Not sure where to start? Get matched →
How it worksBlood TestingDaily PackPepti OnePepti PenCreator PartnershipsAccountGet started →
Weight Loss

Tirzepatide (Injectable)

Next-gen weight loss

Tirzepatide (Injectable)

— Your starting dose

New to this medication? Your provider starts you low and steps you up over time.

— All-in monthly price

$139

No membership fee · this is the full price · free shipping · avg 4-week supply

Medication, provider care, labs & dose adjustments — all in one price.
~28-day supply. Your provider sets your exact dose, so yours may vary — your refill arrives as you finish the last one.
Start assessment

— Add in-depth bloodwork

Optional — add a physician-reviewed at-home blood panel to your plan.

At-home kit (1 device)+$149

Your sex-hormone baseline plus the safety markers that matter on therapy — blood counts, liver and kidney function — from one painless upper-arm device. Matched to your sex (PSA for men; progesterone & FSH for women). No needle, no clinic, physician-reviewed.

This treatment requires licensed provider review and approval. Treatment is not guaranteed. If prescribed, medication is fulfilled by a licensed U.S. pharmacy where permitted by law. Compounded medications are not FDA-approved or FDA-cleared.

Money-back guarantee
Free AI care assistant
HSA/FSA accepted
Cancel anytime
Free shipping
Dr. Gene Lee
Physician
Reviewed

Reviewed by Dr. Gene Lee, MD · Board-certified Family Medicine

Every Pepti prescription is reviewed by a licensed U.S. physician before it's dispensed — and only provided if clinically appropriate.

— About

Tirzepatide (Injectable)

Dual GIP and GLP-1 receptor agonist offering enhanced weight management benefits.

— Benefits

Dual GIP/GLP-1 action
Superior weight loss
Metabolic health
Appetite reduction

Supply per fill

28-day

About a 4-week supply supply at the standard prescribed dose — your physician confirms exact dosing.

Physician review

24 hrs

A licensed US physician reviews your intake and prescribes when appropriate.

FDA-registered pharmacy

503A

Compounded fresh at a US pharmacy and shipped cold-chain to your door.

Shipping, always

Free

Every order ships free — medication, physician care and refills, one all-in price.

— Formulation

Injectable vial2 mL
Tirzepatidecompounded to your dose
Pyridoxine (B6)included
Strength is compounded to the exact dose your physician prescribes and stepped up over time; paired with B6 to ease nausea.
Amounts shown are per unit. Compounded fresh at a US FDA-registered pharmacy.

— Quality

Every batch independently tested

Every medication batch dispensed through Pepti is independently tested by a qualified third-party laboratory for applicable quality and safety standards before the pharmacy releases it. Batches are tested to the same standard used by 503B outsourcing facilities.

Sterility

USP <71>

Confirms the finished preparation is free of viable microorganisms.

Bacterial endotoxins

USP <85>

Screens for endotoxins that can cause fever or inflammatory reactions.

Potency

Assay

Verifies the labeled concentration of the active peptide is what is in the vial.

Purity

HPLC

Checks the active peptide against impurities and degradation products.

Identity

Mass spectrometry

Confirms the peptide in the vial is the correct molecule.

pH

USP <791>

Confirms the solution sits within the range specified for injection.

Particulate matter

USP <788>

Checks the finished vial for visible and sub-visible particles.

Container closure integrity

USP <1207>

Confirms the vial seal holds so sterility is maintained through the beyond-use date.

Compounded by licensed U.S. pharmacies. Prescribed by licensed medical providers. Shipped directly to patients.Documentation available upon request →View lab results by lot →

— Your protocol

How Tirzepatide is prescribed.

— Who it's for

  • Adults with a BMI in the range their physician considers appropriate for dual GIP/GLP-1 therapy
  • Patients who did not reach their goal on semaglutide
  • People who want physician-managed dose escalation rather than a fixed dose
  • Patients already on tirzepatide who want to continue at their current dose

Your physician decides whether Tirzepatide is appropriate for you after reviewing your intake and labs.

— Directions & duration

Inject 0.50 mL (50 units) subcutaneously once weekly.

Cycle. Weekly injection. New to it? Dose steps up on a schedule set by your physician; you can request the next step when you're ready. Already on it? Choose your current dose when you order and your physician confirms it at review. Pricing is by dose.
Ready for more? When you're ready, ask your physician to step up to the next dose. Approved steps are charged at the price difference and applied to your next fill.
Directions shown are the pharmacy's standard for this preparation. Your prescription label is the final word.

— What's included

  • Licensed physician review of your intake, history, and labs
  • Medication compounded to your prescription by a PCAB-accredited, FDA-registered pharmacy
  • Every batch independently tested before release
  • Sterile syringes and alcohol prep pads for injectables
  • Tracked delivery to your door, refills on schedule
  • Message your physician anytime; dose changes without an appointment

— Storage & handling

  • Store refrigerated (36–46°F / 2–8°C) at all times, including before first use.
  • One vial is your monthly supply. A fresh vial ships every 28 days on your refill schedule, so you're always well inside the beyond-use date on your label.
  • Protect from light. Wipe the stopper with an alcohol pad before every draw.
  • Dispose of syringes in the sharps container per the included instructions.

— What to expect

A typical course of Tirzepatide.

TimeframeWhat patients commonly report
Weeks 1–4Reduced appetite and earlier fullness are the most common first changes. Mild nausea is common while the body adjusts; for patients new to the medication the starting dose is deliberately low. Already on it? Your provider can continue you at the dose you're on.
Weeks 5–12As the dose steps up under physician direction, weight change typically becomes measurable. Slower is safer.
Month 3 onwardOngoing physician monitoring; long-term results in studies depended on continued treatment alongside diet and activity.
Individual results vary. Compounded medications are not FDA-approved; a licensed physician determines whether treatment is appropriate and monitors your progress.

— The science

How Tirzepatide works, and what the research shows.

— How it works

Tirzepatide is a dual GIP/GLP-1 receptor agonist — it activates both incretin pathways instead of just one.

This dual action produces superior weight loss results vs semaglutide alone.

Phase 3 trials showed up to 22.5% body weight loss.

— Clinical evidence

  • The SURMOUNT-1 trial randomized 2,539 adults with obesity to tirzepatide 5/10/15 mg vs placebo.

    Jastreboff et al., NEJM 2022
  • At 72 weeks, mean weight reductions were 15.0%, 19.5%, and 20.9% on the active arms vs 3.1% on placebo — the highest weight-loss outcomes recorded for a pharmacological intervention at the time.

  • SURMOUNT-2 confirmed efficacy in patients with type 2 diabetes, and the SURPASS program demonstrated superior HbA1c reduction vs semaglutide head-to-head.

    Frias et al., 2021
  • Tirzepatide's dual GIP+GLP-1 mechanism appears to drive both stronger appetite suppression and improved metabolic flexibility.

Full references with PubMed links are listed further down the page.

Tirzepatide (Injectable) vs. Mounjaro / Zepbound

Mounjaro / Zepbound
$1429
per month at brand-name pricing
pepti Tirzepatide (Injectable)
$139
~72% less than brand-name

Compounded at an FDA-registered 503A pharmacy. Compounded medications are not FDA-approved.

References

  1. Jastreboff AM, Aronne LJ, Ahmad NN, et al.. Tirzepatide Once Weekly for the Treatment of Obesity (SURMOUNT-1) · New England Journal of Medicine (2022) · PMID 35658024
  2. Garvey WT, Frias JP, Jastreboff AM, et al.. Tirzepatide once weekly for the treatment of obesity in people with type 2 diabetes (SURMOUNT-2) · Lancet (2023) · PMID 37385275
  3. Frías JP, Davies MJ, Rosenstock J, et al.. Tirzepatide versus Semaglutide Once Weekly in Patients with Type 2 Diabetes (SURPASS-2) · New England Journal of Medicine (2021) · PMID 34170647
  4. Inagaki N, Takeuchi M, Oura T, et al.. Efficacy and safety of tirzepatide monotherapy compared with dulaglutide in Japanese patients with type 2 diabetes (SURPASS J-mono) · The Lancet Diabetes & Endocrinology (2022) · PMID 35468322

Citations are provided for educational purposes. They do not constitute medical advice. Always discuss any peptide protocol with your prescribing physician.

Important safety information

+

Possible side effects

Nausea
Diarrhea or constipation
Fatigue
Reduced appetite
Heartburn

Do not use if you have

Active cancer or history of cancer (unless approved by oncologist)
Pregnancy or breastfeeding
Severe kidney or liver disease
Known allergy to the peptide or excipients
Medullary thyroid cancer history
MEN 2 syndrome

If you experience severe side effects, call 911 or go to your nearest emergency room.

— Common questions

Frequently asked
about Tirzepatide (Injectable).

Mounjaro (diabetes) and Zepbound (weight loss) are Eli Lilly brand-name, FDA-approved products. Our compounded tirzepatide is prepared by an FDA-registered 503A pharmacy and is not FDA-approved — the FDA does not review compounded drugs for safety, effectiveness, or quality. A licensed physician decides whether it's appropriate for you.

— More questions35 more questions about Pepti, answered.

Yes. Tirzepatide is one of the medications Pepti requires recent bloodwork for before it is prescribed. Upload a recent lab report from any lab, or order Pepti's at-home panel; the physician reviews the results with your assessment.

— More from Weight Loss

Pairs well with these.

Get started today

Ready to start with Tirzepatide (Injectable)?

Free assessment. Licensed physicians. Money-back guarantee if not approved.

Money-back guarantee
Free shipping
Cancel anytime
HSA/FSA accepted
Start free assessment
PCAB — Pharmacy Compounding Accreditation Board · Accredited

— Pharmacy network accreditation

PCAB-accredited pharmacies on every order.

Every fulfillment runs through a PCAB-accredited pharmacy.

Rigorous third-party quality & safety inspections
Cleanliness and sterile processes
Proper ingredient sourcing
Accurate dosing and formulation
Staff training and procedures
Accredited by NABP & ACHC
— The pepti app

Total care.
In your pocket.

5.0 on the App Store
Download on the App Store

Free on iOS — Android coming soon

QR code to download the Pepti app on the App StoreScan with your
phone camera
to download
The Pepti app home screen on an iPhone
Important legal & safety information

The assessment process available on the Pepti website asks a series of medical questions, and the answers provided are reviewed by an independent licensed physician affiliated with our partner physician network. The licensed providers have established exclusionary criteria, and the answers provided determine if the individual is screened out of eligibility for treatment. The licensed clinicians retain the sole decision to prescribe peptide therapy and other compounded medications to patients. Treatment may be denied at the physician's sole discretion. If a prescription is not approved, you will not be charged for the medication.

Pharmacy Providers. Pepti is a technology platform and is not a healthcare provider, pharmacy, or prescriber. All medications offered through the platform are compounded by independent FDA-registered 503A or 503B compounding pharmacies based on a valid prescription written by a licensed physician for an individual patient. Compounded medications are not FDA-approved as products. The active pharmaceutical ingredients used by our partner pharmacies are sourced from FDA-registered facilities. Compounded medications may not undergo the same testing or quality control as commercially manufactured FDA-approved drugs.

Results vary. Results from peptide therapy and other compounded treatments vary based on individual factors, including age, weight, medical history, adherence to the prescribed protocol, lifestyle factors, and physiological response. Pepti makes no guarantee of any specific outcome. Statements about peptide therapy and compounded medications offered through the platform have not been evaluated by the Food and Drug Administration. These products are not intended to diagnose, treat, cure, or prevent any disease.

Product images. Product photographs and renderings shown on this website are for illustrative purposes only. The appearance of vials, packaging, labeling, and other materials you receive may vary and is determined by the dispensing compounding pharmacy.

Off-label use.Many peptides offered through the platform are prescribed for off-label use. “Off-label” means the medication is being prescribed for a use, dose, or patient population that is not specifically approved by the FDA. Off-label prescribing is legal and common in U.S. medical practice when supported by clinical experience and judgment.

Mailing & shipping. Pepti currently dispenses prescription medication to patients in all 50 states and Washington, D.C.. All orders ship in unbranded, tamper-evident packaging via expedited delivery from our partner compounding pharmacies. Temperature-sensitive medications ship with insulated packaging and ice packs. Shipping is included at no additional cost. We do not currently ship medication outside all 50 states and Washington, D.C., internationally, or to APO/FPO addresses.

Not for emergencies. Pepti is not designed for medical emergencies. If you are experiencing a medical emergency, call 911 or go to your nearest emergency room immediately. For urgent but non-emergency medical questions, contact your primary care provider or use an urgent care service.

No doctor-patient relationship with Pepti. Your use of the platform does not create a doctor-patient relationship between you and pepti LLC. A doctor-patient relationship is established only between you and the independent licensed physician who reviews your intake and prescribes your treatment. The physicians who use the platform are independent contractors and are solely responsible for the medical care they provide.

Prescription medications. All prescription products require a valid prescription from a licensed healthcare provider. By using the platform, you acknowledge that you are at least 18 years old and that the information you provide is true, accurate, current, and complete. Providing false information may result in inappropriate treatment recommendations or denial of service.

Cosmetic & wellness products.Certain products offered through Pepti — including skincare, hair care, body care, supplements, men's grooming, sports recovery, and sexual wellness products — are cosmetic or dietary supplement products, not prescription medications. These products do not require a prescription and are not reviewed or prescribed by a physician. Statements regarding dietary supplements have not been evaluated by the Food and Drug Administration. These products are not intended to diagnose, treat, cure, or prevent any disease. Results vary by individual. Consult your healthcare provider before starting any new supplement or topical product, especially if you are pregnant, nursing, or taking other medications.

pepti LLC · Delaware Limited Liability Company · 131 Continental Dr, Suite 305, Newark, DE 19713 · For media or partnership inquiries, email hello@hellopepti.com. For patient support, email support@hellopepti.com. For privacy and HIPAA inquiries, email privacy@hellopepti.com.