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Immune · Reference

Thymalin Dosage: How Pepti Prescribes It, in Units, mL and mg

This page explains the thymalin dosage Pepti prescribes, what the units on the syringe mean, a chart that converts units to millilitres and milligrams for this vial, how long a vial lasts, why thymalin is given in courses, what can change the directions, and the side effects to know about. It covers how Pepti's thymalin is typically prescribed, not dosing protocols from the internet. Nothing here is a reason to change your own dose.

Thymalin (Injectable)
Thymalin$209/mo

At Pepti, thymalin is prescribed as 0.25 mL, which is 25 units on a U-100 insulin syringe, injected under the skin once daily Monday through Friday. The vial is 5 mL at 1 mg/mL, so each dose carries 0.25 mg of thymalin and the vial holds 20 doses, about four weeks. Your physician sets your directions after reviewing your intake, and your exact dose and units are printed on the vial. There is no trial-derived thymalin dose: the human research is a Russian observational programme and two hospital reports, none of which supplies a dose to copy.

This page explains the thymalin dosage Pepti prescribes, what the units on the syringe mean, a chart that converts units to millilitres and milligrams for this vial, how long a vial lasts, why thymalin is given in courses, what can change the directions, and the side effects to know about. It covers how Pepti's thymalin is typically prescribed, not dosing protocols from the internet. Nothing here is a reason to change your own dose.

Thymalin Dosage

The short answer

Product Vial Typical directions Thymalin per dose Doses per vial Price
Thymalin 5 mL, 1 mg/mL (5 mg per vial) Inject 0.25 mL (25 units) subcutaneously once daily Monday through Friday 0.25 mg 20 $209/mo

The price is all-in, covering medication, physician review, refill management and shipping, with no separate membership fee. Pepti is cash-pay and does not bill insurance. These are the typical printed directions; your own directions are the ones on your vial. Thymalin is supplied as a vial only, in one strength.

Thymalin Dosage

What thymalin is, briefly

Thymalin is a polypeptide complex, a mixture of short peptides, extracted from the thymus gland of young cattle. That sets it apart from almost every other peptide Pepti supplies: BPC-157 or thymosin alpha-1 is one defined amino acid sequence, while thymalin is a standardized extract. The group that developed it describes two dipeptides, Lys-Glu (KE) and Glu-Trp (EW), as its active components. It was developed in Leningrad from 1973 onward by Vladimir Khavinson and Vyacheslav Morozov, and has been used clinically in Russia for decades. The full reference is what is thymalin.

Thymalin Dosage

Thymalin dosage in units, mL and mg

Pepti's directions are written in millilitres and units, because prescriptions are written in millilitres and insulin syringes are marked in units. On a U-100 insulin syringe, 1 unit is 0.01 mL, so 100 units is 1 mL and 25 units is 0.25 mL. A unit is a volume mark on the barrel, not a measure of how strong the medication is. Insulin syringe units explained goes through the standard in detail.

The milligram figure comes from the concentration on the label. Pepti's thymalin is 1 mg/mL, so:

What you read Value Where it comes from
Dose volume 0.25 mL Printed on the vial
On a U-100 insulin syringe 25 units 0.25 mL x 100 units per mL
Concentration 1 mg/mL Printed on the vial
Thymalin per dose 0.25 mg 1 mg/mL x 0.25 mL
Total in the vial 5 mg in 5 mL Printed on the vial
Doses per vial 20 5 mL divided by 0.25 mL

That arithmetic is a way to read a label, not a way to set a dose. A vial labelled 5 mg is not a 5 mg dose: it is twenty 0.25 mg doses. If your label and your syringe seem to disagree, do not dose; message your care team. How long does a peptide vial last explains every number on a vial label.

Thymalin Dosage

Thymalin conversion chart: units to mL to mg

Online thymalin charts quote doses in milligrams, micrograms and units interchangeably, and the numbers only line up if you know the concentration. The chart below is the conversion for a 1 mg/mL vial drawn with a U-100 insulin syringe. It is math only. It is not a menu of doses, and the only line that applies to you is the one that matches the number printed on your vial.

Syringe mark (U-100) Volume Thymalin from a 1 mg/mL vial
5 units 0.05 mL 0.05 mg
10 units 0.1 mL 0.1 mg
15 units 0.15 mL 0.15 mg
20 units 0.2 mL 0.2 mg
25 units (Pepti's typical directions) 0.25 mL 0.25 mg
50 units 0.5 mL 0.5 mg
100 units 1 mL 1 mg

The rule behind every row: units divided by 100 gives millilitres, and at 1 mg/mL the millilitres and the milligrams are the same number. A chart written for a different concentration will give different milligram figures for the same units, which is the main reason not to dose from a chart, including this one.

Thymalin Dosage

How long a thymalin vial lasts

At Pepti's typical directions, one 5 mg vial lasts four weeks:

Step Value
Dose 25 units, 0.25 mL, 0.25 mg
Doses per week 5 (Monday through Friday)
Doses per vial 20 (5 mL divided by 0.25 mL)
Thymalin used 20 x 0.25 mg = 5 mg, the whole vial
Time per vial 20 doses divided by 5 per week = 4 weeks

Four weeks is why refills run every 28 days, one vial per fill. Vials are multi-dose solutions shipped ready to use, refrigerated with ice packs, with sterile syringes and alcohol prep pads. Nothing is mixed at home. Keep the vial cold and out of light, do not freeze it, and follow the beyond-use date printed on the label, which runs from first puncture. How to store peptides covers storage.

If a vial runs short before the refill, message your care team rather than adjusting anything yourself. If you miss a dose, follow your directions and do not take two doses to make up for one.

Thymalin Dosage

When and how thymalin is taken

Directions say What it means in practice
0.25 mL (25 units) Draw to the 25 mark on a U-100 insulin syringe
Subcutaneously Into the fat layer, abdomen or thigh, rotating sites
Once daily One dose a day; the directions do not tie it to a time of day
Monday through Friday Five doses a week, weekends off
20 doses per vial About four weeks, then the next refill
  • Monday through Friday

    Five doses a week rather than seven is a pattern shared by a number of peptides Pepti supplies, and it reflects prescribing convention rather than a pharmacokinetic finding. Weekends off are part of the schedule, not missed doses.

  • Under the skin, anywhere suitable

    Subcutaneous means into the fat layer, not the muscle. Because the mechanisms described for thymalin are systemic, acting on circulating immune cells rather than a local tissue, there is no reason to inject near anything in particular. Technique is covered in how to inject peptides safely.

  • In courses

    The Russian programme behind thymalin treated older adults in courses repeated annually over the first two to three years, rather than as open-ended daily use, and that is the pattern most prescribers reference: a course, then a review against whatever was being watched. How long a course runs, and whether it is repeated, is set by your physician for your situation.

Thymalin Dosage

What the research used, and why that is not your dose

Thymalin's human literature does not supply a dose to copy, and it is worth knowing why before reading any chart online.

Study Who What it reports
Advances in Gerontology, 2002; Neuroendocrinology Letters, 2003 266 elderly and older people in St. Petersburg and Kiev, followed six to eight years Courses of thymalin, Epithalamin or both in the first two to three years; reported fewer respiratory infections and lower mortality than controls. No randomization, blinding or placebo described
Stem Cell Reviews and Reports, 2021 Hospital patients with COVID-19 in Russia A faster fall in IL-6, C-reactive protein and D-dimer alongside standard treatment. No randomization or blinding described
Advances in Gerontology, 2022 Middle-aged and elderly patients with severe COVID-19 Higher lymphocyte counts and lower clotting markers than standard care. Group sizes not given

There are no randomized controlled trials of thymalin. Almost all of the literature comes from one research group and its collaborators, much of it in Russian-language journals, and the published abstracts in the live research do not describe the dose in a way that maps onto a subcutaneous weekday schedule. The mechanism work, on blood stem cells and cytokine output, is in cells in a dish. That is why your directions come from a physician who has reviewed your intake, not from a study table. The evidence, claim by claim, is in thymalin benefits.

Thymalin Dosage

What changes the directions

Your physician sets your directions after reviewing your intake. Things that can lead to different directions, or a different product, include:

What can change How it shows up
Why it is being started Age-related immune decline is the use the research describes; how long a course runs follows from the goal
Thymalin or thymosin alpha-1 A different molecule, vial and directions; see below
Your medical history An autoimmune diagnosis, a diagnosed immunodeficiency or an active infection changes the conversation, usually with a specialist
Your other medications Immunosuppressants and biologics act on the same system; the intake asks for everything you take
How you respond Any rash, hives or swelling beyond the injection site goes to your care team

Thymalin vs thymosin alpha-1 dosing

These are the two immune peptides Pepti supplies, and they are not two doses of the same thing. Thymosin alpha-1 is a single 28-amino-acid synthetic sequence with international randomized trials; its 5 mL vial is 2 mg/mL, so the same 25-unit, Monday-through-Friday draw delivers 0.5 mg. Thymalin's 25 units deliver 0.25 mg of an extract. Same volume, different molecule, different milligrams. See thymosin alpha-1 dosage and thymosin alpha-1 vs thymalin.

Thymalin Dosage

Side effects

Thymalin has been given to people in Russia for decades, and the published clinical reports do not describe a characteristic toxicity. That is a long clinical tradition, not a modern safety trial.

What is reported or relevant How often What to do
Injection-site redness, mild soreness, bruising or itching The most commonly reported effect Rotate sites; mention it at follow-up
Rash, hives or swelling beyond the injection site Uncommon; a theoretical risk with an extract of animal origin Report it to your care team rather than waiting it out
Facial or throat swelling, widespread hives, difficulty breathing Rare Call 911, then tell your physician
Immunosuppressants, biologics or an autoimmune diagnosis Before treatment Raised at intake; reviewed by your physician
Pregnancy or breastfeeding Before treatment No safety data in the live research; tell your physician

There is no established interaction list, because the trials that would produce one have not been run. Stop and contact your physician for any reaction that is severe, spreading, or involves difficulty breathing.

Thymalin Dosage

Where thymalin stands with the FDA

Thymalin has never been nominated for the FDA's 503A bulk drug substances list and appears in no category of the interim list updated 14 May 2026. It was never in Category 2, was not part of the April 2026 removals, and was not on the July 2026 Pharmacy Compounding Advisory Committee agenda. "Thymulin acetate," a different thymic peptide, sits in Category 3. So the accurate description is never nominated, never flagged, never reviewed. Thymalin is not an FDA-approved drug, and compounded medications are not FDA approved.

Thymalin Dosage

Where to get thymalin prescribed

Thymalin cannot be bought legitimately without a prescription. As an extract rather than a single sequence, it depends even more than most peptides on the pharmacy that prepares it; vials sold "for research use only" have no pharmacy accountable for what is in them. See research peptides vs prescription peptides. The prescription route:

  1. Complete a free online intake covering your history, including any autoimmune condition, immune diagnosis or immune-acting medication, and what you want help with.
  2. A physician licensed in your state reviews it, usually within 24 hours.
  3. If it is appropriate, a PCAB-accredited, FDA-registered US 503A compounding pharmacy prepares it to that prescription. Lot test results are published at /quality/lab-results.
  4. It ships refrigerated with your directions printed on the vial.
  5. Your care team stays reachable for questions and side effects.

Step by step: how to get thymalin prescribed online. Bloodwork is not required for any Pepti treatment. If your physician wants labs for your care, they'll ask through your account.

References

What this is based on.

References

  1. Khavinson VKh, Morozov VG. [Geroprotective effect of thymalin and epithalamin] · Adv Gerontol (2002) · PMID 12577695
  2. Khavinson VKh. Peptides and Ageing · Neuro Endocrinol Lett (2002) · PMID 12374906
  3. Khavinson VK, Linkova NS, Kvetnoy IM, Polyakova VO, Drobintseva AO, Kvetnaia TV, Ivko OM. Thymalin: Activation of Differentiation of Human Hematopoietic Stem Cells · Bull Exp Biol Med (2020) · PMID 33237528
  4. Khavinson VK, Kuznik BI, Trofimova SV, Volchkov VA, Rukavishnikova SA, Titova ON, Akhmedov TA, Trofimov AV, Potemkin VV, Magen E. Results and Prospects of Using Activator of Hematopoietic Stem Cell Differentiation in Complex Therapy for Patients with COVID-19 · Stem Cell Rev Rep (2021) · PMID 33575961
  5. Kuznik BI, Shapovalov KG, Smolyakov YN, Lukyanov SA, Tereshkov PP, Kazantseva LS, Linkova NS. [Morphological compound and indicators of the blood clotting system in severe COVID-19 patients of middle aged and elderly during treatment of Tocilizumab and Thymalin] · Adv Gerontol (2022) · PMID 36169363
  6. Avolio F, Martinotti S, Khavinson VK, Esposito JE, Giambuzzi G, Marino A, Mironova E, Pulcini R, Robuffo I, Bologna G, Simeone P, Lanuti P, Guarnieri S, Trofimova S, Procopio AD, Toniato E. Peptides Regulating Proliferative Activity and Inflammatory Pathways in the Monocyte/Macrophage THP-1 Cell Line · Int J Mol Sci (2022) · PMID 35408963
  7. Linkova N, Khavinson V, Diatlova A, Petukhov M, Vladimirova E, Sukhareva M, Ilina A. The Influence of KE and EW Dipeptides in the Composition of the Thymalin Drug on Gene Expression and Protein Synthesis Involved in the Pathogenesis of COVID-19 · Int J Mol Sci (2023) · PMID 37686182

Citations are provided for educational purposes. They do not constitute medical advice. Always discuss any peptide protocol with your prescribing physician.

Common questions

Thymalin Dosage, answered.

At Pepti, the typical printed direction is 0.25 mL (25 units on a U-100 insulin syringe) subcutaneously once daily Monday through Friday. From the 1 mg/mL vial that is 0.25 mg per dose. Your exact directions are printed on your vial.

Next step

See what a physician recommends for you.

A licensed physician in your state reviews your intake and decides what is appropriate. A consultation does not guarantee a prescription.