— Pricing Guide · 2026
How Much Does Tirzepatide Cost?
Tirzepatide (brand names Mounjaro and Zepbound) is currently the most-effective approved GLP-1 weight loss medication, producing up to 22.5% body weight reduction in clinical trials. Brand pricing exceeds $1,400/month without insurance. Compounded tirzepatide from FDA-registered pharmacies costs significantly less. This page covers current 2026 pricing, including how compounded options compare to brand prices and what you should expect with and without insurance.
Tirzepatide price by dose
New to tirzepatide? You start at the starter dose. Already on it? Choose your current dose when you order and your physician confirms it at review. Every price is all-in and monthly.
- 2.5mgstarter dose$139/mo
- 5mg$165/mo
- 7.5mg$170/mo
- 10mg$196/mo
- 12.5mg$217/mo
- 15mg$243/mo
Brand-name pricing
Competitor pricing
- Ro (Roman)Lower starter dose pricing.$299
- Henry Meds$369
- Mochi Health$399
— Insurance
Paying for Tirzepatide.
Brand-name Zepbound is FDA-approved for weight loss and covered by some plans with prior authorization. Compounded tirzepatide is typically not covered. HSA/FSA usually applies.
— Common questions
Tirzepatide pricing,
answered.
Mounjaro and Zepbound are brand-name, FDA-approved products. Compounded tirzepatide is prepared by an FDA-registered 503A compounding pharmacy and is not FDA-approved — the FDA does not review compounded drugs for safety, effectiveness, or quality. Cost is typically 70%+ lower.
Yes — in head-to-head trials (SURPASS-2), tirzepatide produced ~6% more weight loss than semaglutide at maximum doses. The dual GIP+GLP-1 mechanism appears to drive stronger appetite suppression and metabolic effects.
Yes — your price includes physician review, dose titration, and direct messaging. No separate consult fees, and you can cancel anytime.
No. When you order, choose the dose you're currently on and your physician can continue you there after reviewing your intake. Each dose has its own all-in monthly price, listed above — from $139 at the starter dose.
Dual GIP and GLP-1 receptor agonist offering enhanced weight management benefits. Tirzepatide is prescription-only at Pepti: a licensed physician reviews your assessment and, if appropriate, prescribes it to be compounded by a state-licensed, FDA-registered pharmacy.
Tirzepatide is $139 per month at Pepti. That is all-in: medication, physician review and ongoing care, shipping, and messaging. No membership, consult, or visit fees, and the price is the same in every state.
— More questions25 more questions about Pepti, answered.
Tirzepatide is commonly prescribed for: Adults with a BMI in the range their physician considers appropriate for dual GIP/GLP-1 therapy; Patients who did not reach their goal on semaglutide; People who want physician-managed dose escalation rather than a fixed dose; Patients already on tirzepatide who want to continue at their current dose. Whether it is appropriate for you is decided by the reviewing physician from your history, medications, and labs where required.
Yes. Tirzepatide is prescription-only. The free online assessment takes about five minutes, a physician licensed in your state reviews it within 24 hours, and if approved the prescription goes to the pharmacy. If not approved, the medication charge is refunded.
Yes. Tirzepatide is one of the medications Pepti requires recent bloodwork for before it is prescribed. Upload a recent lab report from any lab, or order Pepti's at-home panel; the physician reviews the results with your assessment.
Tirzepatide is a subcutaneous injection into the abdomen or thigh with a small insulin syringe. Your kit ships with sterile syringes and alcohol prep pads, and the exact dose and schedule are printed on the pharmacy label. Dosing videos are in your account.
One vial is your monthly supply at the dose your physician prescribes. A fresh vial ships about every 28 days, and the date moves if your physician changes your dose. Store it as the pharmacy label directs, refrigerated.
Once per fill, $139 each time, when the next vial ships. It renews until you cancel, which you can do anytime from your account with no cancellation fee.
The compounded Tirzepatide with sterile syringes and alcohol prep pads, free tracked shipping in an unbranded box with insulated packaging, the physician review, ongoing physician care and dose adjustments, and unlimited messaging.
Reported side effects of Tirzepatide are usually mild: nausea; diarrhea or constipation; fatigue; reduced appetite; heartburn. The physician screens your history, medications, and allergies before prescribing, the medication-specific consent lists the known risks, and you can message your physician about anything you notice. Seek emergency care for severe symptoms.
Response varies by person, goal, and dose, and Tirzepatide is prescribed for ongoing use rather than a short trial. Your physician sets expectations at approval, tracks how you respond through your account, and adjusts the dose without an appointment.
Yes, one step at a time. Tirzepatide moves up the pharmacy's strength ladder when your physician approves, and you pay the cost difference for the higher strength. It is never doubled.
Yes. Add Tirzepatide to a plan with another treatment and every medication is 5% off, three are 8% off, and four or more are 10% off, on every refill. The physician reviews the combination and can adjust it.
Compounded Tirzepatide is not FDA-approved. A brand-name form of the active ingredient is FDA-approved for specific indications; Pepti's version is compounded to your physician's prescription by an FDA-registered 503A pharmacy and prescribed off-label.
Yes, when prescribed by a licensed physician and dispensed by a licensed pharmacy, which is how Pepti provides it in every state it serves. Research-use-only Tirzepatide sold without a prescription is labeled not for human use and is a different product.
Tirzepatide is a dual GIP/GLP-1 receptor agonist — it activates both incretin pathways instead of just one. At Pepti it is prescribed to support dual gip/glp-1 action, superior weight loss, metabolic health, appetite reduction. Individual response varies, and your physician sets expectations at approval.
Tirzepatide is a dual GIP/GLP-1 receptor agonist — it activates both incretin pathways instead of just one. This dual action produces superior weight loss results vs semaglutide alone. Phase 3 trials showed up to 22.5% body weight loss. Compounded Tirzepatide is not FDA-approved; it is prescribed off-label by a licensed physician after reviewing your assessment.
Tirzepatide is prescribed for dual gip/glp-1 action, superior weight loss, metabolic health, appetite reduction. It is commonly requested by adults with a BMI in the range their physician considers appropriate for dual GIP/GLP-1 therapy; patients who did not reach their goal on semaglutide; people who want physician-managed dose escalation rather than a fixed dose; patients already on tirzepatide who want to continue at their current dose. Whether it is appropriate for you is the reviewing physician's decision.
Tirzepatide is studied for dual gip/glp-1 action, superior weight loss, metabolic health, appetite reduction. Those are the goals it is prescribed to support at Pepti; results vary by person, dose, and consistency, and no outcome is guaranteed. Your physician tracks how you respond through your account.
The SURMOUNT-1 trial (Jastreboff et al., NEJM 2022) randomized 2,539 adults with obesity to tirzepatide 5/10/15 mg vs placebo. At 72 weeks, mean weight reductions were 15.0%, 19.5%, and 20.9% on the active arms vs 3.1% on placebo — the highest weight-loss outcomes recorded for a pharmacological intervention at the time. SURMOUNT-2 confirmed efficacy in patients with type 2 diabetes, and the SURPASS program (Frias et al., 2021) demonstrated superior HbA1c reduction vs semaglutide head-to-head. Tirzepatide's dual GIP+GLP-1 mechanism appears to drive both stronger appetite suppression and improved metabolic flexibility. References are listed on this page.
Tirzepatide is generally not prescribed with: active cancer or history of cancer (unless approved by oncologist); pregnancy or breastfeeding; severe kidney or liver disease; known allergy to the peptide or excipients; medullary thyroid cancer history; men 2 syndrome. The physician screens for these in your intake, and anything that rules Tirzepatide out means it is not prescribed and is refunded.
At Pepti. Complete the free assessment, a physician licensed in your state reviews it within 24 hours, and if appropriate Tirzepatide is compounded by a state-licensed, FDA-registered pharmacy and shipped free to your door for $139 per month, all-in. Not prescribed means refunded.
Injectable vial: 2 mL, containing compounded to your dose Tirzepatide + included Pyridoxine (B6). One vial is your monthly supply at the prescribed dose, and a fresh one ships about every 28 days.
Not currently. Tirzepatide ships as a multi-dose vial with sterile syringes and prep pads. The pepti Pen is available for 10 other treatments.
$139 per month covers the compounded Tirzepatide, the physician review, ongoing physician care including dose adjustments and refill review, unlimited messaging, and free tracked shipping. There is no membership, consult, visit, or refill fee; the only separate charges are optional at-home lab panels and a physician-approved dose increase billed at pharmacy cost.
Yes. Tirzepatide is on Pepti's live catalog, which lists only treatments a partner pharmacy can compound and ship today. If a physician prescribes it, it ships; if it ever cannot be dispensed, the charge is refunded.
Tirzepatide ships to all 50 states and Washington, D.C, free and tracked, in insulated unbranded packaging. Eligibility is confirmed during the assessment from your shipping address.
Ready to start with Tirzepatide?
Free intake review by a licensed physician. Medication refunded if not approved.
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