ARA-290 (Injectable) in South Dakota
Doctor-prescribed ARA-290 (Injectable) for South Dakota residents. Reviewed by licensed South Dakota physicians, compounded at FDA-registered pharmacies, and shipped to your door.
— All-in monthly price
No membership fee · this is the full price · free shipping · avg 4-week supply
— Add in-depth bloodwork
Optional — add a physician-reviewed at-home blood panel to your plan.
Your sex-hormone baseline plus the safety markers that matter on therapy — blood counts, liver and kidney function — from one painless upper-arm device. Matched to your sex (PSA for men; progesterone & FSH for women). No needle, no clinic, physician-reviewed.
This treatment requires licensed provider review and approval. Treatment is not guaranteed. If prescribed, medication is fulfilled by a licensed U.S. pharmacy where permitted by law. Compounded medications are not FDA-approved or FDA-cleared.
Reviewed
Reviewed by Dr. Gene Lee, MD · Board-certified Family Medicine
Every Pepti prescription is reviewed by a licensed U.S. physician before it's dispensed — and only provided if clinically appropriate.
— The process
How it works in South Dakota
- 1Complete a free online intake (~5 minutes).
- 2A licensed South Dakota physician reviews your case within 24 hours.
- 3Your prescription ships from our FDA-registered compounding pharmacy.
- 4Free shipping arrives 2–4 business days later. Refills ship automatically when your supply runs out — cancel anytime.
— The treatment
What ARA-290 (Injectable) does
ARA-290 is a peptide made from a fragment of erythropoietin, the hormone that protects tissue, and is studied for burning, tingling and numbness from damaged small nerve fibers. It works on the body's repair pathway rather than dulling pain. Compounded; not FDA-approved.
— Formulation
— Quality
Every batch independently tested
Every medication batch dispensed through Pepti is independently tested by a qualified third-party laboratory for applicable quality and safety standards before the pharmacy releases it. Batches are tested to the same standard used by 503B outsourcing facilities.
Sterility
USP <71>Confirms the finished preparation is free of viable microorganisms.
Bacterial endotoxins
USP <85>Screens for endotoxins that can cause fever or inflammatory reactions.
Potency
AssayVerifies the labeled concentration of the active peptide is what is in the vial.
Purity
HPLCChecks the active peptide against impurities and degradation products.
Identity
Mass spectrometryConfirms the peptide in the vial is the correct molecule.
pH
USP <791>Confirms the solution sits within the range specified for injection.
Particulate matter
USP <788>Checks the finished vial for visible and sub-visible particles.
Container closure integrity
USP <1207>Confirms the vial seal holds so sterility is maintained through the beyond-use date.
Telemedicine in South Dakota
South Dakota permits telemedicine prescribing under South Dakota Board of Medical and Osteopathic Examiners rules. A South Dakota-licensed physician can establish the patient relationship through online intake review for non-controlled medications. Pepti is available in all 50 states and Washington, D.C.
South Dakota cities Pepti serves
— Your protocol
How ARA-290 is prescribed in South Dakota.
— Who it's for
- Adults with burning, tingling or numb feet and hands their physician has evaluated
- People with nerve symptoms tied to diabetes, prediabetes or an autoimmune condition
- Patients who want a repair-focused option instead of, or alongside, pain medication
- Someone who tried standard nerve medications and did not tolerate the side effects
Your physician decides whether ARA-290 is appropriate for you after reviewing your intake and labs.
— Directions & duration
Inject 0.25 mL (25 units) subcutaneously once daily Monday through Friday.
— What's included
- Licensed physician review of your intake, history, and labs
- Medication compounded to your prescription by a PCAB-accredited, FDA-registered pharmacy
- Every batch independently tested before release
- Sterile syringes and alcohol prep pads for injectables
- Tracked delivery to your door, refills on schedule
- Message your physician anytime; dose changes without an appointment
— Storage & handling
- Store refrigerated (36–46°F / 2–8°C) at all times, including before first use.
- One vial is your monthly supply. A fresh vial ships to your South Dakota address every 28 days on your refill schedule, so you're always well inside the beyond-use date on your label.
- Protect from light. Wipe the stopper with an alcohol pad before every draw.
- Dispose of syringes in the sharps container per the included instructions.
— What to expect
A typical course of ARA-290 in South Dakota.
— The science
How ARA-290 works, and what the research shows.
— How it works
ARA-290 switches on the body's tissue-repair receptor, the same one erythropoietin uses to protect cells after injury.
Unlike erythropoietin it does not raise red blood cell counts, so it is studied purely for repair, especially of the small nerve fibers behind burning and tingling pain.
— Clinical evidence
Two mid-stage trials in people with small-fiber nerve damage from sarcoidosis reported less neuropathic pain and regrowth of nerve fibers measured in the eye.
Heij and colleagues 2012, Dahan and colleagues 2013Larger late-stage trials have not been completed.
References
- Dahan A, Dunne A, Swartjes M et al.. ARA 290 improves symptoms in patients with sarcoidosis-associated small nerve fiber loss and increases corneal nerve fiber density · Mol Med (2013) · PMID 24136731
- Heij L, Niesters M, Swartjes M et al.. Safety and efficacy of ARA 290 in sarcoidosis patients with symptoms of small fiber neuropathy: a randomized, double-blind pilot study · Mol Med (2012) · PMID 23168581
Citations are provided for educational purposes. They do not constitute medical advice. Always discuss any peptide protocol with your prescribing physician.
— Pharmacy network accreditation
PCAB-accredited pharmacies on every order.
Every fulfillment runs through a PCAB-accredited pharmacy.
— Common questions
Frequently asked
about ARA-290 (Injectable) in South Dakota.
Yes. ARA-290 (Injectable) is legal when prescribed by a physician licensed in South Dakota and dispensed by an FDA-registered compounding pharmacy. South Dakota permits telemedicine prescribing under South Dakota Board of Medical and Osteopathic Examiners rules. A South Dakota-licensed physician can establish the patient relationship through online intake review for non-controlled medications.
Most orders ship from our FDA-registered compounding pharmacy within 1–3 business days after physician approval. Delivery within South Dakota typically arrives 1-3 business days after shipment. Pepti serves patients across South Dakota including Sioux Falls, Rapid City, Aberdeen, and Brookings.
No. Pepti operates as a fully telehealth platform in South Dakota. South Dakota permits telemedicine prescribing under South Dakota Board of Medical and Osteopathic Examiners rules. A South Dakota-licensed physician can establish the patient relationship through online intake review for non-controlled medications.
ARA-290 (Injectable) starts at $219 at Pepti. Pepti is subscription-based — your refill ships when your supply runs out, and you can cancel anytime. Pricing is the same nationwide — no South Dakota-specific markup. Shipping is free.
Yes — Pepti is available in all 50 states and Washington, D.C. Wherever you are in the country, a physician licensed in your state reviews your intake and your medication ships from an FDA-registered compounding pharmacy.
You don't need an in-person peptide clinic — Pepti provides doctor-prescribed ARA-290 (Injectable) entirely online anywhere in South Dakota. A physician licensed in South Dakota reviews your intake, and your medication ships from an FDA-registered compounding pharmacy to your door. Unlike "research use only" peptide sites, every Pepti order requires a valid patient-specific prescription and a licensed dispensing pharmacy.
No. "Research use only" ARA-290 (Injectable) is sold with no prescription, no physician, and no dispensing pharmacy, and is not legally sold for human use — independent testing of research-grade peptides has repeatedly found underdosing, mislabeling, and contamination. Prescription ARA-290 (Injectable) is compounded for you at an FDA-registered US pharmacy after a licensed physician's review. When comparing ARA-290 (Injectable) options in South Dakota, only consider providers that can name their prescribing physicians and their dispensing pharmacy.
— More questions33 more questions about Pepti, answered.
Pepti serves all of South Dakota. A physician licensed in South Dakota reviews every order within 24 hours, the prescription is compounded by a state-licensed, FDA-registered pharmacy, and it ships free and tracked to any South Dakota street address. The price is the same as every other state.
Yes. The whole process is online in South Dakota: a free assessment, physician review, messaging, dose changes, and refills through your Pepti account or the Hello Pepti app. No clinic visit is required.
Pepti ships ARA-290 to South Dakota directly from the pharmacy: free, tracked, unbranded, in insulated packaging with ice packs for refrigerated medication. The pharmacy compounds in 1-3 business days and delivery takes 1-3 business days after shipment. PO Boxes are not accepted.
Every treatment on Pepti's catalog ships to South Dakota. Eligibility is confirmed during the assessment from your South Dakota shipping address, and if anything ever cannot ship to your address it is refunded.
The same as everywhere Pepti serves: one all-in monthly price per treatment that includes the medication, the physician, and shipping, with no South Dakota-specific markup and no membership or consult fee. Every price is on the product page.
Yes. Pepti's physicians hold licenses in South Dakota, and only a physician licensed where you live reviews and prescribes your order. Their names and credentials are on the providers page.
Yes. Pepti's partner pharmacies are state-licensed, FDA-registered 503A compounding pharmacies licensed to dispense into South Dakota, and every batch is independently tested before it ships.
ARA-290 is a peptide made from a fragment of erythropoietin, the hormone that protects tissue, and is studied for burning, tingling and numbness from damaged small nerve fibers. It works on the body's repair pathway rather than dulling pain. Compounded; not FDA-approved. ARA-290 is prescription-only at Pepti: a licensed physician reviews your assessment and, if appropriate, prescribes it to be compounded by a state-licensed, FDA-registered pharmacy.
ARA-290 is commonly prescribed for: Adults with burning, tingling or numb feet and hands their physician has evaluated; People with nerve symptoms tied to diabetes, prediabetes or an autoimmune condition; Patients who want a repair-focused option instead of, or alongside, pain medication; Someone who tried standard nerve medications and did not tolerate the side effects. Whether it is appropriate for you is decided by the reviewing physician from your history, medications, and labs where required.
Yes. ARA-290 is prescription-only. The free online assessment takes about five minutes, a physician licensed in South Dakota reviews it within 24 hours, and if approved the prescription goes to the pharmacy. If not approved, the medication charge is refunded.
No. ARA-290 can be prescribed from the assessment alone. Bloodwork is required only for the GLP-1s and growth-hormone secretagogues, and the intake tells you if a medication on your order needs it.
ARA-290 is a subcutaneous injection into the abdomen or thigh with a small insulin syringe. Your kit ships with sterile syringes and alcohol prep pads, and the exact dose and schedule are printed on the pharmacy label. Dosing videos are in your account.
One vial is your monthly supply at the dose your physician prescribes. A fresh vial ships about every 28 days, and the date moves if your physician changes your dose. Store it as the pharmacy label directs, refrigerated.
Once per fill, $219 each time, when the next vial ships. It renews until you cancel, which you can do anytime from your account with no cancellation fee.
The compounded ARA-290 with sterile syringes and alcohol prep pads, free tracked shipping in an unbranded box with insulated packaging, the physician review, ongoing physician care and dose adjustments, and unlimited messaging.
Reported side effects of ARA-290 are usually mild: mild redness or swelling at injection site; temporary fatigue or headache; mild nausea (uncommon). The physician screens your history, medications, and allergies before prescribing, the medication-specific consent lists the known risks, and you can message your physician about anything you notice. Seek emergency care for severe symptoms.
Response varies by person, goal, and dose, and ARA-290 is prescribed for ongoing use rather than a short trial. Your physician sets expectations at approval, tracks how you respond through your account, and adjusts the dose without an appointment.
Any dose change is made by your physician from the chart, without an appointment. Message them through your account if you think your dose should change.
Yes. Add ARA-290 to a plan with another treatment and both go through one assessment and one physician review, shipping together on one schedule. Each keeps its own catalog price. The physician reviews the combination and can adjust it.
No. Compounded ARA-290 is not FDA-approved. It is prepared to your physician's prescription by a state-licensed, FDA-registered 503A pharmacy and every batch is independently tested before release.
Yes, when prescribed by a licensed physician and dispensed by a licensed pharmacy, which is how Pepti provides it in South Dakota. Research-use-only ARA-290 sold without a prescription is labeled not for human use and is a different product.
ARA-290 switches on the body's tissue-repair receptor, the same one erythropoietin uses to protect cells after injury. At Pepti it is prescribed to support studied for nerve pain and tingling, supports the body's own repair signal, not an opioid, not a sedative, daily injection, monday to friday. Individual response varies, and your physician sets expectations at approval.
ARA-290 switches on the body's tissue-repair receptor, the same one erythropoietin uses to protect cells after injury. Unlike erythropoietin it does not raise red blood cell counts, so it is studied purely for repair, especially of the small nerve fibers behind burning and tingling pain. Compounded ARA-290 is not FDA-approved; it is prescribed off-label by a licensed physician after reviewing your assessment.
ARA-290 is prescribed for studied for nerve pain and tingling, supports the body's own repair signal, not an opioid, not a sedative, daily injection, monday to friday. It is commonly requested by adults with burning, tingling or numb feet and hands their physician has evaluated; people with nerve symptoms tied to diabetes, prediabetes or an autoimmune condition; patients who want a repair-focused option instead of, or alongside, pain medication; Someone who tried standard nerve medications and did not tolerate the side effects. Whether it is appropriate for you is the reviewing physician's decision.
ARA-290 is studied for studied for nerve pain and tingling, supports the body's own repair signal, not an opioid, not a sedative, daily injection, monday to friday. Those are the goals it is prescribed to support at Pepti; results vary by person, dose, and consistency, and no outcome is guaranteed. Your physician tracks how you respond through your account.
Two mid-stage trials in people with small-fiber nerve damage from sarcoidosis (Heij and colleagues 2012, Dahan and colleagues 2013) reported less neuropathic pain and regrowth of nerve fibers measured in the eye. Larger late-stage trials have not been completed. References are listed on this page.
ARA-290 is generally not prescribed with: active cancer or history of cancer (unless approved by oncologist); pregnancy or breastfeeding; severe kidney or liver disease; known allergy to the peptide or excipients. The physician screens for these in your intake, and anything that rules ARA-290 out means it is not prescribed and is refunded.
At Pepti. Complete the free assessment, a physician licensed in South Dakota reviews it within 24 hours, and if appropriate ARA-290 is compounded by a state-licensed, FDA-registered pharmacy and shipped free to your door for $219 per month, all-in. Not prescribed means refunded.
Injectable vial: 5 mL at 2 mg/mL, containing 10 mg ARA-290. One vial is your monthly supply at the prescribed dose, and a fresh one ships about every 28 days.
Not currently. ARA-290 ships as a multi-dose vial with sterile syringes and prep pads. The pepti Pen is available for 10 other treatments.
$219 per month covers the compounded ARA-290, the physician review, ongoing physician care including dose adjustments and refill review, unlimited messaging, and free tracked shipping. There is no membership, consult, visit, or refill fee; the only separate charges are optional at-home lab panels and a physician-approved dose increase billed at pharmacy cost.
Yes. ARA-290 is on Pepti's live catalog, which lists only treatments a partner pharmacy can compound and ship today. If a physician prescribes it, it ships; if it ever cannot be dispensed, the charge is refunded.
ARA-290 ships to all 50 states and Washington, D.C, free and tracked, in insulated unbranded packaging. Eligibility is confirmed during the assessment from your shipping address.
ARA-290 (Injectable) in every state
Pepti is available in all 50 states and Washington, D.C.
Pepti operates in South Dakota through licensed physician partnerships. Compounded medications are produced at FDA-registered 503A pharmacies. Treatment decisions are made by your prescribing physician.