— Pricing Guide · 2026
How Much Does TB-500 Cost?
TB-500 is a synthetic fragment of Thymosin Beta-4, a naturally occurring protein involved in cell migration and tissue repair. It is studied for systemic recovery support, flexibility, and slow-healing soft-tissue injuries. At Pepti, TB-500 is $249 per monthly fill, all-in: the compounded medication from an FDA-registered US pharmacy, physician review and ongoing care, shipping, and unlimited messaging. There is no membership fee, no consult fee, and no visit fee on top. It ships as a multi-dose vial with sterile syringes and alcohol prep pads included.
— Insurance
Paying for TB-500.
Compounded TB-500 is a cash-pay prescription and is not covered by insurance or Medicare. HSA and FSA funds can usually be applied.
— Common questions
TB-500 pricing,
answered.
TB-500 costs $249 per month at Pepti. That price is all-in — it includes the compounded medication, the licensed physician who reviews your assessment and manages your care, shipping to your door, and unlimited messaging with your care team. Refills are the same price each month; there is no separate membership, consult, or visit fee.
The compounded TB-500 from an FDA-registered 503A pharmacy, the vial with sterile syringes and alcohol prep pads, cold-chain shipping, the physician review of your assessment, ongoing physician care and dose adjustments, and unlimited messaging. If the physician does not approve you, the medication charge is refunded.
Yes. TB-500 is prescription-only. At Pepti you complete a free online assessment, a licensed US physician reviews it, and if it is appropriate for you the prescription is sent to a partner pharmacy that compounds it and ships it to you. Compounded TB-500 is not FDA-approved; it is prepared to a physician's prescription by a state-licensed, FDA-registered pharmacy.
No. Compounded TB-500 is a cash-pay prescription and is not covered by insurance or Medicare. Most patients can use HSA or FSA funds, since it is a physician-prescribed medication. Pepti does not bill insurance, which is part of why there are no consult or visit fees.
Research-use-only peptides are sold without a prescription, without a physician, and without a pharmacy. They are labeled "not for human use" for a reason: no one is verifying the identity, purity, sterility, or dose of what is in the vial. Pepti's $249 covers a licensed physician, a state-licensed FDA-registered compounding pharmacy, and independent batch testing for identity, purity, potency, sterility, and endotoxins. You are paying for the medication to be what the label says it is.
Yes. Adding a second medication to the same plan takes 5% off every item, three takes 8% off, and four or more takes 10% off — on every refill, not just the first. A two-medication plan with TB-500 brings it to $237 per month.
Once per fill. One vial is your monthly supply, and a fresh one ships about every 28 days depending on the dose your physician prescribes, billed at the same $249 each time. It renews until you cancel, and you can cancel anytime from your account. There is no contract and no cancellation fee.
Most peptide clinics price TB-500 as a medication fee plus an initial consult, a membership or program fee, and follow-up visit fees, and many require in-person visits. Pepti charges one monthly price of $249 that already includes the physician and shipping, with no consult, membership, or visit fees. Some clinics also dispense research-use-only peptides; Pepti dispenses only physician-prescribed, pharmacy-compounded medication.
— More questions26 more questions about Pepti, answered.
Thymosin Beta-4 promotes cell migration and tissue repair at a systemic level. TB-500 is prescription-only at Pepti: a licensed physician reviews your assessment and, if appropriate, prescribes it to be compounded by a state-licensed, FDA-registered pharmacy.
TB-500 is $249 per month at Pepti. That is all-in: medication, physician review and ongoing care, shipping, and messaging. No membership, consult, or visit fees, and the price is the same in every state.
TB-500 is commonly prescribed for: Adults with soft-tissue injuries or slow-healing strains; Patients seeking support for flexibility and range of motion during rehab; Athletes and active adults managing recurring overuse injuries. Whether it is appropriate for you is decided by the reviewing physician from your history, medications, and labs where required.
Yes. TB-500 is prescription-only. The free online assessment takes about five minutes, a physician licensed in your state reviews it within 24 hours, and if approved the prescription goes to the pharmacy. If not approved, the medication charge is refunded.
No. TB-500 can be prescribed from the assessment alone. Bloodwork is required only for the GLP-1s and growth-hormone secretagogues, and the intake tells you if a medication on your order needs it.
TB-500 is a subcutaneous injection into the abdomen or thigh with a small insulin syringe. Your kit ships with sterile syringes and alcohol prep pads, and the exact dose and schedule are printed on the pharmacy label. Dosing videos are in your account.
One vial is your monthly supply at the dose your physician prescribes. A fresh vial ships about every 28 days, and the date moves if your physician changes your dose. Store it as the pharmacy label directs, refrigerated.
The compounded TB-500 with sterile syringes and alcohol prep pads, free tracked shipping in an unbranded box with insulated packaging, the physician review, ongoing physician care and dose adjustments, and unlimited messaging.
Reported side effects of TB-500 are usually mild: mild redness or swelling at injection site; temporary fatigue or headache; mild nausea (uncommon). The physician screens your history, medications, and allergies before prescribing, the medication-specific consent lists the known risks, and you can message your physician about anything you notice. Seek emergency care for severe symptoms.
Response varies by person, goal, and dose, and TB-500 is prescribed for ongoing use rather than a short trial. Your physician sets expectations at approval, tracks how you respond through your account, and adjusts the dose without an appointment.
Yes. Request it from your account or the app; your physician approves or declines. If approved you pay for the additional medication at the pharmacy's cost and the new dose applies to your next shipment.
Yes. Add TB-500 to a plan with another treatment and every medication is 5% off, three are 8% off, and four or more are 10% off, on every refill. The physician reviews the combination and can adjust it.
No. Compounded TB-500 is not FDA-approved. It is prepared to your physician's prescription by a state-licensed, FDA-registered 503A pharmacy and every batch is independently tested before release.
Yes, when prescribed by a licensed physician and dispensed by a licensed pharmacy, which is how Pepti provides it in every state it serves. Research-use-only TB-500 sold without a prescription is labeled not for human use and is a different product.
Thymosin Beta-4 (TB-500) is a 43-amino-acid peptide that promotes cell migration, differentiation, and tissue repair at a systemic level. At Pepti it is prescribed to support tissue repair, flexibility, reduced scarring, wound healing. Individual response varies, and your physician sets expectations at approval.
Thymosin Beta-4 (TB-500) is a 43-amino-acid peptide that promotes cell migration, differentiation, and tissue repair at a systemic level. It works by binding to actin, supporting wound healing throughout the body — not just at one site. Compounded TB-500 is not FDA-approved; it is prescribed off-label by a licensed physician after reviewing your assessment.
TB-500 is prescribed for tissue repair, flexibility, reduced scarring, wound healing. It is commonly requested by adults with soft-tissue injuries or slow-healing strains; patients seeking support for flexibility and range of motion during rehab; Athletes and active adults managing recurring overuse injuries. Whether it is appropriate for you is the reviewing physician's decision.
TB-500 is studied for tissue repair, flexibility, reduced scarring, wound healing. Those are the goals it is prescribed to support at Pepti; results vary by person, dose, and consistency, and no outcome is guaranteed. Your physician tracks how you respond through your account.
Thymosin Beta-4's tissue-repair biology is well characterized: it promoted cardiac cell migration and survival after injury in influential animal work (Bock-Marquette et al., Nature 2004) and supports corneal and dermal wound healing in preclinical models. Synthetic Tβ4 has reached human trials for wound healing and eye conditions with encouraging safety but limited efficacy data. TB-500, the widely used fragment of Tβ4, has not itself been through human clinical trials. References are listed on this page.
TB-500 is generally not prescribed with: active cancer or history of cancer (unless approved by oncologist); pregnancy or breastfeeding; severe kidney or liver disease; known allergy to the peptide or excipients. The physician screens for these in your intake, and anything that rules TB-500 out means it is not prescribed and is refunded.
At Pepti. Complete the free assessment, a physician licensed in your state reviews it within 24 hours, and if appropriate TB-500 is compounded by a state-licensed, FDA-registered pharmacy and shipped free to your door for $249 per month, all-in. Not prescribed means refunded.
Injectable vial: 5 mL at 3 mg/mL, containing 15 mg TB-500. One vial is your monthly supply at the prescribed dose, and a fresh one ships about every 28 days.
Not currently. TB-500 ships as a multi-dose vial with sterile syringes and prep pads. The pepti Pen is available for 10 other treatments.
$249 per month covers the compounded TB-500, the physician review, ongoing physician care including dose adjustments and refill review, unlimited messaging, and free tracked shipping. There is no membership, consult, visit, or refill fee; the only separate charges are optional at-home lab panels and a physician-approved dose increase billed at pharmacy cost.
Yes. TB-500 is on Pepti's live catalog, which lists only treatments a partner pharmacy can compound and ship today. If a physician prescribes it, it ships; if it ever cannot be dispensed, the charge is refunded.
TB-500 ships to all 50 states and Washington, D.C, free and tracked, in insulated unbranded packaging. Eligibility is confirmed during the assessment from your shipping address.
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