is 0.01 mL, so 100 units is 1 mL and 25 units is 0.25 mL. A unit is a volume mark on the barrel, not a measure of how strong the medication is.
The milligram figure comes from the concentration on the label. Tesamorelin is supplied at 2 mg/mL, so:
| What you read | Value | Where it comes from |
|---|---|---|
| Dose volume | 0.25 mL | Printed on the vial |
| On a U-100 insulin syringe | 25 units | 0.25 mL x 100 units per mL |
| Concentration | 2 mg/mL | Printed on the vial |
| Tesamorelin per dose | 0.5 mg | 2 mg/mL x 0.25 mL |
| Total in the vial | 10 mg in 5 mL | Printed on the vial |
| Doses per vial | 20 | 5 mL divided by 0.25 mL |
That arithmetic is a way to read a label, not a way to set a dose. A vial labelled 10 mg is not a 10 mg dose: it is twenty 0.5 mg doses. If your label and your syringe seem to disagree, do not dose; message your care team. How long does a peptide vial last explains every number on a vial label in more detail.
Tesamorelin Dosage
Tesamorelin dosage chart: every Pepti product that contains it
Tesamorelin appears in several Pepti blends. Each one is a 5 mL vial drawn at 0.25 mL, 20 doses per vial. The timing differs: some are directed at bedtime, some once daily on weekdays without a stated time. The tesamorelin per dose is computed from each vial's concentration.
| Product | Tesamorelin per vial | Directions | Tesamorelin per dose | Doses per vial | Price |
|---|---|---|---|---|---|
| Tesamorelin | 10 mg (2 mg/mL) | 0.25 mL (25 units) Monday through Friday nights at bedtime | 0.5 mg | 20 | $249/mo |
| Tesamorelin + Ipamorelin | 10 mg (2 mg/mL), with 5 mg ipamorelin | 0.25 mL (25 units) Monday through Friday nights at bedtime | 0.5 mg | 20 | $259/mo |
| PHYSIQ Blend | 10 mg (2 mg/mL), with ipamorelin, AOD-9604 and MOTS-c | 0.25 mL (25 units) Monday through Friday nights at bedtime | 0.5 mg | 20 | $289/mo |
| TITAN Blend | 10 mg (2 mg/mL), with CJC-1295, ipamorelin and BPC-157 | 0.25 mL (25 units) Monday through Friday nights at bedtime | 0.5 mg | 20 | $289/mo |
| ASCEND Blend | 10 mg (2 mg/mL), with CJC-1295, ipamorelin and IGF-1 LR3 | 0.25 mL (25 units) Monday through Friday nights at bedtime | 0.5 mg | 20 | $289/mo |
| RADIANCE Blend | 10 mg (2 mg/mL), with GHK-Cu | 0.25 mL (25 units) once daily Monday through Friday | 0.5 mg | 20 | $249/mo |
| SYNAPSE Blend | 10 mg (2 mg/mL), with semax, selank and MOTS-c | 0.25 mL (25 units) once daily Monday through Friday | 0.5 mg | 20 | $279/mo |
| FUSION Blend | 15 mg (3 mg/mL), with BPC-157, MOTS-c and 5-Amino-1MQ | 0.25 mL (25 units) once daily Monday through Friday | 0.75 mg | 20 | $279/mo |
Two things stand out. First, the volume never changes: every product in the chart is 25 units. Second, FUSION is the one blend where the same 25 units carries more tesamorelin, because its vial is more concentrated. That is why you read your own label rather than a chart, including this one.
In a blend, every ingredient is in fixed proportion. One 0.25 mL draw delivers all of them in the ratio the pharmacy compounded. There is no way to take more tesamorelin and less of something else from the same vial; if a different balance is wanted, that is a different prescription. More on the blends is in what is tesamorelin + ipamorelin and physiq vs shred vs titan.
Tesamorelin Dosage
When tesamorelin is taken
At bedtime
Pepti's tesamorelin directions say nights at bedtime. The body's largest natural growth hormone pulse occurs during slow-wave sleep, and tesamorelin prompts the pituitary to release your own growth hormone. Dosing shortly before sleep places that signal on top of a pulse the body is already producing. That is the reason the label says bedtime.
Monday through Friday
The weekday schedule, with weekends off, is a prescriber convention rather than something derived from trials. Prescribers describe the two nights off as keeping the pituitary responsive. It also makes the arithmetic clean: 20 doses at five a week is exactly four weeks.
Under the skin
Subcutaneous means into the fat layer, not the muscle. The abdomen is the usual site, rotated so the same spot is not used repeatedly. Technique is covered in how to inject peptides safely.
Directions say What it means in practice 0.25 mL (25 units) Draw to the 25 mark on a U-100 insulin syringe Subcutaneously Into the fat layer, usually the abdomen, rotating sites Monday through Friday Five doses a week, weekends off Nights at bedtime Shortly before sleep 20 doses per vial About four weeks, then the next refill
Tesamorelin Dosage
How a vial maps onto refills
Each vial is sized to last about four weeks at the printed directions, which is why refills run every 28 days, one vial per fill. Vials are multi-dose solutions shipped ready to use, refrigerated with ice packs, with sterile syringes and alcohol prep pads. Nothing is mixed at home. Keep the vial in the fridge, and follow the beyond-use date printed on the label, which runs from first puncture. How to store peptides covers storage.
If a vial runs short before the refill, message your care team rather than adjusting anything yourself. If you miss a weekday dose, follow your directions and do not take two doses to make up for one.
Tesamorelin Dosage
What changes the directions
Your physician sets your directions after reviewing your intake. Things that can lead to different directions, or a different product, include:
| What can change | How it shows up |
|---|---|
| Which product is prescribed | Tesamorelin alone, tesamorelin + ipamorelin, or a blend; each has its own label |
| Your medical history | Diabetes or a borderline glucose, a pituitary condition, or a cancer history change the conversation; see the cautions below |
| Your other medications | The intake asks for everything you take, because growth hormone can alter how some drugs are metabolised |
| How you respond | Side effects you report, such as puffiness or hand tingling, go to your physician, who may revise your directions |
When directions change, the new numbers are printed on the new label. Never carry a number over from a previous fill. If your physician wants labs for your care, they'll ask through your account; bloodwork is not required for any Pepti treatment.
Tesamorelin Dosage
Side effects, in summary
The full picture, with the figures from the approved product's label, is in tesamorelin benefits. Those label figures were recorded at a higher daily dose than Pepti's compounded directions.
| What is reported | What it usually means | What to do |
|---|---|---|
| Injection-site redness, itching or a small lump | The commonest complaint | Rotate sites |
| Puffiness, joint aches, hand tingling | Classic growth hormone effects | Message your care team; do not change the dose yourself |
| Raised blood sugar | Growth hormone reduces insulin sensitivity | Raise diabetes or borderline glucose at intake |
| Itching, flushing, hives or rash | Hypersensitivity | Report it; emergency care for throat swelling or breathing difficulty |
Who should not take tesamorelin, or should discuss it first: anyone with a pituitary disorder, pituitary surgery, head irradiation or head trauma; anyone with an active cancer; anyone pregnant or breastfeeding; anyone with a known hypersensitivity to tesamorelin. Tested athletes should know the 2026 WADA Prohibited List names tesamorelin under S2.2.4, prohibited at all times.
An approved tesamorelin product exists for one specific indication. Compounded tesamorelin prescribed for other uses is not FDA approved, and compounded medications are not FDA approved.
Tesamorelin Dosage
Where to get tesamorelin prescribed
Tesamorelin cannot be bought legitimately without a prescription. Sites selling it "for research use only" are not accountable for what is in the vial: identity, purity, sterility and concentration are untested. The prescription route:
- Complete a free online intake covering your history, medications and what you want help with.
- A physician licensed in your state reviews it, usually within 24 hours.
- If it is appropriate, a PCAB-accredited, FDA-registered US 503A compounding pharmacy prepares it to that prescription. Lot test results are published at /quality/lab-results.
- It ships refrigerated with your directions printed on the vial.
- Your physician stays reachable for questions and dose changes.
Pepti prescribes tesamorelin in all 50 states and DC. Step by step: how to get tesamorelin prescribed online. How it compares with neighbouring products: sermorelin vs tesamorelin vs ipamorelin and AOD-9604 vs tesamorelin.
References
What this is based on.
References
- Falutz J, Allas S, Blot K et al.. Metabolic effects of a growth hormone-releasing factor in patients with HIV · N Engl J Med (2007) · PMID 18057338
- Stanley TL, Feldpausch MN, Oh J et al.. Effect of tesamorelin on visceral fat and liver fat in HIV-infected patients with abdominal fat accumulation: a randomized clinical trial · JAMA (2014) · PMID 25038357
- Falutz J, Mamputu JC, Potvin D et al.. Effects of tesamorelin (TH9507), a growth hormone-releasing factor analog, in human immunodeficiency virus-infected patients with excess abdominal fat: a pooled analysis of two multicenter, double-blind placebo-controlled phase 3 trials with safety extension data · J Clin Endocrinol Metab (2010) · PMID 20554713
- Falutz J, Potvin D, Mamputu JC et al.. Effects of tesamorelin, a growth hormone-releasing factor, in HIV-infected patients with abdominal fat accumulation: a randomized placebo-controlled trial with a safety extension · J Acquir Immune Defic Syndr (2010) · PMID 20101189
- Stanley TL, Fourman LT, Feldpausch MN et al.. Effects of tesamorelin on non-alcoholic fatty liver disease in HIV: a randomised, double-blind, multicentre trial · Lancet HIV (2019) · PMID 31611038
- Makimura H, Feldpausch MN, Rope AM et al.. Metabolic effects of a growth hormone-releasing factor in obese subjects with reduced growth hormone secretion: a randomized controlled trial · J Clin Endocrinol Metab (2012) · PMID 23015655
- Dal J, Leisner MZ, Hermansen K et al.. Cancer Incidence in Patients With Acromegaly: A Cohort Study and Meta-Analysis of the Literature · J Clin Endocrinol Metab (2018) · PMID 29590449
- Johannsson G, Touraine P, Feldt-Rasmussen U et al.. Long-term Safety of Growth Hormone in Adults With Growth Hormone Deficiency: Overview of 15 809 GH-Treated Patients · J Clin Endocrinol Metab (2022) · PMID 35368070
- Zhou H, Sun L, Zhang S, Wang Y, Wang G. Effect of long-term growth hormone replacement on glucose metabolism in adults with growth hormone deficiency: a systematic review and meta-analysis · Pituitary (2021) · PMID 32888174
- Clemmons DR. Roles of insulin-like growth factor-I and growth hormone in mediating insulin resistance in acromegaly · Pituitary (2002) · PMID 12812310
- Clemmons DR. Consensus statement on the standardization and evaluation of growth hormone and insulin-like growth factor assays · Clinical Chemistry (2011) · PMID 21285256
- Liu H, Bravata DM, Olkin I, Nayak S, Roberts B. Systematic review: the safety and efficacy of growth hormone in the healthy elderly · Annals of Internal Medicine (2007) · PMID 17227934
Citations are provided for educational purposes. They do not constitute medical advice. Always discuss any peptide protocol with your prescribing physician.
Common questions
Tesamorelin Dosage, answered.
At Pepti, 0.25 mL, which is 25 units on a U-100 insulin syringe, injected subcutaneously Monday through Friday nights at bedtime. From the 2 mg/mL vial that is 0.5 mg per dose. Your physician sets your directions after reviewing your intake, and your exact dose is printed on the vial.
The number printed on your vial. Pepti's standard directions are 25 units, which is 0.25 mL on a U-100 insulin syringe, where 1 unit is 0.01 mL.
From a 2 mg/mL vial, 0.5 mg. From the FUSION Blend, which holds tesamorelin at 3 mg/mL, the same 25 units carries 0.75 mg.
The chart above lists every Pepti product that contains tesamorelin, with its directions, tesamorelin per dose and doses per vial. All of them are 25 units, 20 doses per vial. Your own label is the one that applies.
Twenty. A 5 mL vial divided by 0.25 mL per dose is 20 doses, about four weeks at five nights a week.
Pepti's tesamorelin directions say nights at bedtime, because the body's largest natural growth hormone pulse happens during deep sleep. Some blends that contain tesamorelin are directed once daily on weekdays; follow the timing on your label.
The Monday through Friday schedule is a prescriber convention, described as keeping the pituitary responsive. It also lines each vial up with a 28-day refill.
The volume is the same in every Pepti blend that contains tesamorelin: 0.25 mL, 25 units. The tesamorelin per dose is 0.5 mg in most of them and 0.75 mg in the FUSION Blend, and each blend also delivers its other ingredients in fixed proportion.
No. Take the dose printed on your vial, on the schedule printed on your vial. Side effects such as puffiness and joint aches are associated with growth hormone levels above what a person needs. If you have questions about your dose, message your care team.
No. Pepti vials are multi-dose solutions shipped ready to use, with sterile syringes and alcohol prep pads. Nothing is reconstituted at home.
Bloodwork is not required for any Pepti treatment. If your physician wants labs for your care, they'll ask through your account. The free assessment goes to a physician licensed in your state. A consultation does not guarantee a prescription.
Next step
See what a physician recommends for you.
A licensed physician in your state reviews your intake and decides what is appropriate. A consultation does not guarantee a prescription.