
Hexarelin (Injectable)
GH secretagogue
All-in monthly price
No membership fee · this is the full price · free shipping · avg 4-week supply
Add in-depth bloodwork
Optional — add a physician-reviewed at-home blood panel to your plan.
Your sex-hormone baseline plus the safety markers that matter on therapy — blood counts, liver and kidney function — from one painless upper-arm device. Matched to your sex (PSA for men; progesterone & FSH for women). No needle, no clinic, physician-reviewed.
This treatment requires licensed provider review and approval. Treatment is not guaranteed. If prescribed, medication is fulfilled by a licensed U.S. pharmacy where permitted by law. Compounded medications are not FDA-approved or FDA-cleared.

Reviewed by Dr. Gene, MD · Board-certified Family Medicine
Every Pepti prescription is reviewed by a licensed U.S. physician before it's dispensed — and only provided if clinically appropriate.
Hexarelin (Injectable)
Hexarelin prompts the body to release more of its own growth hormone. It is among the stronger peptides that do this, and it is also studied for protecting heart muscle. Used for recovery, sleep and body composition. Compounded; not FDA-approved.
About a 4-week supply supply at the standard prescribed dose — your physician confirms exact dosing.
A licensed US physician reviews your intake and prescribes when appropriate.
Compounded fresh at a US pharmacy and shipped cold-chain to your door.
Every order ships free — medication, physician care and refills, one all-in price.
Amounts shown are per unit. Compounded fresh at a US FDA-registered pharmacy.
Every batch independently tested
Every medication batch dispensed through Pepti is independently tested by a qualified third-party laboratory for applicable quality and safety standards before the pharmacy releases it. Batches are tested to the same standard used by 503B outsourcing facilities.
Confirms the finished preparation is free of viable microorganisms.
Screens for endotoxins that can cause fever or inflammatory reactions.
Verifies the labeled concentration of the active peptide is what is in the vial.
Checks the active peptide against impurities and degradation products.
Confirms the peptide in the vial is the correct molecule.
Confirms the solution sits within the range specified for injection.
Checks the finished vial for visible and sub-visible particles.
Confirms the vial seal holds so sterility is maintained through the beyond-use date.
- Lot 100526-HEX-0.4
Tested 2026-10-07 · Biolink Life Sciences Carolinas
Sterility
Sterile
Endotoxin
<2 EU/mL
Potency
99.6%
- Lot 092826-HEX-0.4
Tested 2026-09-30 · Biolink Life Sciences Carolinas
Sterility
Sterile
Endotoxin
<2 EU/mL
Potency
99.2%
- Lot 092126-HEX-0.4
Tested 2026-09-23 · Biolink Life Sciences Carolinas
Sterility
Sterile
Endotoxin
<2 EU/mL
Potency
99.2%
How Hexarelin is prescribed.
- Adults who want a stronger growth-hormone peptide than ipamorelin for recovery and lean muscle
- People over 35 who feel workouts take longer to bounce back from
- Patients whose physician wants to rotate secretagogues to keep the response strong
- Anyone interested in the heart-support research behind it
Your physician decides whether Hexarelin is appropriate for you after reviewing your intake and labs.
Inject 0.25 mL (25 units) subcutaneously Monday through Friday nights at bedtime.
- Licensed physician review of your intake, history, and labs
- Medication compounded to your prescription by a PCAB-accredited, FDA-registered pharmacy
- Every batch independently tested before release
- Sterile syringes and alcohol prep pads for injectables
- Tracked delivery to your door, refills on schedule
- Message your physician anytime; dose changes without an appointment
- Store refrigerated (36–46°F / 2–8°C) at all times, including before first use.
- One vial is your monthly supply. A fresh vial ships every 28 days on your refill schedule, so you're always well inside the beyond-use date on your label.
- Protect from light. Wipe the stopper with an alcohol pad before every draw.
- Dispose of syringes in the sharps container per the included instructions.
A typical course of Hexarelin.
Everything published
about Hexarelin.
How it is described to work, pathway by pathway. What the research shows and what it does not. Where it stands with the FDA, dated and sourced.
Read the referencepeer-reviewed, each verified on PubMed
mechanism, evidence, dosing, safety, FAQ
2026 · checked against fda.gov, not memory
How Hexarelin works, and what the research shows.
Hexarelin mimics the body's hunger hormone signal, which tells the pituitary gland to release a pulse of growth hormone.
It is a larger pulse than gentler peptides like ipamorelin produce.
It also binds a receptor in heart muscle, which is why it is studied for heart protection.
Human studies in the 1990s (Ghigo, Arvat and colleagues) showed strong growth-hormone release in adults, with the response easing somewhat when used continuously.
Heart-muscle effects are documented in animal studies and small human series.
References
- Ghigo E, Arvat E, Gianotti L et al.. Growth hormone-releasing activity of hexarelin, a new synthetic hexapeptide, after intravenous, subcutaneous, intranasal, and oral administration in man · J Clin Endocrinol Metab (1994) · PMID 8126144
- Rahim A, O'Neill PA, Shalet SM. Growth hormone status during long-term hexarelin therapy · J Clin Endocrinol Metab (1998) · PMID 9589671
- Rahim A, Shalet SM. Does desensitization to hexarelin occur? · Growth Horm IGF Res (1998) · PMID 10990150
- Ghigo E, Arvat E, Gianotti L et al.. Short-term administration of intranasal or oral Hexarelin, a synthetic hexapeptide, does not desensitize the growth hormone responsiveness in human aging · Eur J Endocrinol (1996) · PMID 8921821
- Klinger B, Silbergeld A, Deghenghi R et al.. Desensitization from long-term intranasal treatment with hexarelin does not interfere with the biological effects of this growth hormone-releasing peptide in short children · Eur J Endocrinol (1996) · PMID 8766941
- Laron Z, Frenkel J, Deghenghi R et al.. Intranasal administration of the GHRP hexarelin accelerates growth in short children · Clin Endocrinol (Oxf) (1995) · PMID 8548949
- Loche S, Cambiaso P, Carta D et al.. The growth hormone-releasing activity of hexarelin, a new synthetic hexapeptide, in short normal and obese children and in hypopituitary subjects · J Clin Endocrinol Metab (1995) · PMID 7852535
- Massoud AF, Hindmarsh PC, Matthews DR, Brook CG. The effect of repeated administration of hexarelin, a growth hormone releasing peptide, and growth hormone releasing hormone on growth hormone responsivity · Clin Endocrinol (Oxf) (1996) · PMID 8762732
- Maccario M, Veldhuis JD, Broglio F et al.. Impact of two or three daily subcutaneous injections of hexarelin, a synthetic growth hormone (GH) secretagogue, on 24-h GH, prolactin, adrenocorticotropin and cortisol secretion in humans · Eur J Endocrinol (2002) · PMID 11888836
- Arvat E, di Vito L, Maccagno B et al.. Effects of GHRP-2 and hexarelin, two synthetic GH-releasing peptides, on GH, prolactin, ACTH and cortisol levels in man. Comparison with the effects of GHRH, TRH and hCRH · Peptides (1997) · PMID 9285939
- Ghigo E, Arvat E, Ramunni J et al.. Adrenocorticotropin- and cortisol-releasing effect of hexarelin, a synthetic growth hormone-releasing peptide, in normal subjects and patients with Cushing's syndrome · J Clin Endocrinol Metab (1997) · PMID 9253314
- Arvat E, Ramunni J, Bellone J et al.. The GH, prolactin, ACTH and cortisol responses to Hexarelin, a synthetic hexapeptide, undergo different age-related variations · Eur J Endocrinol (1997) · PMID 9437229
- Arvat E, Gianotti L, Grottoli S et al.. Arginine and growth hormone-releasing hormone restore the blunted growth hormone-releasing activity of hexarelin in elderly subjects · J Clin Endocrinol Metab (1994) · PMID 7962341
- Arvat E, Maccario M, Di Vito L et al.. Endocrine activities of ghrelin, a natural growth hormone secretagogue (GHS), in humans: comparison and interactions with hexarelin, a nonnatural peptidyl GHS, and GH-releasing hormone · J Clin Endocrinol Metab (2001) · PMID 11238504
- Gasperi M, Aimaretti G, Scarcello G et al.. Low dose hexarelin and growth hormone (GH)-releasing hormone as a diagnostic tool for the diagnosis of GH deficiency in adults: comparison with insulin-induced hypoglycemia test · J Clin Endocrinol Metab (1999) · PMID 10443652
- Korbonits M, Kaltsas G, Perry LA et al.. Hexarelin as a test of pituitary reserve in patients with pituitary disease · Clin Endocrinol (Oxf) (1999) · PMID 10469018
- Maheshwari HG, Rahim A, Shalet SM, Baumann G. Selective lack of growth hormone (GH) response to the GH-releasing peptide hexarelin in patients with GH-releasing hormone receptor deficiency · J Clin Endocrinol Metab (1999) · PMID 10084578
- De Marinis L, Mancini A, Valle D et al.. Role of food intake in the modulation of hexarelin-induced growth hormone release in normal human subjects · Horm Metab Res (2000) · PMID 10824712
- Bisi G, Podio V, Valetto MR et al.. Acute cardiovascular and hormonal effects of GH and hexarelin, a synthetic GH-releasing peptide, in humans · J Endocrinol Invest (1999) · PMID 10342360
- Broglio F, Guarracino F, Benso A et al.. Effects of acute hexarelin administration on cardiac performance in patients with coronary artery disease during by-pass surgery · Eur J Pharmacol (2002) · PMID 12144941
- Imazio M, Bobbio M, Broglio F et al.. GH-independent cardiotropic activities of hexarelin in patients with severe left ventricular dysfunction due to dilated and ischemic cardiomyopathy · Eur J Heart Fail (2002) · PMID 11959048
- Locatelli V, Rossoni G, Schweiger F et al.. Growth hormone-independent cardioprotective effects of hexarelin in the rat · Endocrinology (1999) · PMID 10465272
- Tivesten A, Bollano E, Caidahl K et al.. The growth hormone secretagogue hexarelin improves cardiac function in rats after experimental myocardial infarction · Endocrinology (2000) · PMID 10614623
- Bodart V, Febbraio M, Demers A et al.. CD36 mediates the cardiovascular action of growth hormone-releasing peptides in the heart · Circ Res (2002) · PMID 11988484
- Xu X, Pang J, Yin H et al.. Hexarelin suppresses cardiac fibroblast proliferation and collagen synthesis in rat · Am J Physiol Heart Circ Physiol (2007) · PMID 17766487
- Xu X, Ding F, Pang J et al.. Chronic administration of hexarelin attenuates cardiac fibrosis in the spontaneously hypertensive rat · Am J Physiol Heart Circ Physiol (2012) · PMID 22842067
- McDonald H, Peart J, Kurniawan N et al.. Hexarelin treatment preserves myocardial function and reduces cardiac fibrosis in a mouse model of acute myocardial infarction · Physiol Rep (2018) · PMID 29756411
- Pang JJ, Xu RK, Xu XB et al.. Hexarelin protects rat cardiomyocytes from angiotensin II-induced apoptosis in vitro · Am J Physiol Heart Circ Physiol (2004) · PMID 14615277
- Filigheddu N, Fubini A, Baldanzi G et al.. Hexarelin protects H9c2 cardiomyocytes from doxorubicin-induced cell death · Endocrine (2001) · PMID 11322493
- Mao Y, Tokudome T, Kishimoto I. The cardiovascular action of hexarelin · J Geriatr Cardiol (2014) · PMID 25278975
- De Gennaro-Colonna V, Rossoni G, Cocchi D et al.. Endocrine, metabolic and cardioprotective effects of hexarelin in obese Zucker rats · J Endocrinol (2000) · PMID 10974647
- Pang J, Xu Q, Xu X et al.. Hexarelin suppresses high lipid diet and vitamin D3-induced atherosclerosis in the rat · Peptides (2010) · PMID 19931584
- Mosa R, Huang L, Wu Y et al.. Hexarelin, a Growth Hormone Secretagogue, Improves Lipid Metabolic Aberrations in Nonobese Insulin-Resistant Male MKR Mice · Endocrinology (2017) · PMID 28977588
- Demers A, Rodrigue-Way A, Tremblay A. Hexarelin Signaling to PPARgamma in Metabolic Diseases · PPAR Res (2008) · PMID 18288286
- Orkin RD, New DI, Norman D et al.. Rapid desensitisation of the GH secretagogue (ghrelin) receptor to hexarelin in vitro · J Endocrinol Invest (2003) · PMID 14669829
- Imbimbo BP, Mant T, Edwards M et al.. Growth hormone-releasing activity of hexarelin in humans. A dose-response study · Eur J Clin Pharmacol (1994) · PMID 7957536
- Semenistaya E, Zvereva I, Thomas A et al.. Determination of growth hormone releasing peptides metabolites in human urine after nasal administration of GHRP-1, GHRP-2, GHRP-6, Hexarelin, and Ipamorelin · Drug Test Anal (2015) · PMID 25869809
- Camiña JP, Carreira MC, El Messari S, Llorens-Cortes C, Smith RG, Casanueva FF. Desensitization and endocytosis mechanisms of ghrelin-activated growth hormone secretagogue receptor 1a · Endocrinology (2004) · PMID 14576181
- Delhanty PJ, van Kerkwijk A, Huisman M, van de Zande B et al.. Unsaturated fatty acids prevent desensitization of the human growth hormone secretagogue receptor by blocking its internalization · Am J Physiol Endocrinol Metab (2010) · PMID 20587751
Citations are provided for educational purposes. They do not constitute medical advice. Always discuss any peptide protocol with your prescribing physician.
Important safety information
+
Possible side effects
Do not use if you have
If you experience severe side effects, call 911 or go to your nearest emergency room.
vial — Hexarelin 12.5mg/5mL 2.5mg/mL (5mL)
Frequently asked
about Hexarelin (Injectable).
Hexarelin prompts the body to release more of its own growth hormone. It is among the stronger peptides that do this, and it is also studied for protecting heart muscle. Used for recovery, sleep and body composition. Compounded; not FDA-approved. Hexarelin is prescription-only at Pepti: a licensed physician reviews your assessment and, if appropriate, prescribes it to be compounded by a state-licensed, FDA-registered pharmacy.
Hexarelin is $209 per month at Pepti. That is all-in: medication, physician review and ongoing care, shipping, and messaging. No membership, consult, or visit fees, and the price is the same in every state.
Hexarelin is commonly prescribed for: Adults who want a stronger growth-hormone peptide than ipamorelin for recovery and lean muscle; People over 35 who feel workouts take longer to bounce back from; Patients whose physician wants to rotate secretagogues to keep the response strong; Anyone interested in the heart-support research behind it. Whether it is appropriate for you is decided by the reviewing physician from your history, medications, and labs where required.
Yes. Hexarelin is prescription-only. The free online assessment takes about five minutes, a physician licensed in your state reviews it within 4 hours, and if approved the prescription goes to the pharmacy. If not approved, the medication charge is refunded.
No. Hexarelin can be prescribed from the assessment alone. Bloodwork is required only for the GLP-1s and growth-hormone secretagogues, and the intake tells you if a medication on your order needs it.
Hexarelin is a subcutaneous injection into the abdomen or thigh with a small insulin syringe. Your kit ships with sterile syringes and alcohol prep pads, and the exact dose and schedule are printed on the pharmacy label. Dosing videos are in your account.
33 more questions about Pepti, answered.Show fewer
One vial is your monthly supply at the dose your physician prescribes. A fresh vial ships about every 28 days, and the date moves if your physician changes your dose. Store it as the pharmacy label directs, refrigerated.
Once per fill, $209 each time, when the next vial ships. It renews until you cancel, which you can do anytime from your account with no cancellation fee.
The compounded Hexarelin with sterile syringes and alcohol prep pads, free tracked shipping in an unbranded box with insulated packaging, the physician review, ongoing physician care and dose adjustments, and unlimited messaging.
Reported side effects of Hexarelin are usually mild: mild redness or swelling at injection site; temporary fatigue or headache; mild nausea (uncommon). The physician screens your history, medications, and allergies before prescribing, the medication-specific consent lists the known risks, and you can message your physician about anything you notice. Seek emergency care for severe symptoms.
Response varies by person, goal, and dose, and Hexarelin is prescribed for ongoing use rather than a short trial. Your physician sets expectations at approval, tracks how you respond through your account, and adjusts the dose without an appointment.
Any dose change is made by your physician from the chart, without an appointment. Message them through your account if you think your dose should change.
Yes. Add Hexarelin to a plan with another treatment and both go through one assessment and one physician review, shipping together on one schedule. Each keeps its own catalog price. The physician reviews the combination and can adjust it.
No. Compounded Hexarelin is not FDA-approved. It is prepared to your physician's prescription by a state-licensed, FDA-registered 503A pharmacy and every batch is independently tested before release.
Yes, when prescribed by a licensed physician and dispensed by a licensed pharmacy, which is how Pepti provides it in every state it serves. Research-use-only Hexarelin sold without a prescription is labeled not for human use and is a different product.
Hexarelin mimics the body's hunger hormone signal, which tells the pituitary gland to release a pulse of growth hormone. At Pepti it is prescribed to support strong growth-hormone release, studied for heart-muscle support, recovery and lean-muscle support, nightly injection, monday to friday. Individual response varies, and your physician sets expectations at approval.
Hexarelin mimics the body's hunger hormone signal, which tells the pituitary gland to release a pulse of growth hormone. It is a larger pulse than gentler peptides like ipamorelin produce. It also binds a receptor in heart muscle, which is why it is studied for heart protection. Compounded Hexarelin is not FDA-approved; it is prescribed off-label by a licensed physician after reviewing your assessment.
Hexarelin is prescribed for strong growth-hormone release, studied for heart-muscle support, recovery and lean-muscle support, nightly injection, monday to friday. It is commonly requested by adults who want a stronger growth-hormone peptide than ipamorelin for recovery and lean muscle; people over 35 who feel workouts take longer to bounce back from; patients whose physician wants to rotate secretagogues to keep the response strong; Anyone interested in the heart-support research behind it. Whether it is appropriate for you is the reviewing physician's decision.
Hexarelin is studied for strong growth-hormone release, studied for heart-muscle support, recovery and lean-muscle support, nightly injection, monday to friday. Those are the goals it is prescribed to support at Pepti; results vary by person, dose, and consistency, and no outcome is guaranteed. Your physician tracks how you respond through your account.
Human studies in the 1990s (Ghigo, Arvat and colleagues) showed strong growth-hormone release in adults, with the response easing somewhat when used continuously. Heart-muscle effects are documented in animal studies and small human series. References are listed on this page.
Hexarelin is generally not prescribed with: active cancer or history of cancer (unless approved by oncologist); pregnancy or breastfeeding; severe kidney or liver disease; known allergy to the peptide or excipients. The physician screens for these in your intake, and anything that rules Hexarelin out means it is not prescribed and is refunded.
At Pepti. Complete the free assessment, a physician licensed in your state reviews it within 4 hours, and if appropriate Hexarelin is compounded by a state-licensed, FDA-registered pharmacy and shipped free to your door for $209 per month, all-in. Not prescribed means refunded.
Injectable vial: 5 mL at 2.5 mg/mL, containing 12.5 mg Hexarelin. One vial is your monthly supply at the prescribed dose, and a fresh one ships about every 28 days.
Not currently. Hexarelin ships as a multi-dose vial with sterile syringes and prep pads. The pepti Pen is available for 10 other treatments.
$209 per month covers the compounded Hexarelin, the physician review, ongoing physician care including dose adjustments and refill review, unlimited messaging, and free tracked shipping. There is no membership, consult, visit, or refill fee; the only separate charges are optional at-home lab panels and a physician-approved dose increase billed at pharmacy cost.
Yes. Hexarelin is on Pepti's live catalog, which lists only treatments a partner pharmacy can compound and ship today. If a physician prescribes it, it ships; if it ever cannot be dispensed, the charge is refunded.
Hexarelin ships to 50 states, free and tracked, in insulated unbranded packaging. Eligibility is confirmed during the assessment from your shipping address.
$209 per month at Pepti. That includes the compounded Hexarelin, the physician review and ongoing care, free tracked shipping, and messaging, with no membership, consult, or visit fee. The price is the same in every state and every refill is the same price.
Pepti supplies Hexarelin as a monthly injectable vial with syringes and prep pads included, one vial per month at $209, prescribed by a licensed physician after a free online assessment and shipped free from a state-licensed, FDA-registered pharmacy in insulated packaging.
Yes. Pepti prescribes Hexarelin online in 50 states after a free assessment reviewed by a physician licensed in your state. It is compounded by an FDA-registered pharmacy and shipped free, $209 per month all-in. Not prescribed means refunded.
Yes. At Pepti the entire process is telehealth: a five-minute online assessment, physician review within 4 hours, then Hexarelin ships from the pharmacy. No clinic visit and no video appointment in most cases. $209 per month, all-in.
Yes, for the real thing. Hexarelin sold without a prescription is research-use-only product labeled not for human use, with no physician, no pharmacy, and no verified testing. Pepti's Hexarelin is physician-prescribed, pharmacy-compounded, batch-tested, and $209 per month including the physician and shipping.
Pepti does, in 50 states, with named board-certified physicians, a state-licensed FDA-registered compounding pharmacy, independent batch testing, and one published all-in price of $209 per month with no membership or consult fee. Refunded if the physician does not prescribe.
It is legal to be prescribed Hexarelin online by a licensed physician and have it dispensed by a licensed pharmacy, which is how Pepti provides it. Buying it as a research chemical without a prescription is a different product and is not for human use. Compounded Hexarelin is not FDA-approved.
$209 per month at Pepti, including the medication, the physician, and shipping. Refills are the same price and there is no membership fee.
Yes. Pepti has no clinics: the assessment, physician review, messaging, dose changes, and refills all happen online, and Hexarelin ships free from the pharmacy to your door in 50 states.
Start the free assessment at hellopepti.com, choose Hexarelin, and answer the health questions. A physician licensed in your state reviews it within 4 hours. If approved, Hexarelin ships within 1-3 business days and arrives in 1-3 more; if not, the $209 is refunded.
No. Hexarelin can be prescribed from the assessment alone at Pepti. Bloodwork is required only for GLP-1s and growth-hormone secretagogues.
Pepti ships Hexarelin to 50 states, free and tracked, refrigerated in insulated packaging, directly from the pharmacy. Delivery is 1-3 business days after the pharmacy compounds it.
Questions people ask
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Read more about Hexarelin (Injectable).
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