
DSIP (Delta Sleep Inducing Peptide) (Injectable)
Deep restorative sleep
Choose your strength
Every strength is a 4-week supply. A higher strength means more medication per dose on the same monthly cycle. Your provider confirms the dose at review.
All-in monthly price · 5mg
No membership fee · this is the full price · free shipping · avg 4-week supply
Add in-depth bloodwork
Optional — add a physician-reviewed at-home blood panel to your plan.
Your sex-hormone baseline plus the safety markers that matter on therapy — blood counts, liver and kidney function — from one painless upper-arm device. Matched to your sex (PSA for men; progesterone & FSH for women). No needle, no clinic, physician-reviewed.
This treatment requires licensed provider review and approval. Treatment is not guaranteed. If prescribed, medication is fulfilled by a licensed U.S. pharmacy where permitted by law. Compounded medications are not FDA-approved or FDA-cleared.

Reviewed by Dr. Gene, MD · Board-certified Family Medicine
Every Pepti prescription is reviewed by a licensed U.S. physician before it's dispensed — and only provided if clinically appropriate.
DSIP (Delta Sleep Inducing Peptide) (Injectable)
A neuropeptide that promotes delta wave sleep patterns for deeper, more restorative rest.
About a 4-week supply supply at the standard prescribed dose — your physician confirms exact dosing.
A licensed US physician reviews your intake and prescribes when appropriate.
Compounded fresh at a US pharmacy and shipped cold-chain to your door.
Every order ships free — medication, physician care and refills, one all-in price.
Amounts shown are per unit. Compounded fresh at a US FDA-registered pharmacy.
Every batch independently tested
Every medication batch dispensed through Pepti is independently tested by a qualified third-party laboratory for applicable quality and safety standards before the pharmacy releases it. Batches are tested to the same standard used by 503B outsourcing facilities.
Confirms the finished preparation is free of viable microorganisms.
Screens for endotoxins that can cause fever or inflammatory reactions.
Verifies the labeled concentration of the active peptide is what is in the vial.
Checks the active peptide against impurities and degradation products.
Confirms the peptide in the vial is the correct molecule.
Confirms the solution sits within the range specified for injection.
Checks the finished vial for visible and sub-visible particles.
Confirms the vial seal holds so sterility is maintained through the beyond-use date.
- Lot 100526-DSI-1
Tested 2026-10-07 · Biolink Life Sciences Carolinas
Sterility
Sterile
Endotoxin
<2 EU/mL
Potency
100.7%
- Lot 092826-DSI-1
Tested 2026-09-30 · Biolink Life Sciences Carolinas
Sterility
Sterile
Endotoxin
<2 EU/mL
Potency
100.2%
- Lot 092126-DSI-1
Tested 2026-09-23 · Biolink Life Sciences Carolinas
Sterility
Sterile
Endotoxin
<2 EU/mL
Potency
100.1%
How DSIP is prescribed.
- Adults with trouble falling or staying asleep
- Patients who want a sleep peptide rather than a sedative
Your physician decides whether DSIP is appropriate for you after reviewing your intake and labs.
Inject 0.25 mL (25 units) subcutaneously Monday through Friday nights at bedtime.
- Licensed physician review of your intake, history, and labs
- Medication compounded to your prescription by a PCAB-accredited, FDA-registered pharmacy
- Every batch independently tested before release
- Sterile syringes and alcohol prep pads for injectables
- Tracked delivery to your door, refills on schedule
- Message your physician anytime; dose changes without an appointment
- Store refrigerated (36–46°F / 2–8°C) at all times, including before first use.
- One vial is your monthly supply. A fresh vial ships every 28 days on your refill schedule, so you're always well inside the beyond-use date on your label.
- Protect from light. Wipe the stopper with an alcohol pad before every draw.
- Dispose of syringes in the sharps container per the included instructions.
A typical course of DSIP.
Everything published
about DSIP (Delta Sleep Inducing Peptide).
How it is described to work, pathway by pathway. What the research shows and what it does not. Where it stands with the FDA, dated and sourced.
Read the referencepeer-reviewed, each verified on PubMed
mechanism, evidence, dosing, safety, FAQ
2026 · checked against fda.gov, not memory
How DSIP works, and what the research shows.
Delta Sleep Inducing Peptide (DSIP) is a neuropeptide that promotes delta wave (deep) sleep stages.
It normalizes disrupted sleep architecture and is non-addictive.
Delta sleep-inducing peptide was isolated in 1977 (Schoenenberger and Monnier) from work on sleep induction, and small human studies in the 1980s reported improved sleep efficiency in some insomnia patients while others showed no effect.
The human evidence base is small, dated, and mixed — DSIP remains an investigational sleep peptide prescribed at physician discretion.
References
- Schneider-Helmert D. DSIP in sleep disturbances · Eur Neurol (1986) · PMID 3758119
- Graf MV, Kastin AJ. Delta-sleep-inducing peptide (DSIP): a review · Neurosci Biobehav Rev (1984) · PMID 6145137
- Schoenenberger GA, Monnier M. Characterization of a delta-electroencephalogram (-sleep)-inducing peptide · Proc Natl Acad Sci U S A (1977) · PMID 265572
- Schneider-Helmert D, Graf M, Schoenenberger GA. Synthetic delta-sleep-inducing peptide improves sleep in insomniacs · Lancet (1981) · PMID 6112579
- Schneider-Helmert D, Schoenenberger GA. The influence of synthetic DSIP (delta-sleep-inducing-peptide) on disturbed human sleep · Experientia (1981) · PMID 7028502
- Schneider-Helmert D. Effects of delta-sleep-inducing peptide on 24-hour sleep-wake behaviour in severe chronic insomnia · Eur Neurol (1987) · PMID 3622582
- Monti JM, Debellis J, Alterwain P, Pellejero T, Monti D. Study of delta sleep-inducing peptide efficacy in improving sleep on short-term administration to chronic insomniacs · Int J Clin Pharmacol Res (1987) · PMID 3583493
- Bes F, Hofman W, Schuur J, Van Boxtel C. Effects of delta sleep-inducing peptide on sleep of chronic insomniac patients. A double-blind study · Neuropsychobiology (1992) · PMID 1299794
- Dick P, Costa C, Fayolle K, Grandjean ME, Khoshbeen A, Tissot R. DSIP in the treatment of withdrawal syndromes from alcohol and opiates · Eur Neurol (1984) · PMID 6548969
- Backmund M, Meyer K, Rothenhaeusler HB, Soyka M. Opioid detoxification with delta sleep-inducing peptide: results of an open clinical trial · J Clin Psychopharmacol (1998) · PMID 9617990
- Larbig W, Gerber WD, Kluck M, Schoenenberger GA. Therapeutic effects of delta-sleep-inducing peptide (DSIP) in patients with chronic, pronounced pain episodes. A clinical pilot study · Eur Neurol (1984) · PMID 6548970
- Scherschlicht R, Aeppli L, Polc P, Haefely W. Some pharmacological effects of delta-sleep-inducing peptide (DSIP) · Eur Neurol (1984) · PMID 6548967
- Graf MV, Kastin AJ, Coy DH, Fischman AJ. Delta-sleep-inducing peptide reduces CRF-induced corticosterone release · Neuroendocrinology (1985) · PMID 2995861
- Sudakov KV, Umriukhin PE, Koplik EV, Anokhin KV. Delta-sleep inducing peptide (DSIP) and ACTH (4-10) analogue influence fos-induction in the limbic structures of the rat brain under emotional stress · Stress (2001) · PMID 22432135
- Stanojlović OP, Zivanović DP, Mirković SD, Mikhaleva II. Antiepileptic activity of delta sleep-inducing peptide and its analogue in metaphit-provoked seizures in rats · Seizure (2005) · PMID 15911358
- Popovich IG, Voitenkov BO, Anisimov VN, et al.. Effect of delta-sleep inducing peptide-containing preparation Deltaran on biomarkers of aging, life span and spontaneous tumor incidence in female SHR mice · Mech Ageing Dev (2003) · PMID 12782416
- Graf MV, Kastin AJ. Delta-sleep-inducing peptide (DSIP): an update · Peptides (1986) · PMID 3550726
- Kovalzon VM, Strekalova TV. Delta sleep-inducing peptide (DSIP): a still unresolved riddle · J Neurochem (2006) · PMID 16539679
- Chinoy ED, Cuellar JA, Huwa KE, Jameson JT et al.. Performance of seven consumer sleep-tracking devices compared with polysomnography · Sleep (2021) · PMID 33378539
Citations are provided for educational purposes. They do not constitute medical advice. Always discuss any peptide protocol with your prescribing physician.
Important safety information
+
Possible side effects
Do not use if you have
If you experience severe side effects, call 911 or go to your nearest emergency room.
5 mL multi-dose vial, DSIP 1 mg/mL (5 mg DSIP per vial)
Frequently asked
about DSIP (Delta Sleep Inducing Peptide) (Injectable).
A neuropeptide that promotes delta wave sleep patterns for deeper, more restorative rest. DSIP (Delta Sleep Inducing Peptide) is prescription-only at Pepti: a licensed physician reviews your assessment and, if appropriate, prescribes it to be compounded by a state-licensed, FDA-registered pharmacy.
DSIP (Delta Sleep Inducing Peptide) is $249 per month at Pepti. That is all-in: medication, physician review and ongoing care, shipping, and messaging. No membership, consult, or visit fees, and the price is the same in every state.
DSIP (Delta Sleep Inducing Peptide) is commonly prescribed for: Adults with trouble falling or staying asleep; Patients who want a sleep peptide rather than a sedative. Whether it is appropriate for you is decided by the reviewing physician from your history, medications, and labs where required.
Yes. DSIP (Delta Sleep Inducing Peptide) is prescription-only. The free online assessment takes about five minutes, a physician licensed in your state reviews it within 4 hours, and if approved the prescription goes to the pharmacy. If not approved, the medication charge is refunded.
No. DSIP (Delta Sleep Inducing Peptide) can be prescribed from the assessment alone. Bloodwork is required only for the GLP-1s and growth-hormone secretagogues, and the intake tells you if a medication on your order needs it.
DSIP (Delta Sleep Inducing Peptide) is a subcutaneous injection into the abdomen or thigh with a small insulin syringe. Your kit ships with sterile syringes and alcohol prep pads, and the exact dose and schedule are printed on the pharmacy label. Dosing videos are in your account.
33 more questions about Pepti, answered.Show fewer
One vial is your monthly supply at the dose your physician prescribes. A fresh vial ships about every 28 days, and the date moves if your physician changes your dose. Store it as the pharmacy label directs, refrigerated.
Once per fill, $249 each time, when the next vial ships. It renews until you cancel, which you can do anytime from your account with no cancellation fee.
The compounded DSIP (Delta Sleep Inducing Peptide) with sterile syringes and alcohol prep pads, free tracked shipping in an unbranded box with insulated packaging, the physician review, ongoing physician care and dose adjustments, and unlimited messaging.
Reported side effects of DSIP (Delta Sleep Inducing Peptide) are usually mild: vivid dreams (common); slight grogginess on waking (uncommon). The physician screens your history, medications, and allergies before prescribing, the medication-specific consent lists the known risks, and you can message your physician about anything you notice. Seek emergency care for severe symptoms.
Response varies by person, goal, and dose, and DSIP (Delta Sleep Inducing Peptide) is prescribed for ongoing use rather than a short trial. Your physician sets expectations at approval, tracks how you respond through your account, and adjusts the dose without an appointment.
Yes. Request it from your account or the app; your physician approves or declines. If approved you pay for the additional medication at the pharmacy's cost and the new dose applies to your next shipment.
Yes. Add DSIP (Delta Sleep Inducing Peptide) to a plan with another treatment and both go through one assessment and one physician review, shipping together on one schedule. Each keeps its own catalog price. The physician reviews the combination and can adjust it.
No. Compounded DSIP (Delta Sleep Inducing Peptide) is not FDA-approved. It is prepared to your physician's prescription by a state-licensed, FDA-registered 503A pharmacy and every batch is independently tested before release.
Yes, when prescribed by a licensed physician and dispensed by a licensed pharmacy, which is how Pepti provides it in every state it serves. Research-use-only DSIP (Delta Sleep Inducing Peptide) sold without a prescription is labeled not for human use and is a different product.
Delta Sleep Inducing Peptide (DSIP) is a neuropeptide that promotes delta wave (deep) sleep stages. At Pepti it is prescribed to support sleep quality, sleep onset, stress reduction, recovery during sleep. Individual response varies, and your physician sets expectations at approval.
Delta Sleep Inducing Peptide (DSIP) is a neuropeptide that promotes delta wave (deep) sleep stages. It normalizes disrupted sleep architecture and is non-addictive. Compounded DSIP (Delta Sleep Inducing Peptide) is not FDA-approved; it is prescribed off-label by a licensed physician after reviewing your assessment.
DSIP (Delta Sleep Inducing Peptide) is prescribed for sleep quality, sleep onset, stress reduction, recovery during sleep. It is commonly requested by adults with trouble falling or staying asleep; patients who want a sleep peptide rather than a sedative. Whether it is appropriate for you is the reviewing physician's decision.
DSIP (Delta Sleep Inducing Peptide) is studied for sleep quality, sleep onset, stress reduction, recovery during sleep. Those are the goals it is prescribed to support at Pepti; results vary by person, dose, and consistency, and no outcome is guaranteed. Your physician tracks how you respond through your account.
Delta sleep-inducing peptide was isolated in 1977 (Schoenenberger and Monnier) from work on sleep induction, and small human studies in the 1980s reported improved sleep efficiency in some insomnia patients while others showed no effect. The human evidence base is small, dated, and mixed — DSIP remains an investigational sleep peptide prescribed at physician discretion. References are listed on this page.
DSIP (Delta Sleep Inducing Peptide) is generally not prescribed with: active cancer or history of cancer (unless approved by oncologist); pregnancy or breastfeeding; severe kidney or liver disease; known allergy to the peptide or excipients. The physician screens for these in your intake, and anything that rules DSIP (Delta Sleep Inducing Peptide) out means it is not prescribed and is refunded.
At Pepti. Complete the free assessment, a physician licensed in your state reviews it within 4 hours, and if appropriate DSIP (Delta Sleep Inducing Peptide) is compounded by a state-licensed, FDA-registered pharmacy and shipped free to your door for $249 per month, all-in. Not prescribed means refunded.
Injectable vial: 5 mL at 2 mg/mL, containing 10 mg DSIP. Injectable vial: 5 mL at 1 mg/mL, containing 5 mg DSIP. One vial is your monthly supply at the prescribed dose, and a fresh one ships about every 28 days.
Not currently. DSIP (Delta Sleep Inducing Peptide) ships as a multi-dose vial with sterile syringes and prep pads. The pepti Pen is available for 10 other treatments.
$249 per month covers the compounded DSIP (Delta Sleep Inducing Peptide), the physician review, ongoing physician care including dose adjustments and refill review, unlimited messaging, and free tracked shipping. There is no membership, consult, visit, or refill fee; the only separate charges are optional at-home lab panels and a physician-approved dose increase billed at pharmacy cost.
Yes. DSIP (Delta Sleep Inducing Peptide) is on Pepti's live catalog, which lists only treatments a partner pharmacy can compound and ship today. If a physician prescribes it, it ships; if it ever cannot be dispensed, the charge is refunded.
DSIP (Delta Sleep Inducing Peptide) ships to 50 states, free and tracked, in insulated unbranded packaging. Eligibility is confirmed during the assessment from your shipping address.
$249 per month at Pepti. That includes the compounded DSIP (Delta Sleep Inducing Peptide), the physician review and ongoing care, free tracked shipping, and messaging, with no membership, consult, or visit fee. The price is the same in every state and every refill is the same price.
Pepti supplies DSIP (Delta Sleep Inducing Peptide) as a monthly injectable vial with syringes and prep pads included, one vial per month at $249, prescribed by a licensed physician after a free online assessment and shipped free from a state-licensed, FDA-registered pharmacy in insulated packaging.
Yes. Pepti prescribes DSIP (Delta Sleep Inducing Peptide) online in 50 states after a free assessment reviewed by a physician licensed in your state. It is compounded by an FDA-registered pharmacy and shipped free, $249 per month all-in. Not prescribed means refunded.
Yes. At Pepti the entire process is telehealth: a five-minute online assessment, physician review within 4 hours, then DSIP (Delta Sleep Inducing Peptide) ships from the pharmacy. No clinic visit and no video appointment in most cases. $249 per month, all-in.
Yes, for the real thing. DSIP (Delta Sleep Inducing Peptide) sold without a prescription is research-use-only product labeled not for human use, with no physician, no pharmacy, and no verified testing. Pepti's DSIP (Delta Sleep Inducing Peptide) is physician-prescribed, pharmacy-compounded, batch-tested, and $249 per month including the physician and shipping.
Pepti does, in 50 states, with named board-certified physicians, a state-licensed FDA-registered compounding pharmacy, independent batch testing, and one published all-in price of $249 per month with no membership or consult fee. Refunded if the physician does not prescribe.
It is legal to be prescribed DSIP (Delta Sleep Inducing Peptide) online by a licensed physician and have it dispensed by a licensed pharmacy, which is how Pepti provides it. Buying it as a research chemical without a prescription is a different product and is not for human use. Compounded DSIP (Delta Sleep Inducing Peptide) is not FDA-approved.
$249 per month at Pepti, including the medication, the physician, and shipping. Refills are the same price and there is no membership fee.
Yes. Pepti has no clinics: the assessment, physician review, messaging, dose changes, and refills all happen online, and DSIP (Delta Sleep Inducing Peptide) ships free from the pharmacy to your door in 50 states.
Start the free assessment at hellopepti.com, choose DSIP (Delta Sleep Inducing Peptide), and answer the health questions. A physician licensed in your state reviews it within 4 hours. If approved, DSIP (Delta Sleep Inducing Peptide) ships within 1-3 business days and arrives in 1-3 more; if not, the $249 is refunded.
No. DSIP (Delta Sleep Inducing Peptide) can be prescribed from the assessment alone at Pepti. Bloodwork is required only for GLP-1s and growth-hormone secretagogues.
Pepti ships DSIP (Delta Sleep Inducing Peptide) to 50 states, free and tracked, refrigerated in insulated packaging, directly from the pharmacy. Delivery is 1-3 business days after the pharmacy compounds it.
Questions people ask
about DSIP (Delta Sleep Inducing Peptide) (Injectable).
- DSIP (Delta Sleep Inducing Peptide): What It Is, Where to Get It Prescribed, and What It CostsDSIP (Delta Sleep Inducing Peptide) — 5 mL multi-dose vial, DSIP 1 mg/mL (5 mg DSIP per vial). Specification, mechanism, dosing, formats, state availability and how to get it prescribed.
- Peptides for Sleep: What Is Actually Prescribed and What It CostsThe peptides used for sleep quality, what DSIP and the growth-hormone-axis peptides each do, how they are dosed, what they cost, and when sleep needs a diagnosis instead.
- How Much Do Peptides Cost? Real Monthly Prices and What Drives ThemWhat prescription peptides actually cost per month, why single molecules price differently from four-peptide blends, which costs providers hide behind a low headline, and how to compare.
- Do You Need a Doctor to Get Peptides? Yes, and Here Is Exactly WhyPeptides used clinically are prescription medications. Why a prescriber is legally required, what your own doctor will likely say, and what a real review looks like online.
- How to Inject Peptides Safely: Step by Step, Units, Sites and MistakesA practical subcutaneous injection walkthrough: reading your sig, converting millilitres to insulin-syringe units, the ten steps, site rotation, what to do about bubbles and missed doses.
Read more about DSIP (Delta Sleep Inducing Peptide) (Injectable).
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