Melanotan II (Injectable)
Skin pigmentation & tanning
All-in monthly price
No membership fee · this is the full price · free shipping · avg 4-week supply
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Optional — add a physician-reviewed at-home blood panel to your plan.
Your sex-hormone baseline plus the safety markers that matter on therapy — blood counts, liver and kidney function — from one painless upper-arm device. Matched to your sex (PSA for men; progesterone & FSH for women). No needle, no clinic, physician-reviewed.
This treatment requires licensed provider review and approval. Treatment is not guaranteed. If prescribed, medication is fulfilled by a licensed U.S. pharmacy where permitted by law. Compounded medications are not FDA-approved or FDA-cleared.
Reviewed by Dr. Gene, MD · Board-certified Family Medicine
Every Pepti prescription is reviewed by a licensed U.S. physician before it's dispensed — and only provided if clinically appropriate.
Melanotan II (Injectable)
Stimulates melanocyte production for enhanced skin pigmentation and natural tanning.
About a 4-week supply supply at the standard prescribed dose — your physician confirms exact dosing.
A licensed US physician reviews your intake and prescribes when appropriate.
Compounded fresh at a US pharmacy and shipped cold-chain to your door.
Every order ships free — medication, physician care and refills, one all-in price.
Amounts shown are per unit. Compounded fresh at a US FDA-registered pharmacy.
Every batch independently tested
Every medication batch dispensed through Pepti is independently tested by a qualified third-party laboratory for applicable quality and safety standards before the pharmacy releases it. Batches are tested to the same standard used by 503B outsourcing facilities.
Confirms the finished preparation is free of viable microorganisms.
Screens for endotoxins that can cause fever or inflammatory reactions.
Verifies the labeled concentration of the active peptide is what is in the vial.
Checks the active peptide against impurities and degradation products.
Confirms the peptide in the vial is the correct molecule.
Confirms the solution sits within the range specified for injection.
Checks the finished vial for visible and sub-visible particles.
Confirms the vial seal holds so sterility is maintained through the beyond-use date.
- Lot 100526-MEL-2
Tested 2026-10-07 · Biolink Life Sciences Carolinas
Sterility
Sterile
Endotoxin
<2 EU/mL
Potency
100.1%
- Lot 092826-MEL-2
Tested 2026-09-30 · Biolink Life Sciences Carolinas
Sterility
Sterile
Endotoxin
<2 EU/mL
Potency
99.8%
- Lot 092126-MEL-2
Tested 2026-09-23 · Biolink Life Sciences Carolinas
Sterility
Sterile
Endotoxin
<2 EU/mL
Potency
99.1%
How Melanotan II is prescribed.
- Adults seeking a deeper tan with less sun exposure
- Patients who understand this is not FDA-approved and carries real side effects
Your physician decides whether Melanotan II is appropriate for you after reviewing your intake and labs.
Inject 0.25 mL (25 units) subcutaneously once daily Monday through Friday.
- Licensed physician review of your intake, history, and labs
- Medication compounded to your prescription by a PCAB-accredited, FDA-registered pharmacy
- Every batch independently tested before release
- Sterile syringes and alcohol prep pads for injectables
- Tracked delivery to your door, refills on schedule
- Message your physician anytime; dose changes without an appointment
- Store refrigerated (36–46°F / 2–8°C) at all times, including before first use.
- One vial is your monthly supply. A fresh vial ships every 28 days on your refill schedule, so you're always well inside the beyond-use date on your label.
- Protect from light. Wipe the stopper with an alcohol pad before every draw.
- Dispose of syringes in the sharps container per the included instructions.
A typical course of Melanotan II.
Everything published
about Melanotan II.
How it is described to work, pathway by pathway. What the research shows and what it does not. Where it stands with the FDA, dated and sourced.
Read the referencepeer-reviewed, each verified on PubMed
mechanism, evidence, dosing, safety, FAQ
2026 · checked against fda.gov, not memory
How Melanotan II works, and what the research shows.
Melanotan II is a synthetic analog of alpha-MSH that stimulates melanocytes to produce melanin.
Provides natural-looking pigmentation with minimal UV exposure.
Melanotan II went through early human dose-finding studies in the 1990s at the University of Arizona, demonstrating increased skin pigmentation, and separate small trials showed erectile responses — work that led to the FDA-approved derivative bremelanotide (Vyleesi).
Wessells et al., J Urol 1998Melanotan II itself was never brought through full clinical development, so modern controlled safety and efficacy data are lacking.
References
- Dorr RT, Lines R, Levine N et al.. Evaluation of melanotan-II, a superpotent cyclic melanotropic peptide in a pilot phase-I clinical study · Life Sci (1996) · PMID 8637402
- Wessells H, Fuciarelli K, Hansen J et al.. Synthetic melanotropic peptide initiates erections in men with psychogenic erectile dysfunction: double-blind, placebo controlled crossover study · J Urol (1998) · PMID 9679884
- Wessells H, Gralnek D, Dorr R et al.. Effect of an alpha-melanocyte stimulating hormone analog on penile erection and sexual desire in men with organic erectile dysfunction · Urology (2000) · PMID 11018622
- Wessells H, Levine N, Hadley ME et al.. Melanocortin receptor agonists, penile erection, and sexual motivation: human studies with Melanotan II · Int J Impot Res (2000) · PMID 11035391
- Habbema L, Halk AB, Neumann M, Bergman W. Risks of unregulated use of alpha-melanocyte-stimulating hormone analogues: a review · Int J Dermatol (2017) · PMID 28266027
- Hjuler KF, Lorentzen HF. Melanoma associated with the use of melanotan-II · Dermatology (2014) · PMID 24355990
- Ong S, Bowling J. Melanotan-associated melanoma in situ · Australas J Dermatol (2012) · PMID 22724573
- Nelson ME, Bryant SM, Aks SE. Melanotan II injection resulting in systemic toxicity and rhabdomyolysis · Clin Toxicol (Phila) (2012) · PMID 23121206
- Dreyer BA, Amer T, Fraser M. Melanotan-induced priapism: a hard-earned tan · BMJ Case Rep (2019) · PMID 30796078
- Zhang Y, Collazo R, Gao Y, Li G, Scarpace PJ. Intermittent MTII application evokes repeated anorexia and robust fat and weight loss · Peptides (2010) · PMID 20034526
Citations are provided for educational purposes. They do not constitute medical advice. Always discuss any peptide protocol with your prescribing physician.
Important safety information
+
Possible side effects
Do not use if you have
If you experience severe side effects, call 911 or go to your nearest emergency room.
5 mL multi-dose vial, Melanotan II 2 mg/mL (10 mg Melanotan II per vial)
Frequently asked
about Melanotan II (Injectable).
Stimulates melanocyte production for enhanced skin pigmentation and natural tanning. Melanotan II is prescription-only at Pepti: a licensed physician reviews your assessment and, if appropriate, prescribes it to be compounded by a state-licensed, FDA-registered pharmacy.
Melanotan II is $249 per month at Pepti. That is all-in: medication, physician review and ongoing care, shipping, and messaging. No membership, consult, or visit fees, and the price is the same in every state.
Melanotan II is commonly prescribed for: Adults seeking a deeper tan with less sun exposure; Patients who understand this is not FDA-approved and carries real side effects. Whether it is appropriate for you is decided by the reviewing physician from your history, medications, and labs where required.
Yes. Melanotan II is prescription-only. The free online assessment takes about five minutes, a physician licensed in your state reviews it within 4 hours, and if approved the prescription goes to the pharmacy. If not approved, the medication charge is refunded.
No. Melanotan II can be prescribed from the assessment alone. Bloodwork is required only for the GLP-1s and growth-hormone secretagogues, and the intake tells you if a medication on your order needs it.
Melanotan II is a subcutaneous injection into the abdomen or thigh with a small insulin syringe. Your kit ships with sterile syringes and alcohol prep pads, and the exact dose and schedule are printed on the pharmacy label. Dosing videos are in your account.
33 more questions about Pepti, answered.Show fewer
One vial is your monthly supply at the dose your physician prescribes. A fresh vial ships about every 28 days, and the date moves if your physician changes your dose. Store it as the pharmacy label directs, refrigerated.
Once per fill, $249 each time, when the next vial ships. It renews until you cancel, which you can do anytime from your account with no cancellation fee.
The compounded Melanotan II with sterile syringes and alcohol prep pads, free tracked shipping in an unbranded box with insulated packaging, the physician review, ongoing physician care and dose adjustments, and unlimited messaging.
Reported side effects of Melanotan II are usually mild: mild nausea (first few doses); flushing; new mole development (monitor); increased libido (common). The physician screens your history, medications, and allergies before prescribing, the medication-specific consent lists the known risks, and you can message your physician about anything you notice. Seek emergency care for severe symptoms.
Response varies by person, goal, and dose, and Melanotan II is prescribed for ongoing use rather than a short trial. Your physician sets expectations at approval, tracks how you respond through your account, and adjusts the dose without an appointment.
Yes. Request it from your account or the app; your physician approves or declines. If approved you pay for the additional medication at the pharmacy's cost and the new dose applies to your next shipment.
Yes. Add Melanotan II to a plan with another treatment and both go through one assessment and one physician review, shipping together on one schedule. Each keeps its own catalog price. The physician reviews the combination and can adjust it.
No. Compounded Melanotan II is not FDA-approved. It is prepared to your physician's prescription by a state-licensed, FDA-registered 503A pharmacy and every batch is independently tested before release.
Yes, when prescribed by a licensed physician and dispensed by a licensed pharmacy, which is how Pepti provides it in every state it serves. Research-use-only Melanotan II sold without a prescription is labeled not for human use and is a different product.
Melanotan II is a synthetic analog of alpha-MSH that stimulates melanocytes to produce melanin. At Pepti it is prescribed to support natural tan, uv protection support, skin pigmentation, cosmetic enhancement. Individual response varies, and your physician sets expectations at approval.
Melanotan II is a synthetic analog of alpha-MSH that stimulates melanocytes to produce melanin. Provides natural-looking pigmentation with minimal UV exposure. Compounded Melanotan II is not FDA-approved; it is prescribed off-label by a licensed physician after reviewing your assessment.
Melanotan II is prescribed for natural tan, uv protection support, skin pigmentation, cosmetic enhancement. It is commonly requested by adults seeking a deeper tan with less sun exposure; patients who understand this is not FDA-approved and carries real side effects. Whether it is appropriate for you is the reviewing physician's decision.
Melanotan II is studied for natural tan, uv protection support, skin pigmentation, cosmetic enhancement. Those are the goals it is prescribed to support at Pepti; results vary by person, dose, and consistency, and no outcome is guaranteed. Your physician tracks how you respond through your account.
Melanotan II went through early human dose-finding studies in the 1990s at the University of Arizona, demonstrating increased skin pigmentation, and separate small trials showed erectile responses (Wessells et al., J Urol 1998) — work that led to the FDA-approved derivative bremelanotide (Vyleesi). Melanotan II itself was never brought through full clinical development, so modern controlled safety and efficacy data are lacking. References are listed on this page.
Melanotan II is generally not prescribed with: active cancer or history of cancer (unless approved by oncologist); pregnancy or breastfeeding; severe kidney or liver disease; known allergy to the peptide or excipients; history of melanoma; atypical mole syndrome. The physician screens for these in your intake, and anything that rules Melanotan II out means it is not prescribed and is refunded.
At Pepti. Complete the free assessment, a physician licensed in your state reviews it within 4 hours, and if appropriate Melanotan II is compounded by a state-licensed, FDA-registered pharmacy and shipped free to your door for $249 per month, all-in. Not prescribed means refunded.
Injectable vial: 5 mL at 2 mg/mL, containing 10 mg Melanotan II. One vial is your monthly supply at the prescribed dose, and a fresh one ships about every 28 days.
Not currently. Melanotan II ships as a multi-dose vial with sterile syringes and prep pads. The pepti Pen is available for 10 other treatments.
$249 per month covers the compounded Melanotan II, the physician review, ongoing physician care including dose adjustments and refill review, unlimited messaging, and free tracked shipping. There is no membership, consult, visit, or refill fee; the only separate charges are optional at-home lab panels and a physician-approved dose increase billed at pharmacy cost.
Yes. Melanotan II is on Pepti's live catalog, which lists only treatments a partner pharmacy can compound and ship today. If a physician prescribes it, it ships; if it ever cannot be dispensed, the charge is refunded.
Melanotan II ships to 50 states, free and tracked, in insulated unbranded packaging. Eligibility is confirmed during the assessment from your shipping address.
$249 per month at Pepti. That includes the compounded Melanotan II, the physician review and ongoing care, free tracked shipping, and messaging, with no membership, consult, or visit fee. The price is the same in every state and every refill is the same price.
Pepti supplies Melanotan II as a monthly injectable vial with syringes and prep pads included, one vial per month at $249, prescribed by a licensed physician after a free online assessment and shipped free from a state-licensed, FDA-registered pharmacy in insulated packaging.
Yes. Pepti prescribes Melanotan II online in 50 states after a free assessment reviewed by a physician licensed in your state. It is compounded by an FDA-registered pharmacy and shipped free, $249 per month all-in. Not prescribed means refunded.
Yes. At Pepti the entire process is telehealth: a five-minute online assessment, physician review within 4 hours, then Melanotan II ships from the pharmacy. No clinic visit and no video appointment in most cases. $249 per month, all-in.
Yes, for the real thing. Melanotan II sold without a prescription is research-use-only product labeled not for human use, with no physician, no pharmacy, and no verified testing. Pepti's Melanotan II is physician-prescribed, pharmacy-compounded, batch-tested, and $249 per month including the physician and shipping.
Pepti does, in 50 states, with named board-certified physicians, a state-licensed FDA-registered compounding pharmacy, independent batch testing, and one published all-in price of $249 per month with no membership or consult fee. Refunded if the physician does not prescribe.
It is legal to be prescribed Melanotan II online by a licensed physician and have it dispensed by a licensed pharmacy, which is how Pepti provides it. Buying it as a research chemical without a prescription is a different product and is not for human use. Compounded Melanotan II is not FDA-approved.
$249 per month at Pepti, including the medication, the physician, and shipping. Refills are the same price and there is no membership fee.
Yes. Pepti has no clinics: the assessment, physician review, messaging, dose changes, and refills all happen online, and Melanotan II ships free from the pharmacy to your door in 50 states.
Start the free assessment at hellopepti.com, choose Melanotan II, and answer the health questions. A physician licensed in your state reviews it within 4 hours. If approved, Melanotan II ships within 1-3 business days and arrives in 1-3 more; if not, the $249 is refunded.
No. Melanotan II can be prescribed from the assessment alone at Pepti. Bloodwork is required only for GLP-1s and growth-hormone secretagogues.
Pepti ships Melanotan II to 50 states, free and tracked, refrigerated in insulated packaging, directly from the pharmacy. Delivery is 1-3 business days after the pharmacy compounds it.
Questions people ask
about Melanotan II (Injectable).
- Melanotan II: What It Is, Where to Get It Prescribed, and What It CostsMelanotan II — 5 mL multi-dose vial, Melanotan II 2 mg/mL (10 mg Melanotan II per vial). Specification, mechanism, dosing, formats, state availability and how to get it prescribed.
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- How to Inject Peptides Safely: Step by Step, Units, Sites and MistakesA practical subcutaneous injection walkthrough: reading your sig, converting millilitres to insulin-syringe units, the ten steps, site rotation, what to do about bubbles and missed doses.
Read more about Melanotan II (Injectable).
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