
Sermorelin (Injectable)
Natural GH stimulation
The pepti Pen cartridge for this treatment is sold out right now. The vial is the same medication at our best price.
Choose your strength
Every strength is a 4-week supply. A higher strength means more medication per dose on the same monthly cycle. Your provider confirms the dose at review.
All-in monthly price · 10mg
No membership fee · this is the full price · free shipping · avg 4-week supply
Add in-depth bloodwork
Optional — add a physician-reviewed at-home blood panel to your plan.
Your sex-hormone baseline plus the safety markers that matter on therapy — blood counts, liver and kidney function — from one painless upper-arm device. Matched to your sex (PSA for men; progesterone & FSH for women). No needle, no clinic, physician-reviewed.
This treatment requires licensed provider review and approval. Treatment is not guaranteed. If prescribed, medication is fulfilled by a licensed U.S. pharmacy where permitted by law. Compounded medications are not FDA-approved or FDA-cleared.

Reviewed by Dr. Gene, MD · Board-certified Family Medicine
Every Pepti prescription is reviewed by a licensed U.S. physician before it's dispensed — and only provided if clinically appropriate.
Sermorelin (Injectable)
Stimulates your pituitary gland to naturally produce more growth hormone.
About a 4-week supply supply at the standard prescribed dose — your physician confirms exact dosing.
A licensed US physician reviews your intake and prescribes when appropriate.
Compounded fresh at a US pharmacy and shipped cold-chain to your door.
Every order ships free — medication, physician care and refills, one all-in price.
Amounts shown are per unit. Compounded fresh at a US FDA-registered pharmacy.
Every batch independently tested
Every medication batch dispensed through Pepti is independently tested by a qualified third-party laboratory for applicable quality and safety standards before the pharmacy releases it. Batches are tested to the same standard used by 503B outsourcing facilities.
Confirms the finished preparation is free of viable microorganisms.
Screens for endotoxins that can cause fever or inflammatory reactions.
Verifies the labeled concentration of the active peptide is what is in the vial.
Checks the active peptide against impurities and degradation products.
Confirms the peptide in the vial is the correct molecule.
Confirms the solution sits within the range specified for injection.
Checks the finished vial for visible and sub-visible particles.
Confirms the vial seal holds so sterility is maintained through the beyond-use date.
- Lot 100526-SER-2
Tested 2026-10-07 · Biolink Life Sciences Carolinas
Sterility
Sterile
Endotoxin
<2 EU/mL
Potency
99.9%
- Lot 100526-SER-3
Tested 2026-10-07 · Biolink Life Sciences Carolinas
Sterility
Sterile
Endotoxin
<2 EU/mL
Potency
98.7%
- Lot 092826-SER-2
Tested 2026-09-30 · Biolink Life Sciences Carolinas
Sterility
Sterile
Endotoxin
<2 EU/mL
Potency
99.8%
How Sermorelin is prescribed.
- Adults seeking a physiologic growth-hormone-releasing peptide
- Patients whose priority is sleep and recovery rather than fat reduction
- People starting growth-hormone support for the first time
Your physician decides whether Sermorelin is appropriate for you after reviewing your intake and labs.
Inject 0.25 mL (25 units) subcutaneously Monday through Friday nights.
- Licensed physician review of your intake, history, and labs
- Medication compounded to your prescription by a PCAB-accredited, FDA-registered pharmacy
- Every batch independently tested before release
- Sterile syringes and alcohol prep pads for injectables
- Tracked delivery to your door, refills on schedule
- Message your physician anytime; dose changes without an appointment
- Store refrigerated (36–46°F / 2–8°C) at all times, including before first use.
- One vial is your monthly supply. A fresh vial ships every 28 days on your refill schedule, so you're always well inside the beyond-use date on your label.
- Protect from light. Wipe the stopper with an alcohol pad before every draw.
- Dispose of syringes in the sharps container per the included instructions.
A typical course of Sermorelin.
Everything published
about Sermorelin.
How it is described to work, pathway by pathway. What the research shows and what it does not. Where it stands with the FDA, dated and sourced.
Read the referencepeer-reviewed, each verified on PubMed
mechanism, evidence, dosing, safety, FAQ
2026 · checked against fda.gov, not memory
How Sermorelin works, and what the research shows.
Sermorelin is a GHRH analog that stimulates the pituitary to produce more of its own growth hormone naturally.
Unlike synthetic HGH, sermorelin works with your body's existing feedback loops, making it gentler and more sustainable.
Sermorelin was developed and FDA-approved for pediatric growth hormone deficiency (Geref, 1990s) before falling out of commercial production.
In adults, sermorelin has been studied as a GHRH replacement strategy for somatopause — the age-related decline in pituitary GH secretion.
Walker et al. (Clin Endocrinol 1990s) demonstrated dose-dependent restoration of GH/IGF-1 in older adults.
Because sermorelin works upstream at the pituitary level, it preserves the natural pulsatile pattern of GH release and physiological negative feedback, making it safer than direct HGH replacement for long-term adult use.
References
- Khorram O, Laughlin GA, Yen SS. Endocrine and metabolic effects of long-term administration of [Nle27]growth hormone-releasing hormone-(1-29)-NH2 in age-advanced men and women · The Journal of clinical endocrinology and metabolism (1997) · PMID 9141536
- Vittone J, Blackman MR, Busby-Whitehead J, et al.. Effects of single nightly injections of growth hormone-releasing hormone (GHRH 1-29) in healthy elderly men · Metabolism: clinical and experimental (1997) · PMID 9005976
- Thorner M, Rochiccioli P, Colle M, et al.. Once daily subcutaneous growth hormone-releasing hormone therapy accelerates growth in growth hormone-deficient children during the first year of therapy. Geref International Study Group · Journal of Clinical Endocrinology & Metabolism (1996) · PMID 8772599
- Prakash A, Goa KL. Sermorelin: a review of its use in the diagnosis and treatment of children with idiopathic growth hormone deficiency · BioDrugs (1999) · PMID 18031173
- Corpas E, Harman SM, Piñeyro MA, Roberson R, Blackman MR. Growth hormone (GH)-releasing hormone-(1-29) twice daily reverses the decreased GH and insulin-like growth factor-I levels in old men · Journal of Clinical Endocrinology & Metabolism (1992) · PMID 1379256
- Khorram O, Yeung M, Vu L, Yen SS. Effects of [norleucine27]growth hormone-releasing hormone (GHRH) (1-29)-NH2 administration on the immune system of aging men and women · Journal of Clinical Endocrinology & Metabolism (1997) · PMID 9360512
- Vitiello MV, Moe KE, Merriam GR, et al.. Growth hormone releasing hormone improves the cognition of healthy older adults · Neurobiology of Aging (2006) · PMID 16399214
- Baker LD, Barsness SM, Borson S, et al.. Effects of growth hormone-releasing hormone on cognitive function in adults with mild cognitive impairment and healthy older adults: results of a controlled trial · Archives of Neurology (2012) · PMID 22869065
- Johannsson G, Touraine P, Feldt-Rasmussen U, Pico A, Vila G et al.. Long-term Safety of Growth Hormone in Adults With Growth Hormone Deficiency: Overview of 15 809 GH-Treated Patients · J Clin Endocrinol Metab (2022) · PMID 35368070
- Münzer T, Rosen CJ, Harman SM et al.. Effects of GH and/or sex steroids on circulating IGF-I and IGFBPs in healthy, aged women and men · Am J Physiol Endocrinol Metab (2006) · PMID 16390864
- Roelfsema F, Yang RJ, Takahashi PY et al.. Aromatized Estrogens Amplify Nocturnal Growth Hormone Secretion in Testosterone-Replaced Older Hypogonadal Men · J Clin Endocrinol Metab (2018) · PMID 30032193
- Merriam GR, Schwartz RS, Vitiello MV. Growth hormone-releasing hormone and growth hormone secretagogues in normal aging · Endocrine (2003) · PMID 14610297
- Hersch EC, Merriam GR. Growth hormone (GH)-releasing hormone and GH secretagogues in normal aging: Fountain of Youth or Pool of Tantalus? · Clin Interv Aging (2008) · PMID 18488883
- Sood A, Mohiyiddeen G, Ahmad G, et al.. Growth hormone for in vitro fertilisation (IVF) · Cochrane Database Syst Rev (2021) · PMID 34808697
- Molitch ME, Clemmons DR, Malozowski S, et al.. Evaluation and treatment of adult growth hormone deficiency: an Endocrine Society clinical practice guideline · The Journal of Clinical Endocrinology and Metabolism (2011) · PMID 21602453
- Liu H, Bravata DM, Olkin I, Nayak S, Roberts B. Systematic review: the safety and efficacy of growth hormone in the healthy elderly · Annals of Internal Medicine (2007) · PMID 17227934
- Milman S, Atzmon G, Huffman DM et al.. Low insulin-like growth factor-1 level predicts survival in humans with exceptional longevity · Aging Cell (2014) · PMID 24618355
- Iranmanesh A, Lizarralde G, Veldhuis JD. Age and relative adiposity are specific negative determinants of the frequency and amplitude of growth hormone (GH) secretory bursts and the half-life of endogenous GH in healthy men · J Clin Endocrinol Metab (1991) · PMID 1939523
- Kerkhofs M, Van Cauter E, Van Onderbergen A, Caufriez A et al.. Sleep-promoting effects of growth hormone-releasing hormone in normal men · Am J Physiol (1993) · PMID 8476038
- Steiger A, Guldner J, Hemmeter U, Rothe B et al.. Effects of growth hormone-releasing hormone and somatostatin on sleep EEG and nocturnal hormone secretion in male controls · Neuroendocrinology (1992) · PMID 1361964
- Obál F Jr, Krueger JM. GHRH and sleep · Sleep Med Rev (2004) · PMID 15336237
- Rudman D, Feller AG, Nagraj HS et al.. Effects of human growth hormone in men over 60 years old · N Engl J Med (1990) · PMID 2355952
Citations are provided for educational purposes. They do not constitute medical advice. Always discuss any peptide protocol with your prescribing physician.
Important safety information
+
Possible side effects
Do not use if you have
If you experience severe side effects, call 911 or go to your nearest emergency room.
5 mL multi-dose vial, Sermorelin 2 mg/mL (10 mg Sermorelin per vial); as the Pen: 3 mL pre-filled Pen cartridge containing 9 mg Sermorelin
Frequently asked
about Sermorelin (Injectable).
Stimulates your pituitary gland to naturally produce more growth hormone. Sermorelin is prescription-only at Pepti: a licensed physician reviews your assessment and, if appropriate, prescribes it to be compounded by a state-licensed, FDA-registered pharmacy.
Sermorelin is $229 per month at Pepti as a vial, or $299 as a pre-filled pepti Pen. That is all-in: medication, physician review and ongoing care, shipping, and messaging. No membership, consult, or visit fees, and the price is the same in every state.
Sermorelin is commonly prescribed for: Adults seeking a physiologic growth-hormone-releasing peptide; Patients whose priority is sleep and recovery rather than fat reduction; People starting growth-hormone support for the first time. Whether it is appropriate for you is decided by the reviewing physician from your history, medications, and labs where required.
Yes. Sermorelin is prescription-only. The free online assessment takes about five minutes, a physician licensed in your state reviews it within 4 hours, and if approved the prescription goes to the pharmacy. If not approved, the medication charge is refunded.
Yes. Sermorelin is one of the medications Pepti requires recent bloodwork for before it is prescribed. Upload a recent lab report from any lab, or order Pepti's at-home panel; the physician reviews the results with your assessment.
Sermorelin is a subcutaneous injection into the abdomen or thigh with a small insulin syringe. Your kit ships with sterile syringes and alcohol prep pads, and the exact dose and schedule are printed on the pharmacy label. Dosing videos are in your account. It is also available as a pre-filled pepti Pen for $299.
33 more questions about Pepti, answered.Show fewer
One vial is your monthly supply at the dose your physician prescribes. A fresh vial ships about every 28 days, and the date moves if your physician changes your dose. Store it as the pharmacy label directs, refrigerated.
Once per fill, $229 each time, when the next vial ships. It renews until you cancel, which you can do anytime from your account with no cancellation fee.
The compounded Sermorelin with sterile syringes and alcohol prep pads, free tracked shipping in an unbranded box with insulated packaging, the physician review, ongoing physician care and dose adjustments, and unlimited messaging.
Reported side effects of Sermorelin are usually mild: mild redness or swelling at injection site; temporary fatigue or headache; mild nausea (uncommon). The physician screens your history, medications, and allergies before prescribing, the medication-specific consent lists the known risks, and you can message your physician about anything you notice. Seek emergency care for severe symptoms.
Response varies by person, goal, and dose, and Sermorelin is prescribed for ongoing use rather than a short trial. Your physician sets expectations at approval, tracks how you respond through your account, and adjusts the dose without an appointment.
Yes. Request it from your account or the app; your physician approves or declines. If approved you pay for the additional medication at the pharmacy's cost and the new dose applies to your next shipment.
Yes. Add Sermorelin to a plan with another treatment and both go through one assessment and one physician review, shipping together on one schedule. Each keeps its own catalog price. The physician reviews the combination and can adjust it.
No. Compounded Sermorelin is not FDA-approved. It is prepared to your physician's prescription by a state-licensed, FDA-registered 503A pharmacy and every batch is independently tested before release.
Yes, when prescribed by a licensed physician and dispensed by a licensed pharmacy, which is how Pepti provides it in every state it serves. Research-use-only Sermorelin sold without a prescription is labeled not for human use and is a different product.
Sermorelin is a GHRH analog that stimulates the pituitary to produce more of its own growth hormone naturally. At Pepti it is prescribed to support growth hormone boost, improved sleep, energy levels, skin elasticity. Individual response varies, and your physician sets expectations at approval.
Sermorelin is a GHRH analog that stimulates the pituitary to produce more of its own growth hormone naturally. Unlike synthetic HGH, sermorelin works with your body's existing feedback loops, making it gentler and more sustainable. Compounded Sermorelin is not FDA-approved; it is prescribed off-label by a licensed physician after reviewing your assessment.
Sermorelin is prescribed for growth hormone boost, improved sleep, energy levels, skin elasticity. It is commonly requested by adults seeking a physiologic growth-hormone-releasing peptide; patients whose priority is sleep and recovery rather than fat reduction; people starting growth-hormone support for the first time. Whether it is appropriate for you is the reviewing physician's decision.
Sermorelin is studied for growth hormone boost, improved sleep, energy levels, skin elasticity. Those are the goals it is prescribed to support at Pepti; results vary by person, dose, and consistency, and no outcome is guaranteed. Your physician tracks how you respond through your account.
Sermorelin was developed and FDA-approved for pediatric growth hormone deficiency (Geref, 1990s) before falling out of commercial production. In adults, sermorelin has been studied as a GHRH replacement strategy for somatopause — the age-related decline in pituitary GH secretion. Walker et al. (Clin Endocrinol 1990s) demonstrated dose-dependent restoration of GH/IGF-1 in older adults. Because sermorelin works upstream at the pituitary level, it preserves the natural pulsatile pattern of GH release and physiological negative feedback, making it safer than direct HGH replacement for long-term adult use. References are listed on this page.
Sermorelin is generally not prescribed with: active cancer or history of cancer (unless approved by oncologist); pregnancy or breastfeeding; severe kidney or liver disease; known allergy to the peptide or excipients. The physician screens for these in your intake, and anything that rules Sermorelin out means it is not prescribed and is refunded.
At Pepti. Complete the free assessment, a physician licensed in your state reviews it within 4 hours, and if appropriate Sermorelin is compounded by a state-licensed, FDA-registered pharmacy and shipped free to your door for $229 per month, all-in. Not prescribed means refunded.
Injectable vial: 5 mL at 2 mg/mL, containing 10 mg Sermorelin. Injectable vial: 5 mL at 3 mg/mL, containing 15 mg Sermorelin. Pepti Pen cartridge: 3 mL cartridge (300 units) at 3 mg/mL, containing 9 mg Sermorelin. One vial is your monthly supply at the prescribed dose, and a fresh one ships about every 28 days.
Yes. Sermorelin is available as a pre-filled pepti Pen cartridge for $299 per month, versus $229 as a vial. Same medication, same pharmacy; the reusable injector is free with your first pen order. Choose the format in the cart or ask your physician.
$229 per month covers the compounded Sermorelin, the physician review, ongoing physician care including dose adjustments and refill review, unlimited messaging, and free tracked shipping. There is no membership, consult, visit, or refill fee; the only separate charges are optional at-home lab panels and a physician-approved dose increase billed at pharmacy cost.
Yes. Sermorelin is on Pepti's live catalog, which lists only treatments a partner pharmacy can compound and ship today. If a physician prescribes it, it ships; if it ever cannot be dispensed, the charge is refunded.
Sermorelin ships to 50 states, free and tracked, in insulated unbranded packaging. Eligibility is confirmed during the assessment from your shipping address.
$229 per month at Pepti as a vial, or $299 as a pepti Pen. That includes the compounded Sermorelin, the physician review and ongoing care, free tracked shipping, and messaging, with no membership, consult, or visit fee. The price is the same in every state and every refill is the same price.
Yes. Pepti offers Sermorelin as a pre-filled pepti Pen cartridge for $299 per month, or as a vial for $229. The reusable injector is included free with your first pen order and tips come with every cartridge. Same medication, same pharmacy, physician-prescribed after a free online assessment.
Yes. Pepti prescribes Sermorelin online in 50 states after a free assessment reviewed by a physician licensed in your state. It is compounded by an FDA-registered pharmacy and shipped free, $229 per month all-in. Not prescribed means refunded.
Yes. At Pepti the entire process is telehealth: a five-minute online assessment, recent bloodwork from any lab or an at-home panel, physician review within 4 hours, then Sermorelin ships from the pharmacy. No clinic visit and no video appointment in most cases. $229 per month, all-in.
Yes, for the real thing. Sermorelin sold without a prescription is research-use-only product labeled not for human use, with no physician, no pharmacy, and no verified testing. Pepti's Sermorelin is physician-prescribed, pharmacy-compounded, batch-tested, and $229 per month including the physician and shipping.
Pepti does, in 50 states, with named board-certified physicians, a state-licensed FDA-registered compounding pharmacy, independent batch testing, and one published all-in price of $229 per month with no membership or consult fee. Refunded if the physician does not prescribe.
It is legal to be prescribed Sermorelin online by a licensed physician and have it dispensed by a licensed pharmacy, which is how Pepti provides it. Buying it as a research chemical without a prescription is a different product and is not for human use. Compounded Sermorelin is not FDA-approved.
$229 per month at Pepti, or $299 as a pepti Pen, including the medication, the physician, and shipping. Refills are the same price and there is no membership fee.
Yes. Pepti has no clinics: the assessment, physician review, messaging, dose changes, and refills all happen online, and Sermorelin ships free from the pharmacy to your door in 50 states.
Start the free assessment at hellopepti.com, choose Sermorelin, and answer the health questions and upload recent labs or order the at-home panel. A physician licensed in your state reviews it within 4 hours. If approved, Sermorelin ships within 1-3 business days and arrives in 1-3 more; if not, the $229 is refunded.
Yes. Sermorelin is one of the medications Pepti requires recent bloodwork for. Upload a lab report from any lab, or order a Pepti at-home panel from $129; the physician reviews it with your assessment.
Pepti ships Sermorelin to 50 states, free and tracked, refrigerated in insulated packaging, directly from the pharmacy. Delivery is 1-3 business days after the pharmacy compounds it.
Questions people ask
about Sermorelin (Injectable).
- Sermorelin: What It Is, Where to Get It Prescribed, and What It CostsSermorelin — 5 mL multi-dose vial, Sermorelin 2 mg/mL (10 mg Sermorelin per vial). Specification, mechanism, dosing, formats, state availability and how to get it prescribed.
- Is Sermorelin Safe? Side Effects, Monitoring and Who Should Avoid ItWhat is known about sermorelin safety: why prompting your own growth hormone differs from taking it, the side effects that signal too high a dose, and the labs a physician tracks.
- Where to Buy Sermorelin Online: How the Prescription Route WorksSermorelin is prescription-only. This covers what it is, how online prescribing works, why labs come first, what it costs, and the red flags that mark a storefront.
- CJC-1295 vs Sermorelin: Duration, Dosing, Cost and Which to ChooseA head-to-head comparison of the two GHRH analogues: how each works, how long each lasts, what they are paired with, the side-effect profile, price, and who suits which.
- Peptides for Longevity and Anti-Aging: What Is Actually Prescribed and What the Evidence SaysThe peptides used in longevity protocols, what each one does at the cellular level, which claims outrun the evidence, and what it costs.
- How Much Do Peptides Cost? Real Monthly Prices and What Drives ThemWhat prescription peptides actually cost per month, why single molecules price differently from four-peptide blends, which costs providers hide behind a low headline, and how to compare.
Read more about Sermorelin (Injectable).
CJC-1295 / Ipamorelin / Sermorelin: What It Is, Where to Get It Prescribed, and What It Costs
CJC-1295 / Ipamorelin / Sermorelin — Pen only — 3 mL pre-filled Pen cartridge containing 1.5 mg CJC-1295 + 6 mg Ipamorelin + 6 mg Sermorelin (no vial version). Specification, mechanism, dosing, formats, state availability and how to get it prescribed.
Ipamorelin + Sermorelin: What It Is, Where to Get It Prescribed, and What It Costs
Ipamorelin + Sermorelin — 5 mL multi-dose vial, Ipamorelin 2 mg/mL + Sermorelin 2 mg/mL (10 mg Ipamorelin / 10 mg Sermorelin per vial). Specification, mechanism, dosing, formats, state availability and how to get it prescribed.
Sermorelin: What It Is, Where to Get It Prescribed, and What It Costs
Sermorelin — 5 mL multi-dose vial, Sermorelin 2 mg/mL (10 mg Sermorelin per vial). Specification, mechanism, dosing, formats, state availability and how to get it prescribed.
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