— Pricing Guide · 2026
How Much Does Semax Cost?
Semax is a synthetic peptide fragment of ACTH, developed in Russia and studied for memory, attention, and BDNF (brain-derived neurotrophic factor) support. It is supplied as a nasal spray. At Pepti, Semax is $269 per monthly fill, all-in: the compounded medication from an FDA-registered US pharmacy, physician review and ongoing care, shipping, and unlimited messaging. There is no membership fee, no consult fee, and no visit fee on top. It ships as a metered nasal spray, so there are no needles or syringes to buy. Nasal formulations cost the pharmacy more per dose than a vial, which is why the sprays sit slightly above the injectable line.
— Insurance
Paying for Semax.
Compounded Semax is a cash-pay prescription and is not covered by insurance or Medicare. HSA and FSA funds can usually be applied.
— Common questions
Semax pricing,
answered.
Semax costs $269 per month at Pepti. That price is all-in — it includes the compounded medication, the licensed physician who reviews your assessment and manages your care, shipping to your door, and unlimited messaging with your care team. Refills are the same price each month; there is no separate membership, consult, or visit fee.
The compounded Semax from an FDA-registered 503A pharmacy, the metered spray bottle, cold-chain shipping, the physician review of your assessment, ongoing physician care and dose adjustments, and unlimited messaging. If the physician does not approve you, the medication charge is refunded.
Yes. Semax is prescription-only. At Pepti you complete a free online assessment, a licensed US physician reviews it, and if it is appropriate for you the prescription is sent to a partner pharmacy that compounds it and ships it to you. Compounded Semax is not FDA-approved; it is prepared to a physician's prescription by a state-licensed, FDA-registered pharmacy.
No. Compounded Semax is a cash-pay prescription and is not covered by insurance or Medicare. Most patients can use HSA or FSA funds, since it is a physician-prescribed medication. Pepti does not bill insurance, which is part of why there are no consult or visit fees.
Research-use-only peptides are sold without a prescription, without a physician, and without a pharmacy. They are labeled "not for human use" for a reason: no one is verifying the identity, purity, sterility, or dose of what is in the vial. Pepti's $269 covers a licensed physician, a state-licensed FDA-registered compounding pharmacy, and independent batch testing for identity, purity, potency, sterility, and endotoxins. You are paying for the medication to be what the label says it is.
Yes. Adding a second medication to the same plan takes 5% off every item, three takes 8% off, and four or more takes 10% off — on every refill, not just the first. A two-medication plan with Semax brings it to $256 per month.
Once per fill. One bottle is your monthly supply, and a fresh one ships about every 28 days depending on the dose your physician prescribes, billed at the same $269 each time. It renews until you cancel, and you can cancel anytime from your account. There is no contract and no cancellation fee.
Most peptide clinics price Semax as a medication fee plus an initial consult, a membership or program fee, and follow-up visit fees, and many require in-person visits. Pepti charges one monthly price of $269 that already includes the physician and shipping, with no consult, membership, or visit fees. Some clinics also dispense research-use-only peptides; Pepti dispenses only physician-prescribed, pharmacy-compounded medication.
— More questions26 more questions about Pepti, answered.
Semax delivered intranasally — studied for memory, focus, neuroprotection, and BDNF support. Semax Nasal Spray is prescription-only at Pepti: a licensed physician reviews your assessment and, if appropriate, prescribes it to be compounded by a state-licensed, FDA-registered pharmacy.
Semax Nasal Spray is $269 per month at Pepti. That is all-in: medication, physician review and ongoing care, shipping, and messaging. No membership, consult, or visit fees, and the price is the same in every state.
Semax Nasal Spray is commonly prescribed for: Adults focused on cognitive performance, focus, and mental stamina; Patients who want a nootropic peptide without a stimulant. Whether it is appropriate for you is decided by the reviewing physician from your history, medications, and labs where required.
Yes. Semax Nasal Spray is prescription-only. The free online assessment takes about five minutes, a physician licensed in your state reviews it within 24 hours, and if approved the prescription goes to the pharmacy. If not approved, the medication charge is refunded.
No. Semax Nasal Spray can be prescribed from the assessment alone. Bloodwork is required only for the GLP-1s and growth-hormone secretagogues, and the intake tells you if a medication on your order needs it.
Semax Nasal Spray is a metered nasal spray, so there are no needles. You use the number of sprays your physician prescribes, on the schedule printed on the pharmacy label.
One bottle is your monthly supply at the dose your physician prescribes. A fresh bottle ships about every 28 days, and the date moves if your physician changes your dose. Store it as the pharmacy label directs.
Once per fill, $269 each time, when the next bottle ships. It renews until you cancel, which you can do anytime from your account with no cancellation fee.
The compounded Semax Nasal Spray, free tracked shipping in an unbranded box, the physician review, ongoing physician care and dose adjustments, and unlimited messaging.
Like any prescription medication, Semax Nasal Spray can have side effects, and the physician screens your history, current medications, and allergies for anything that would make it inappropriate before prescribing. The medication-specific consent lists the known risks, and you can message your physician about anything you notice. Seek emergency care for severe symptoms.
Response varies by person, goal, and dose, and Semax Nasal Spray is prescribed for ongoing use rather than a short trial. Your physician sets expectations at approval, tracks how you respond through your account, and adjusts the dose without an appointment.
Yes. Request it from your account or the app; your physician approves or declines. If approved you pay for the additional medication at the pharmacy's cost and the new dose applies to your next shipment.
Yes. Add Semax Nasal Spray to a plan with another treatment and every medication is 5% off, three are 8% off, and four or more are 10% off, on every refill. The physician reviews the combination and can adjust it.
No. Compounded Semax Nasal Spray is not FDA-approved. It is prepared to your physician's prescription by a state-licensed, FDA-registered 503A pharmacy and every batch is independently tested before release.
Yes, when prescribed by a licensed physician and dispensed by a licensed pharmacy, which is how Pepti provides it in every state it serves. Research-use-only Semax Nasal Spray sold without a prescription is labeled not for human use and is a different product.
Semax is a synthetic fragment of ACTH (amino acids 4-10) with a stabilizing Pro-Gly-Pro tail, developed as a nootropic and neuroprotective agent. At Pepti it is prescribed to support memory & focus, neuroprotection, needle-free nasal mist, bdnf support. Individual response varies, and your physician sets expectations at approval.
Semax is a synthetic fragment of ACTH (amino acids 4-10) with a stabilizing Pro-Gly-Pro tail, developed as a nootropic and neuroprotective agent. It upregulates BDNF — the brain's key growth and plasticity factor — and modulates melanocortin signaling, with effects on attention, memory consolidation, and recovery from neurological stress. Nasal delivery targets the CNS directly. Compounded Semax Nasal Spray is not FDA-approved; it is prescribed off-label by a licensed physician after reviewing your assessment.
Semax Nasal Spray is prescribed for memory & focus, neuroprotection, needle-free nasal mist, bdnf support. It is commonly requested by adults focused on cognitive performance, focus, and mental stamina; patients who want a nootropic peptide without a stimulant. Whether it is appropriate for you is the reviewing physician's decision.
Semax Nasal Spray is studied for memory & focus, neuroprotection, needle-free nasal mist, bdnf support. Those are the goals it is prescribed to support at Pepti; results vary by person, dose, and consistency, and no outcome is guaranteed. Your physician tracks how you respond through your account.
Semax is approved in Russia for stroke recovery and cognitive complaints, supported by Russian clinical trials in stroke, encephalopathy, and attention disorders. As with Selank, that evidence base has not been replicated in Western randomized controlled trials, so US use is investigational and physician-directed. References are listed on this page.
At Pepti. Complete the free assessment, a physician licensed in your state reviews it within 24 hours, and if appropriate Semax Nasal Spray is compounded by a state-licensed, FDA-registered pharmacy and shipped free to your door for $269 per month, all-in. Not prescribed means refunded.
Nasal spray: 20 mL at 2.5 mg/mL, containing 50 mg Semax. One bottle is your monthly supply at the prescribed dose, and a fresh one ships about every 28 days.
Semax Nasal Spray is a nasal spray, so no pen or syringe is involved.
$269 per month covers the compounded Semax Nasal Spray, the physician review, ongoing physician care including dose adjustments and refill review, unlimited messaging, and free tracked shipping. There is no membership, consult, visit, or refill fee; the only separate charges are optional at-home lab panels and a physician-approved dose increase billed at pharmacy cost.
Yes. Semax Nasal Spray is on Pepti's live catalog, which lists only treatments a partner pharmacy can compound and ship today. If a physician prescribes it, it ships; if it ever cannot be dispensed, the charge is refunded.
Semax Nasal Spray ships to all 50 states and Washington, D.C, free and tracked, in insulated unbranded packaging. Eligibility is confirmed during the assessment from your shipping address.
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