Melanotan II Dosage: How Pepti Prescribes It, in Units, mL and mg

The price is all-in, covering medication, physician review, refill management and shipping, with no separate membership fee. Pepti is cash-pay and does not bill insurance. Melanotan II is a vial and syringe only; there is no pen. These are the typical printed directions; your own directions are the ones on your vial.

Pepti's directions are written in two forms, millilitres and units, because prescriptions are written in millilitres and insulin syringes are marked in units. On a U-100 insulin syringe, 1 unit is 0.01 mL, so 100 units is 1 mL and 25 units is 0.25 mL. A unit is a volume mark on the barrel, not a measure of how strong the medication is. "Melanotan 2 dosage in units" is one of the most searched questions about this peptide, and the answer is that units only mean something alongside the concentration on the label.

Pepti's Melanotan II is supplied at 2 mg/mL, so:

That arithmetic is a way to read a label, not a way to set a dose. A vial labelled 10 mg is not a 10 mg dose: it is twenty 0.5 mg doses. If your label and your syringe seem to disagree, do not dose; message your care team. How long does a peptide vial last explains every number on a vial label in more detail.

Online Melanotan II charts mix milligrams, micrograms and units, and many are written for powder vials mixed at home to a concentration nobody can check. The chart below is the conversion for Pepti's 2 mg/mL vial, drawn with a U-100 insulin syringe. It is math only. It is not a menu of doses, and the only line that applies to you is the one that matches the number printed on your vial.

The rule behind every row: units divided by 100 gives millilitres, and millilitres multiplied by 2 gives milligrams. A chart from another source, written for a different concentration, gives different milligram figures for the same units. That is the main reason not to dose from a chart, including this one, and the reason the FDA's case reports of toxicity matter: they involved self-sourced product at doses far above any reviewed direction.

At Pepti's typical directions, one 10 mg vial lasts four weeks:

Four weeks is why refills run every 28 days, one vial per fill. Vials are multi-dose solutions shipped ready to use, refrigerated with ice packs, with sterile syringes and alcohol prep pads. Nothing is mixed at home. Keep the vial in the fridge, and follow the beyond-use date printed on the label, which runs from first puncture. How to store peptides covers storage.

If a vial runs short before the refill, message your care team rather than adjusting anything yourself. If you miss a dose, follow your directions and do not take two doses to make up for one.

Melanotan II has a small human literature, all from one research group in the 1990s:

The honest reading: the pigmentation evidence is one three-person, single-blind pilot that showed an effect but was not designed to measure how much, how evenly, or how long it lasts. There are no large randomised trials of Melanotan II and no controlled trials of repeated dosing over weeks or months, which is how it is prescribed. Nothing characterises how dark or how even a result will be for a given person, how long pigmentation persists after stopping, or the long-term safety of repeated courses. Response varies with skin type, baseline pigmentation and sun exposure. That is why your directions come from a physician who has reviewed your intake, not from a study table or a forum.

Melanotan II is not a sunscreen and does not block ultraviolet light; the research does not describe it preventing sunburn or skin cancer. Nothing about it is a reason to use sunbeds or skip sunscreen.

Melanotan II darkens existing moles and freckles. Case reports describe new moles appearing and existing ones changing during use, and a small number describe melanoma diagnosed during or shortly after a course. A 2017 review in the International Journal of Dermatology concluded that a causal link has not been established but that the reports justify caution and skin surveillance.

Your physician sets your directions after reviewing your intake. Things that can lead to different directions, or to Melanotan II not being prescribed, include:

When directions change, the new numbers are printed on the new label. Never carry a number over from a previous fill. Bloodwork is not required for any Pepti treatment. If your physician wants labs for your care, they'll ask through your account.

The full reference is what is Melanotan II. The human studies recorded these, and described them as dose-related and most pronounced at the start:

For any reaction that is severe, spreading, or involves difficulty breathing, stop and contact your physician, and call 911 if it is severe. Melanotan II is not named on the 2026 WADA Prohibited List; tested athletes should check their own sport's current rules. Pregnancy and breastfeeding are exclusions, because safety data is absent.

Most of what is online about Melanotan II's status is out of date. As the FDA's own pages stood when Pepti's references were verified:

So the accurate description today is: no longer flagged in Category 2, scheduled for formal advisory committee review by February 2027, and awaiting that review. It remains legal to prescribe and dispense with a valid prescription. It is not an FDA-approved drug, and compounded medications are not FDA approved. The committee's vote will be advisory; the FDA issues its own determination afterwards. See are peptides FDA approved.

Melanotan II cannot be bought legitimately without a prescription. Sites selling it "for research use only" are not accountable for what is in the vial: identity, purity, sterility and concentration are untested, so even the concentration your units chart depends on is unknown. The prescription route:

1. Complete a free online intake covering your history, medications, skin history and what you want help with.
2. A physician licensed in your state reviews it, usually within 24 hours.
3. If it is appropriate, a PCAB-accredited, FDA-registered US 503A compounding pharmacy prepares it to that prescription. Lot test results are published at /quality/lab-results.
4. It ships refrigerated with your directions printed on the vial, with sterile syringes and alcohol prep pads.
5. Your physician stays reachable for questions and dose changes.

Pepti prescribes Melanotan II in every state except Oklahoma, plus DC Step by step: how to get Melanotan II prescribed online. If the goal is better skin rather than darker skin, peptides for skin covers a different set of products.