Immune · Reference
Thymalin Dosage: How Pepti Prescribes It, in Units, mL and mg
This page explains the thymalin dosage Pepti prescribes, what the units on the syringe mean, a chart that converts units to millilitres and milligrams for this vial, how long a vial lasts, why thymalin is given in courses, what can change the directions, and the side effects to know about. It covers how Pepti's thymalin is typically prescribed, not dosing protocols from the internet. Nothing here is a reason to change your own dose.

Treatments mentioned
At Pepti, thymalin is prescribed as 0.25 mL, which is 25 units on a U-100 insulin syringe, injected under the skin once daily Monday through Friday. The vial is 5 mL at 1 mg/mL, so each dose carries 0.25 mg of thymalin and the vial holds 20 doses, about four weeks. Your physician sets your directions after reviewing your intake, and your exact dose and units are printed on the vial. There is no trial-derived thymalin dose: the human research is a Russian observational programme and two hospital reports, none of which supplies a dose to copy.
This page explains the thymalin dosage Pepti prescribes, what the units on the syringe mean, a chart that converts units to millilitres and milligrams for this vial, how long a vial lasts, why thymalin is given in courses, what can change the directions, and the side effects to know about. It covers how Pepti's thymalin is typically prescribed, not dosing protocols from the internet. Nothing here is a reason to change your own dose.
Thymalin Dosage
The short answer
| Product | Vial | Typical directions | Thymalin per dose | Doses per vial | Price |
|---|---|---|---|---|---|
| Thymalin | 5 mL, 1 mg/mL (5 mg per vial) | Inject 0.25 mL (25 units) subcutaneously once daily Monday through Friday | 0.25 mg | 20 | $209/mo |
The price is all-in, covering medication, physician review, refill management and shipping, with no separate membership fee. Pepti is cash-pay and does not bill insurance. These are the typical printed directions; your own directions are the ones on your vial. Thymalin is supplied as a vial only, in one strength.
Thymalin Dosage
What thymalin is, briefly
Thymalin is a polypeptide complex, a mixture of short peptides, extracted from the thymus gland of young cattle. That sets it apart from almost every other peptide Pepti supplies: BPC-157 or thymosin alpha-1 is one defined amino acid sequence, while thymalin is a standardized extract. The group that developed it describes two dipeptides, Lys-Glu (KE) and Glu-Trp (EW), as its active components. It was developed in Leningrad from 1973 onward by Vladimir Khavinson and Vyacheslav Morozov, and has been used clinically in Russia for decades. The full reference is what is thymalin.
Thymalin Dosage
Thymalin dosage in units, mL and mg
Pepti's directions are written in millilitres and units, because prescriptions are written in millilitres and insulin syringes are marked in units. On a U-100 insulin syringe, 1 unit is 0.01 mL, so 100 units is 1 mL and 25 units is 0.25 mL. A unit is a volume mark on the barrel, not a measure of how strong the medication is. Insulin syringe units explained goes through the standard in detail.
The milligram figure comes from the concentration on the label. Pepti's thymalin is 1 mg/mL, so:
| What you read | Value | Where it comes from |
|---|---|---|
| Dose volume | 0.25 mL | Printed on the vial |
| On a U-100 insulin syringe | 25 units | 0.25 mL x 100 units per mL |
| Concentration | 1 mg/mL | Printed on the vial |
| Thymalin per dose | 0.25 mg | 1 mg/mL x 0.25 mL |
| Total in the vial | 5 mg in 5 mL | Printed on the vial |
| Doses per vial | 20 | 5 mL divided by 0.25 mL |
That arithmetic is a way to read a label, not a way to set a dose. A vial labelled 5 mg is not a 5 mg dose: it is twenty 0.25 mg doses. If your label and your syringe seem to disagree, do not dose; message your care team. How long does a peptide vial last explains every number on a vial label.
Thymalin Dosage
Thymalin conversion chart: units to mL to mg
Online thymalin charts quote doses in milligrams, micrograms and units interchangeably, and the numbers only line up if you know the concentration. The chart below is the conversion for a 1 mg/mL vial drawn with a U-100 insulin syringe. It is math only. It is not a menu of doses, and the only line that applies to you is the one that matches the number printed on your vial.
| Syringe mark (U-100) | Volume | Thymalin from a 1 mg/mL vial |
|---|---|---|
| 5 units | 0.05 mL | 0.05 mg |
| 10 units | 0.1 mL | 0.1 mg |
| 15 units | 0.15 mL | 0.15 mg |
| 20 units | 0.2 mL | 0.2 mg |
| 25 units (Pepti's typical directions) | 0.25 mL | 0.25 mg |
| 50 units | 0.5 mL | 0.5 mg |
| 100 units | 1 mL | 1 mg |
The rule behind every row: units divided by 100 gives millilitres, and at 1 mg/mL the millilitres and the milligrams are the same number. A chart written for a different concentration will give different milligram figures for the same units, which is the main reason not to dose from a chart, including this one.
Thymalin Dosage
How long a thymalin vial lasts
At Pepti's typical directions, one 5 mg vial lasts four weeks:
| Step | Value |
|---|---|
| Dose | 25 units, 0.25 mL, 0.25 mg |
| Doses per week | 5 (Monday through Friday) |
| Doses per vial | 20 (5 mL divided by 0.25 mL) |
| Thymalin used | 20 x 0.25 mg = 5 mg, the whole vial |
| Time per vial | 20 doses divided by 5 per week = 4 weeks |
Four weeks is why refills run every 28 days, one vial per fill. Vials are multi-dose solutions shipped ready to use, refrigerated with ice packs, with sterile syringes and alcohol prep pads. Nothing is mixed at home. Keep the vial cold and out of light, do not freeze it, and follow the beyond-use date printed on the label, which runs from first puncture. How to store peptides covers storage.
If a vial runs short before the refill, message your care team rather than adjusting anything yourself. If you miss a dose, follow your directions and do not take two doses to make up for one.
Thymalin Dosage
When and how thymalin is taken
| Directions say | What it means in practice |
|---|---|
| 0.25 mL (25 units) | Draw to the 25 mark on a U-100 insulin syringe |
| Subcutaneously | Into the fat layer, abdomen or thigh, rotating sites |
| Once daily | One dose a day; the directions do not tie it to a time of day |
| Monday through Friday | Five doses a week, weekends off |
| 20 doses per vial | About four weeks, then the next refill |
Monday through Friday
Five doses a week rather than seven is a pattern shared by a number of peptides Pepti supplies, and it reflects prescribing convention rather than a pharmacokinetic finding. Weekends off are part of the schedule, not missed doses.
Under the skin, anywhere suitable
Subcutaneous means into the fat layer, not the muscle. Because the mechanisms described for thymalin are systemic, acting on circulating immune cells rather than a local tissue, there is no reason to inject near anything in particular. Technique is covered in how to inject peptides safely.
In courses
The Russian programme behind thymalin treated older adults in courses repeated annually over the first two to three years, rather than as open-ended daily use, and that is the pattern most prescribers reference: a course, then a review against whatever was being watched. How long a course runs, and whether it is repeated, is set by your physician for your situation.
Thymalin Dosage
What the research used, and why that is not your dose
Thymalin's human literature does not supply a dose to copy, and it is worth knowing why before reading any chart online.
| Study | Who | What it reports |
|---|---|---|
| Advances in Gerontology, 2002; Neuroendocrinology Letters, 2003 | 266 elderly and older people in St. Petersburg and Kiev, followed six to eight years | Courses of thymalin, Epithalamin or both in the first two to three years; reported fewer respiratory infections and lower mortality than controls. No randomization, blinding or placebo described |
| Stem Cell Reviews and Reports, 2021 | Hospital patients with COVID-19 in Russia | A faster fall in IL-6, C-reactive protein and D-dimer alongside standard treatment. No randomization or blinding described |
| Advances in Gerontology, 2022 | Middle-aged and elderly patients with severe COVID-19 | Higher lymphocyte counts and lower clotting markers than standard care. Group sizes not given |
There are no randomized controlled trials of thymalin. Almost all of the literature comes from one research group and its collaborators, much of it in Russian-language journals, and the published abstracts in the live research do not describe the dose in a way that maps onto a subcutaneous weekday schedule. The mechanism work, on blood stem cells and cytokine output, is in cells in a dish. That is why your directions come from a physician who has reviewed your intake, not from a study table. The evidence, claim by claim, is in thymalin benefits.
Thymalin Dosage
What changes the directions
Your physician sets your directions after reviewing your intake. Things that can lead to different directions, or a different product, include:
| What can change | How it shows up |
|---|---|
| Why it is being started | Age-related immune decline is the use the research describes; how long a course runs follows from the goal |
| Thymalin or thymosin alpha-1 | A different molecule, vial and directions; see below |
| Your medical history | An autoimmune diagnosis, a diagnosed immunodeficiency or an active infection changes the conversation, usually with a specialist |
| Your other medications | Immunosuppressants and biologics act on the same system; the intake asks for everything you take |
| How you respond | Any rash, hives or swelling beyond the injection site goes to your care team |
Thymalin vs thymosin alpha-1 dosing
These are the two immune peptides Pepti supplies, and they are not two doses of the same thing. Thymosin alpha-1 is a single 28-amino-acid synthetic sequence with international randomized trials; its 5 mL vial is 2 mg/mL, so the same 25-unit, Monday-through-Friday draw delivers 0.5 mg. Thymalin's 25 units deliver 0.25 mg of an extract. Same volume, different molecule, different milligrams. See thymosin alpha-1 dosage and thymosin alpha-1 vs thymalin.
Thymalin Dosage
Side effects
Thymalin has been given to people in Russia for decades, and the published clinical reports do not describe a characteristic toxicity. That is a long clinical tradition, not a modern safety trial.
| What is reported or relevant | How often | What to do |
|---|---|---|
| Injection-site redness, mild soreness, bruising or itching | The most commonly reported effect | Rotate sites; mention it at follow-up |
| Rash, hives or swelling beyond the injection site | Uncommon; a theoretical risk with an extract of animal origin | Report it to your care team rather than waiting it out |
| Facial or throat swelling, widespread hives, difficulty breathing | Rare | Call 911, then tell your physician |
| Immunosuppressants, biologics or an autoimmune diagnosis | Before treatment | Raised at intake; reviewed by your physician |
| Pregnancy or breastfeeding | Before treatment | No safety data in the live research; tell your physician |
There is no established interaction list, because the trials that would produce one have not been run. Stop and contact your physician for any reaction that is severe, spreading, or involves difficulty breathing.
Thymalin Dosage
Where thymalin stands with the FDA
Thymalin has never been nominated for the FDA's 503A bulk drug substances list and appears in no category of the interim list updated 14 May 2026. It was never in Category 2, was not part of the April 2026 removals, and was not on the July 2026 Pharmacy Compounding Advisory Committee agenda. "Thymulin acetate," a different thymic peptide, sits in Category 3. So the accurate description is never nominated, never flagged, never reviewed. Thymalin is not an FDA-approved drug, and compounded medications are not FDA approved.
Thymalin Dosage
Where to get thymalin prescribed
Thymalin cannot be bought legitimately without a prescription. As an extract rather than a single sequence, it depends even more than most peptides on the pharmacy that prepares it; vials sold "for research use only" have no pharmacy accountable for what is in them. See research peptides vs prescription peptides. The prescription route:
- Complete a free online intake covering your history, including any autoimmune condition, immune diagnosis or immune-acting medication, and what you want help with.
- A physician licensed in your state reviews it, usually within 24 hours.
- If it is appropriate, a PCAB-accredited, FDA-registered US 503A compounding pharmacy prepares it to that prescription. Lot test results are published at /quality/lab-results.
- It ships refrigerated with your directions printed on the vial.
- Your care team stays reachable for questions and side effects.
Step by step: how to get thymalin prescribed online. Bloodwork is not required for any Pepti treatment. If your physician wants labs for your care, they'll ask through your account.
References
What this is based on.
References
- Khavinson VKh, Morozov VG. [Geroprotective effect of thymalin and epithalamin] · Adv Gerontol (2002) · PMID 12577695
- Khavinson VKh. Peptides and Ageing · Neuro Endocrinol Lett (2002) · PMID 12374906
- Khavinson VK, Linkova NS, Kvetnoy IM, Polyakova VO, Drobintseva AO, Kvetnaia TV, Ivko OM. Thymalin: Activation of Differentiation of Human Hematopoietic Stem Cells · Bull Exp Biol Med (2020) · PMID 33237528
- Khavinson VK, Kuznik BI, Trofimova SV, Volchkov VA, Rukavishnikova SA, Titova ON, Akhmedov TA, Trofimov AV, Potemkin VV, Magen E. Results and Prospects of Using Activator of Hematopoietic Stem Cell Differentiation in Complex Therapy for Patients with COVID-19 · Stem Cell Rev Rep (2021) · PMID 33575961
- Kuznik BI, Shapovalov KG, Smolyakov YN, Lukyanov SA, Tereshkov PP, Kazantseva LS, Linkova NS. [Morphological compound and indicators of the blood clotting system in severe COVID-19 patients of middle aged and elderly during treatment of Tocilizumab and Thymalin] · Adv Gerontol (2022) · PMID 36169363
- Avolio F, Martinotti S, Khavinson VK, Esposito JE, Giambuzzi G, Marino A, Mironova E, Pulcini R, Robuffo I, Bologna G, Simeone P, Lanuti P, Guarnieri S, Trofimova S, Procopio AD, Toniato E. Peptides Regulating Proliferative Activity and Inflammatory Pathways in the Monocyte/Macrophage THP-1 Cell Line · Int J Mol Sci (2022) · PMID 35408963
- Linkova N, Khavinson V, Diatlova A, Petukhov M, Vladimirova E, Sukhareva M, Ilina A. The Influence of KE and EW Dipeptides in the Composition of the Thymalin Drug on Gene Expression and Protein Synthesis Involved in the Pathogenesis of COVID-19 · Int J Mol Sci (2023) · PMID 37686182
Citations are provided for educational purposes. They do not constitute medical advice. Always discuss any peptide protocol with your prescribing physician.
Common questions
Thymalin Dosage, answered.
At Pepti, the typical printed direction is 0.25 mL (25 units on a U-100 insulin syringe) subcutaneously once daily Monday through Friday. From the 1 mg/mL vial that is 0.25 mg per dose. Your exact directions are printed on your vial.
Follow the units printed on your vial. Pepti's typical direction is 25 units, which is 0.25 mL and 0.25 mg from the 1 mg/mL vial.
From a 1 mg/mL vial, 25 units is 0.25 mL, which holds 0.25 mg. From a vial at a different concentration it would be a different amount, which is why the label on the vial in hand is the one that counts.
Four weeks at the typical directions: 20 doses of 0.25 mL, five a week. That is why refills run every 28 days, one vial per fill.
Pepti's typical direction is once daily Monday through Friday, with weekends off as part of the schedule.
The Russian programme gave courses repeated annually rather than open-ended daily use, and prescribers generally follow that pattern. The length of your course is set by your physician based on why it was started.
The live research does not report one that maps onto a subcutaneous schedule, and none of the studies was a randomized trial. That is why there is no study dose to copy.
No. They are different molecules. Pepti's thymosin alpha-1 vial is 2 mg/mL, so the same 25-unit draw delivers 0.5 mg; thymalin's delivers 0.25 mg of an extract.
No. Never change your own dose. If you think your directions should change, message your care team.
Mostly injection-site redness, soreness, bruising or itching. As an animal-derived extract it carries a theoretical allergy risk, so report any rash or swelling beyond the site, and call 911 for throat swelling or difficulty breathing.
At Pepti, thymalin is $209 a month, all-in, covering medication, physician review, refill management and shipping.
No. Bloodwork is not required for any Pepti treatment. If your physician wants labs for your care, they'll ask through your account. The free assessment goes to a physician licensed in your state. A consultation does not guarantee a prescription.
Next step
See what a physician recommends for you.
A licensed physician in your state reviews your intake and decides what is appropriate. A consultation does not guarantee a prescription.
