“I noticed I felt more rested in the morning after starting Ipamorelin + Sermorelin.”

Ipamorelin + Sermorelin (Injectable)
GH-releasing pair
All-in monthly price
No membership fee · this is the full price · free shipping · avg 4-week supply
Add in-depth bloodwork
Optional — add a physician-reviewed at-home blood panel to your plan.
Your sex-hormone baseline plus the safety markers that matter on therapy — blood counts, liver and kidney function — from one painless upper-arm device. Matched to your sex (PSA for men; progesterone & FSH for women). No needle, no clinic, physician-reviewed.
This treatment requires licensed provider review and approval. Treatment is not guaranteed. If prescribed, medication is fulfilled by a licensed U.S. pharmacy where permitted by law. Compounded medications are not FDA-approved or FDA-cleared.

Reviewed by Dr. Gene, MD · Board-certified Family Medicine
Every Pepti prescription is reviewed by a licensed U.S. physician before it's dispensed — and only provided if clinically appropriate.
FDA status: Compounded medication, not FDA-approved. A blend of Ipamorelin, Sermorelin; no FDA-approved drug combines them. Status of every medication
What patients say about Ipamorelin + Sermorelin
“I made breakfast before work instead of hitting snooze again.”
“I didn’t feel like I needed to sleep half the weekend away.”
“I still woke up some nights, but I felt less groggy getting up.”
Ipamorelin + Sermorelin (Injectable)
Ipamorelin and sermorelin both prompt the body to release its own growth hormone, through two different signals. Together they are a common choice for better sleep, faster recovery and a leaner body. Compounded; not FDA-approved.
About a 4-week supply supply at the standard prescribed dose — your physician confirms exact dosing.
A licensed US physician reviews your intake and prescribes when appropriate.
Compounded fresh at a US pharmacy and shipped cold-chain to your door.
Every order ships free — medication, physician care and refills, one all-in price.
Amounts shown are per unit. Compounded fresh at a US FDA-registered pharmacy.
Every batch independently tested
Every medication batch dispensed through Pepti is independently tested by a qualified third-party laboratory for applicable quality and safety standards before the pharmacy releases it. Batches are tested to the same standard used by 503B outsourcing facilities.
Confirms the finished preparation is free of viable microorganisms.
Screens for endotoxins that can cause fever or inflammatory reactions.
Verifies the labeled concentration of the active peptide is what is in the vial.
How Ipamorelin + Sermorelin is prescribed.
- Adults who sleep poorly and wake up unrecovered
- People over 35 who want a leaner body and faster recovery without hormone replacement
- Patients starting their first growth-hormone peptide who want a gentle option
- Anyone who found CJC-1295 too strong or wants a lighter alternative
Your physician decides whether Ipamorelin + Sermorelin is appropriate for you after reviewing your intake and labs.
Inject 0.25 mL (25 units) subcutaneously Monday through Friday nights at bedtime.
- Licensed physician review of your intake, history, and labs
- Medication compounded to your prescription by a PCAB-accredited, FDA-registered pharmacy
- Every batch independently tested before release
- Sterile syringes and alcohol prep pads for injectables
- Tracked delivery to your door, refills on schedule
- Message your physician anytime; dose changes without an appointment
- Store refrigerated (36–46°F / 2–8°C) at all times, including before first use.
- One vial is your monthly supply. A fresh vial ships every 28 days on your refill schedule, so you're always well inside the beyond-use date on your label.
- Protect from light. Wipe the stopper with an alcohol pad before every draw.
- Dispose of syringes in the sharps container per the included instructions.
A typical course of Ipamorelin + Sermorelin.
Everything published
about Ipamorelin + Sermorelin.
How it is described to work, pathway by pathway. What the research shows and what it does not. Where it stands with the FDA, dated and sourced.
Read the referencepeer-reviewed, each verified on PubMed
mechanism, evidence, dosing, safety, FAQ
2026 · checked against fda.gov, not memory
How Ipamorelin + Sermorelin works, and what the research shows.
Sermorelin copies the brain's own growth-hormone-releasing signal; ipamorelin copies the hunger hormone's signal.
Each tells the pituitary gland to release growth hormone, and together they produce a larger, more natural nighttime pulse without raising stress hormones.
Sermorelin has adult studies showing higher growth hormone and IGF-1 levels and was once approved for children with growth-hormone deficiency; ipamorelin's clean, selective action was shown in 1998 (Raun and colleagues).
The pair has not been trialed together.
References
- Raun K, Hansen BS, Johansen NL et al.. Ipamorelin, the first selective growth hormone secretagogue · Eur J Endocrinol (1998) · PMID 9849822
- Walker RF. Sermorelin: a better approach to management of adult-onset growth hormone insufficiency? · Clin Interv Aging (2006) · PMID 18046908
- Tiulpakov AN, Brook CG, Pringle PJ et al.. GH responses to intravenous bolus infusions of GH releasing hormone and GH releasing peptide 2 separately and in combination in adult volunteers · Clin Endocrinol (Oxf) (1995) · PMID 7586605
- Sigalos JT, Pastuszak AW. The Safety and Efficacy of Growth Hormone Secretagogues · Sex Med Rev (2018) · PMID 28400207
Citations are provided for educational purposes. They do not constitute medical advice. Always discuss any peptide protocol with your prescribing physician.
Important safety information
+
Possible side effects
Do not use if you have
If you experience severe side effects, call 911 or go to your nearest emergency room.
5 mL multi-dose vial, Ipamorelin 2 mg/mL + Sermorelin 2 mg/mL (10 mg Ipamorelin / 10 mg Sermorelin per vial)
Frequently asked
about Ipamorelin + Sermorelin (Injectable).
Ipamorelin and sermorelin both prompt the body to release its own growth hormone, through two different signals. Together they are a common choice for better sleep, faster recovery and a leaner body. Compounded; not FDA-approved. Ipamorelin + Sermorelin is prescription-only at Pepti: a licensed physician reviews your assessment and, if appropriate, prescribes it to be compounded by a state-licensed, FDA-registered pharmacy.
Ipamorelin + Sermorelin is $219 per month at Pepti. That is all-in: medication, physician review and ongoing care, shipping, and messaging. No membership, consult, or visit fees, and the price is the same in every state.
Ipamorelin + Sermorelin is commonly prescribed for: Adults who sleep poorly and wake up unrecovered; People over 35 who want a leaner body and faster recovery without hormone replacement; Patients starting their first growth-hormone peptide who want a gentle option; Anyone who found CJC-1295 too strong or wants a lighter alternative. Whether it is appropriate for you is decided by the reviewing physician from your history, medications, and labs where required.
Yes. Ipamorelin + Sermorelin is prescription-only. The free online assessment takes about five minutes, a physician licensed in your state reviews it within 4 hours, and if approved the prescription goes to the pharmacy. If not approved, the medication charge is refunded.
No. Ipamorelin + Sermorelin can be prescribed from the assessment alone. If your physician wants labs for your care, they'll ask through your account; upload a recent lab report from any lab at no charge, or order Pepti's at-home panel.
Ipamorelin + Sermorelin is a subcutaneous injection into the abdomen or thigh with a small insulin syringe. Your kit ships with sterile syringes and alcohol prep pads, and the exact dose and schedule are printed on the pharmacy label. Dosing videos are in your account.
33 more questions about Pepti, answered.Show fewer
One vial is your monthly supply at the dose your physician prescribes. A fresh vial ships about every 28 days, and the date moves if your physician changes your dose. Store it as the pharmacy label directs, refrigerated.
Once per fill, $219 each time, when the next vial ships. It renews until you cancel, which you can do anytime from your account with no cancellation fee.
The compounded Ipamorelin + Sermorelin with sterile syringes and alcohol prep pads, free tracked shipping in an unbranded box with insulated packaging, the physician review, ongoing physician care and dose adjustments, and unlimited messaging.
Reported side effects of Ipamorelin + Sermorelin are usually mild: mild redness or swelling at injection site; temporary fatigue or headache; mild nausea (uncommon). The physician screens your history, medications, and allergies before prescribing, the medication-specific consent lists the known risks, and you can message your physician about anything you notice. Seek emergency care for severe symptoms.
Response varies by person, goal, and dose, and Ipamorelin + Sermorelin is prescribed for ongoing use rather than a short trial. Your physician sets expectations at approval, tracks how you respond through your account, and adjusts the dose without an appointment.
Yes. Request it from your account or the app; your physician approves or declines. If approved you pay for the additional medication at the pharmacy's cost and the new dose applies to your next shipment.
Yes. Add Ipamorelin + Sermorelin to a plan with another treatment and both go through one assessment and one physician review, shipping together on one schedule. Each keeps its own catalog price. The physician reviews the combination and can adjust it.
No. Compounded Ipamorelin + Sermorelin is not FDA-approved. It is prepared to your physician's prescription by a state-licensed, FDA-registered 503A pharmacy and every batch is independently tested before release.
Yes, when prescribed by a licensed physician and dispensed by a licensed pharmacy, which is how Pepti provides it in every state it serves. Research-use-only Ipamorelin + Sermorelin sold without a prescription is labeled not for human use and is a different product.
Sermorelin copies the brain's own growth-hormone-releasing signal; ipamorelin copies the hunger hormone's signal. At Pepti it is prescribed to support two growth-hormone signals in one vial, deeper sleep support, recovery and lean muscle, nightly injection, monday to friday. Individual response varies, and your physician sets expectations at approval.
Sermorelin copies the brain's own growth-hormone-releasing signal; ipamorelin copies the hunger hormone's signal. Each tells the pituitary gland to release growth hormone, and together they produce a larger, more natural nighttime pulse without raising stress hormones. Compounded Ipamorelin + Sermorelin is not FDA-approved; it is prescribed off-label by a licensed physician after reviewing your assessment.
Ipamorelin + Sermorelin is prescribed for two growth-hormone signals in one vial, deeper sleep support, recovery and lean muscle, nightly injection, monday to friday. It is commonly requested by adults who sleep poorly and wake up unrecovered; people over 35 who want a leaner body and faster recovery without hormone replacement; patients starting their first growth-hormone peptide who want a gentle option; Anyone who found CJC-1295 too strong or wants a lighter alternative. Whether it is appropriate for you is the reviewing physician's decision.
Ipamorelin + Sermorelin is studied for two growth-hormone signals in one vial, deeper sleep support, recovery and lean muscle, nightly injection, monday to friday. Those are the goals it is prescribed to support at Pepti; results vary by person, dose, and consistency, and no outcome is guaranteed. Your physician tracks how you respond through your account.
Sermorelin has adult studies showing higher growth hormone and IGF-1 levels and was once approved for children with growth-hormone deficiency; ipamorelin's clean, selective action was shown in 1998 (Raun and colleagues). The pair has not been trialed together. References are listed on this page.
Ipamorelin + Sermorelin is generally not prescribed with: active cancer or history of cancer (unless approved by oncologist); pregnancy or breastfeeding; severe kidney or liver disease; known allergy to the peptide or excipients. The physician screens for these in your intake, and anything that rules Ipamorelin + Sermorelin out means it is not prescribed and is refunded.
At Pepti. Complete the free assessment, a physician licensed in your state reviews it within 4 hours, and if appropriate Ipamorelin + Sermorelin is compounded by a state-licensed, FDA-registered pharmacy and shipped free to your door for $219 per month, all-in. Not prescribed means refunded.
Injectable vial: 5 mL, containing 10 mg Ipamorelin + 10 mg Sermorelin. One vial is your monthly supply at the prescribed dose, and a fresh one ships about every 28 days.
Not currently. Ipamorelin + Sermorelin ships as a multi-dose vial with sterile syringes and prep pads. The pepti Pen is available for 24 other treatments.
$219 per month covers the compounded Ipamorelin + Sermorelin, the physician review, ongoing physician care including dose adjustments and refill review, unlimited messaging, and free tracked shipping. There is no membership, consult, visit, or refill fee; the only separate charges are optional at-home lab panels and a physician-approved dose increase billed at pharmacy cost.
Yes. Ipamorelin + Sermorelin is on Pepti's live catalog, which lists only treatments a partner pharmacy can compound and ship today. If a physician prescribes it, it ships; if it ever cannot be dispensed, the charge is refunded.
Ipamorelin + Sermorelin ships to 49 states and Washington, D.C, free and tracked, in insulated unbranded packaging. Eligibility is confirmed during the assessment from your shipping address.
$219 per month at Pepti. That includes the compounded Ipamorelin + Sermorelin, the physician review and ongoing care, free tracked shipping, and messaging, with no membership, consult, or visit fee. The price is the same in every state and every refill is the same price.
Pepti supplies Ipamorelin + Sermorelin as a monthly injectable vial with syringes and prep pads included, one vial per month at $219, prescribed by a licensed physician after a free online assessment and shipped free from a state-licensed, FDA-registered pharmacy in insulated packaging.
Yes. Pepti prescribes Ipamorelin + Sermorelin online in 49 states and Washington, D.C after a free assessment reviewed by a physician licensed in your state. It is compounded by an FDA-registered pharmacy and shipped free, $219 per month all-in. Not prescribed means refunded.
Yes. At Pepti the entire process is telehealth: a five-minute online assessment, physician review within 4 hours, then Ipamorelin + Sermorelin ships from the pharmacy. No clinic visit and no video appointment in most cases. $219 per month, all-in.
Yes, for the real thing. Ipamorelin + Sermorelin sold without a prescription is research-use-only product labeled not for human use, with no physician, no pharmacy, and no verified testing. Pepti's Ipamorelin + Sermorelin is physician-prescribed, pharmacy-compounded, batch-tested, and $219 per month including the physician and shipping.
Pepti does, in 49 states and Washington, D.C, with named board-certified physicians, a state-licensed FDA-registered compounding pharmacy, independent batch testing, and one published all-in price of $219 per month with no membership or consult fee. Refunded if the physician does not prescribe.
It is legal to be prescribed Ipamorelin + Sermorelin online by a licensed physician and have it dispensed by a licensed pharmacy, which is how Pepti provides it. Buying it as a research chemical without a prescription is a different product and is not for human use. Compounded Ipamorelin + Sermorelin is not FDA-approved.
$219 per month at Pepti, including the medication, the physician, and shipping. Refills are the same price and there is no membership fee.
Yes. Pepti has no clinics: the assessment, physician review, messaging, dose changes, and refills all happen online, and Ipamorelin + Sermorelin ships free from the pharmacy to your door in 49 states and Washington, D.C.
Start the free assessment at hellopepti.com, choose Ipamorelin + Sermorelin, and answer the health questions. A physician licensed in your state reviews it within 4 hours. If approved, Ipamorelin + Sermorelin ships the next business day and arrives overnight; if not, the $219 is refunded.
No. Ipamorelin + Sermorelin can be prescribed from the assessment alone at Pepti. If your physician wants labs for your care, they'll ask through your account; upload a lab report from any lab, or order a Pepti at-home panel from $129.
Pepti ships Ipamorelin + Sermorelin to 49 states and Washington, D.C, free and tracked, refrigerated in insulated packaging, directly from the pharmacy. It ships the next business day and arrives overnight.
Questions people ask
about Ipamorelin + Sermorelin (Injectable).
- Ipamorelin + Sermorelin: What It Is, Where to Get It Prescribed, and What It CostsIpamorelin + Sermorelin — 5 mL multi-dose vial, Ipamorelin 2 mg/mL + Sermorelin 2 mg/mL (10 mg Ipamorelin / 10 mg Sermorelin per vial). Specification, mechanism, dosing, formats, state availability and how to get it prescribed.
- Is Sermorelin Safe? Side Effects, Monitoring and Who Should Avoid ItWhat is known about sermorelin safety: why prompting your own growth hormone differs from taking it, the side effects that signal too high a dose, and the labs a physician tracks.
- Where to Buy Sermorelin Online: How the Prescription Route WorksSermorelin is prescription-only. This covers what it is, how online prescribing works, why labs come first, what it costs, and the red flags that mark a storefront.
- CJC-1295 vs Sermorelin: Duration, Dosing, Cost and Which to ChooseA head-to-head comparison of the two GHRH analogues: how each works, how long each lasts, what they are paired with, the side-effect profile, price, and who suits which.
- Ipamorelin + Sermorelin Dosage: Units, mL and mg for the IPA Sermorelin VialThe ipamorelin + sermorelin dosage Pepti prescribes: 0.25 mL (25 units on a U-100 insulin syringe) under the skin Monday through Friday nights at bedtime, delivering 0.5 mg of each peptide, 20 doses per vial. Includes a two-peptide units chart, how it compares with the single vials, what the studies used, and side effects.
- Ipamorelin + Sermorelin Side Effects: What Is Reported, Dose Signals, and What to ReportA practical reference to ipamorelin plus sermorelin side effects: flushing, injection-site reactions, headache, hunger and vivid dreams with bedtime dosing, the fluid retention and tingling that signal too much growth hormone, blood sugar, the cancer question, what needs emergency care, and who should not take the IPA Sermorelin vial.
- Ipamorelin + Sermorelin Benefits: What the Research Actually ShowsThe benefits claimed for ipamorelin plus sermorelin, one at a time: a larger growth hormone pulse, IGF-1, the natural pulse pattern, selectivity, sleep, lean mass, skin, recovery and fat loss. What research has looked at for each component, what has never been studied for the pairing, side effects, FDA status and how Pepti supplies the vial.
- Can You Take Ipamorelin + Sermorelin With Tirzepatide or Semaglutide?The Ipamorelin + Sermorelin vial can be prescribed alongside tirzepatide or semaglutide, usually with lean tissue in mind. Why it is paired, the appetite, gastric emptying and glucose points where the two pull in opposite directions, what the evidence does and does not show, how the schedules fit, and what not to stack.
- How Long Does Ipamorelin + Sermorelin Take to Work? What Each Study TimedNo study has timed Ipamorelin + Sermorelin as a blend. What each component's studies measured and for how long: an ipamorelin growth hormone pulse peaking at about 40 minutes, sermorelin's IGF-1 rise within two weeks and fade by sixteen, and why none of it is a timeline for sleep, recovery or body composition.
- Do You Need a Prescription for Ipamorelin + Sermorelin? Is It Legal to Buy Online?Yes, Ipamorelin + Sermorelin needs a prescription. Why the law treats it that way, where each of the two peptides stands with the FDA, what "research use only" vials really are, and what the legal route costs.
- Best Place to Get Ipamorelin + Sermorelin Online: A Provider ChecklistHow to choose where to get Ipamorelin + Sermorelin prescribed online: the checklist that separates a prescription from a research vial, what a fair price includes, and what Pepti's $219 all-in prescription contains.
- How to Get Ipamorelin + Sermorelin Prescribed Online, Step by StepThe five steps to an Ipamorelin + Sermorelin prescription by telehealth: what the intake asks and why, what the physician reviews, what arrives in the box, how the bedtime directions read, and how refills work at $219 a month all-in.
- Ipamorelin + Sermorelin for Women: What the Research Covers, and What It Leaves OutWhat research has looked at for the Ipamorelin + Sermorelin pairing in women: the one sermorelin-class trial that reported women separately, why the ipamorelin human data is in men only, sleep and the menopause transition, pregnancy, cancer history and blood sugar, side effects, and how Pepti supplies the vial.
- Ipamorelin + Sermorelin for Men: What Research in Men Has Looked AtWhat research has looked at for the Ipamorelin + Sermorelin pairing in men: the sermorelin trials in older men, the ipamorelin volunteer study in healthy men, why neither is a testosterone booster, using it alongside TRT, blood sugar, prostate and cancer history, sport, side effects, and how Pepti supplies the vial.
- Where to Get Peptides for Anti-Aging Online: How to Choose a ProviderGHK-Cu, NAD+, epithalon, SS-31 and the growth-hormone-axis peptides are prescription-only. Where to get anti-aging peptides online, what a provider should screen for first, the checklist for choosing one, and what Pepti offers.
- How Much Does Ipamorelin + Sermorelin Cost?Ipamorelin + Sermorelin cost in 2026: $219 per month all-in at Pepti — compounded medication, physician review, and shipping included. No membership or consult fees.
- Best Peptides for Longevity and Anti-AgingTop longevity peptides ranked: NAD+, GHK-Cu, Epitalon, MOTS-c, SS-31. Doctor-prescribed anti-aging protocols based on telomere maintenance, mitochondrial health, and cellular repair.
Read more about Ipamorelin + Sermorelin (Injectable).
Best Place to Get Ipamorelin + Sermorelin Online: A Provider Checklist
How to choose where to get Ipamorelin + Sermorelin prescribed online: the checklist that separates a prescription from a research vial, what a fair price includes, and what Pepti's $219 all-in prescription contains.
Ipamorelin + Sermorelin: What It Is, Where to Get It Prescribed, and What It Costs
Ipamorelin + Sermorelin — 5 mL multi-dose vial, Ipamorelin 2 mg/mL + Sermorelin 2 mg/mL (10 mg Ipamorelin / 10 mg Sermorelin per vial). Specification, mechanism, dosing, formats, state availability and how to get it prescribed.
Ready to start with Ipamorelin + Sermorelin (Injectable)?
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