— Pricing Guide · 2026
How Much Does PT-141 Cost?
PT-141 (bremelanotide) is a melanocortin-receptor agonist that acts centrally rather than on blood flow. Its brand-name form, Vyleesi, is FDA-approved for hypoactive sexual desire disorder in premenopausal women; compounded PT-141 is prescribed off-label for adults of any sex. At Pepti, PT-141 is $259 per monthly fill, all-in: the compounded medication from an FDA-registered US pharmacy, physician review and ongoing care, shipping, and unlimited messaging. There is no membership fee, no consult fee, and no visit fee on top. It is available as a standard vial for $259 or as a pre-filled pepti Pen for $319; the injector pen itself is included free with your first pen order. PT-141 is dosed as needed rather than daily, so one vial typically lasts longer than a month.
— Insurance
Paying for PT-141.
Compounded PT-141 is a cash-pay prescription and is not covered by insurance or Medicare. HSA and FSA funds can usually be applied.
— Common questions
PT-141 pricing,
answered.
PT-141 costs $259 per month at Pepti as a vial, or $319 as a pre-filled pepti Pen. That price is all-in — it includes the compounded medication, the licensed physician who reviews your assessment and manages your care, shipping to your door, and unlimited messaging with your care team. Refills are the same price each month; there is no separate membership, consult, or visit fee.
The compounded PT-141 from an FDA-registered 503A pharmacy, the vial with sterile syringes and alcohol prep pads, cold-chain shipping, the physician review of your assessment, ongoing physician care and dose adjustments, and unlimited messaging. If the physician does not approve you, the medication charge is refunded.
Yes. PT-141 is prescription-only. At Pepti you complete a free online assessment, a licensed US physician reviews it, and if it is appropriate for you the prescription is sent to a partner pharmacy that compounds it and ships it to you. Compounded PT-141 is not FDA-approved; it is prepared to a physician's prescription by a state-licensed, FDA-registered pharmacy.
No. Compounded PT-141 is a cash-pay prescription and is not covered by insurance or Medicare. Most patients can use HSA or FSA funds, since it is a physician-prescribed medication. Pepti does not bill insurance, which is part of why there are no consult or visit fees.
Research-use-only peptides are sold without a prescription, without a physician, and without a pharmacy. They are labeled "not for human use" for a reason: no one is verifying the identity, purity, sterility, or dose of what is in the vial. Pepti's $259 covers a licensed physician, a state-licensed FDA-registered compounding pharmacy, and independent batch testing for identity, purity, potency, sterility, and endotoxins. You are paying for the medication to be what the label says it is.
Yes. Adding a second medication to the same plan takes 5% off every item, three takes 8% off, and four or more takes 10% off — on every refill, not just the first. A two-medication plan with PT-141 brings it to $246 per month.
Once per fill. One vial is your monthly supply, and a fresh one ships about every 28 days depending on the dose your physician prescribes, billed at the same $259 each time. It renews until you cancel, and you can cancel anytime from your account. There is no contract and no cancellation fee.
Most peptide clinics price PT-141 as a medication fee plus an initial consult, a membership or program fee, and follow-up visit fees, and many require in-person visits. Pepti charges one monthly price of $259 that already includes the physician and shipping, with no consult, membership, or visit fees. Some clinics also dispense research-use-only peptides; Pepti dispenses only physician-prescribed, pharmacy-compounded medication.
— More questions26 more questions about Pepti, answered.
Bremelanotide activates melanocortin receptors in the brain to support sexual desire and function. PT-141 is prescription-only at Pepti: a licensed physician reviews your assessment and, if appropriate, prescribes it to be compounded by a state-licensed, FDA-registered pharmacy.
PT-141 is $259 per month at Pepti as a vial, or $319 as a pre-filled pepti Pen. That is all-in: medication, physician review and ongoing care, shipping, and messaging. No membership, consult, or visit fees, and the price is the same in every state.
PT-141 is commonly prescribed for: Adults experiencing low libido or arousal difficulty; Patients for whom PDE5 medications are not appropriate or not enough; Men and women; PT-141 acts centrally rather than on blood flow. Whether it is appropriate for you is decided by the reviewing physician from your history, medications, and labs where required.
Yes. PT-141 is prescription-only. The free online assessment takes about five minutes, a physician licensed in your state reviews it within 24 hours, and if approved the prescription goes to the pharmacy. If not approved, the medication charge is refunded.
No. PT-141 can be prescribed from the assessment alone. Bloodwork is required only for the GLP-1s and growth-hormone secretagogues, and the intake tells you if a medication on your order needs it.
PT-141 is a subcutaneous injection into the abdomen or thigh with a small insulin syringe. Your kit ships with sterile syringes and alcohol prep pads, and the exact dose and schedule are printed on the pharmacy label. Dosing videos are in your account. It is also available as a pre-filled pepti Pen for $319.
One vial is your monthly supply at the dose your physician prescribes. A fresh vial ships about every 28 days, and the date moves if your physician changes your dose. Store it as the pharmacy label directs, refrigerated.
The compounded PT-141 with sterile syringes and alcohol prep pads, free tracked shipping in an unbranded box with insulated packaging, the physician review, ongoing physician care and dose adjustments, and unlimited messaging.
Reported side effects of PT-141 are usually mild: mild nausea (most common); temporary flushing; slight headache; increase in blood pressure (transient). The physician screens your history, medications, and allergies before prescribing, the medication-specific consent lists the known risks, and you can message your physician about anything you notice. Seek emergency care for severe symptoms.
Response varies by person, goal, and dose, and PT-141 is prescribed for ongoing use rather than a short trial. Your physician sets expectations at approval, tracks how you respond through your account, and adjusts the dose without an appointment.
Any dose change is made by your physician from the chart, without an appointment. Message them through your account if you think your dose should change.
Yes. Add PT-141 to a plan with another treatment and every medication is 5% off, three are 8% off, and four or more are 10% off, on every refill. The physician reviews the combination and can adjust it.
Compounded PT-141 is not FDA-approved. A brand-name form of the active ingredient is FDA-approved for specific indications; Pepti's version is compounded to your physician's prescription by an FDA-registered 503A pharmacy and prescribed off-label.
Yes, when prescribed by a licensed physician and dispensed by a licensed pharmacy, which is how Pepti provides it in every state it serves. Research-use-only PT-141 sold without a prescription is labeled not for human use and is a different product.
PT-141 (Bremelanotide) activates melanocortin-4 receptors in the brain. At Pepti it is prescribed to support enhanced desire, improved performance, doctor-supervised, free shipping. Individual response varies, and your physician sets expectations at approval.
PT-141 (Bremelanotide) activates melanocortin-4 receptors in the brain. Unlike Viagra/Cialis (which work on blood flow), PT-141 works on the central nervous system to enhance desire. Effective for both men and women. Compounded PT-141 is not FDA-approved; it is prescribed off-label by a licensed physician after reviewing your assessment.
PT-141 is prescribed for enhanced desire, improved performance, doctor-supervised, free shipping. It is commonly requested by adults experiencing low libido or arousal difficulty; patients for whom PDE5 medications are not appropriate or not enough; Men and women; PT-141 acts centrally rather than on blood flow. Whether it is appropriate for you is the reviewing physician's decision.
PT-141 is studied for enhanced desire, improved performance, doctor-supervised, free shipping. Those are the goals it is prescribed to support at Pepti; results vary by person, dose, and consistency, and no outcome is guaranteed. Your physician tracks how you respond through your account.
PT-141 (bremelanotide) was FDA-approved in 2019 under the brand Vyleesi for hypoactive sexual desire disorder (HSDD) in premenopausal women. The RECONNECT trials (Kingsberg et al., Obstet Gynecol 2019) showed statistically significant improvements in desire and reductions in distress vs placebo. Earlier studies in men with erectile dysfunction (Diamond et al., J Sex Med 2006) showed efficacy distinct from PDE5 inhibitors — PT-141 works centrally on melanocortin pathways rather than peripherally on vasodilation, making it useful in patients who don't respond to Viagra or Cialis or whose primary concern is desire rather than erectile function. References are listed on this page.
PT-141 is generally not prescribed with: active cancer or history of cancer (unless approved by oncologist); pregnancy or breastfeeding; severe kidney or liver disease; known allergy to the peptide or excipients; uncontrolled hypertension; cardiovascular disease. The physician screens for these in your intake, and anything that rules PT-141 out means it is not prescribed and is refunded.
At Pepti. Complete the free assessment, a physician licensed in your state reviews it within 24 hours, and if appropriate PT-141 is compounded by a state-licensed, FDA-registered pharmacy and shipped free to your door for $259 per month, all-in. Not prescribed means refunded.
Injectable vial: 5 mL at 10 mg/mL, containing 50 mg PT-141 (Bremelanotide). Pepti Pen cartridge: 3 mL cartridge (300 units), containing 10 mg PT-141 (Bremelanotide). One vial is your monthly supply at the prescribed dose, and a fresh one ships about every 28 days.
Yes. PT-141 is available as a pre-filled pepti Pen cartridge for $319 per month, versus $259 as a vial. Same medication, same pharmacy; the reusable injector is free with your first pen order. Choose the format in the cart or ask your physician.
$259 per month covers the compounded PT-141, the physician review, ongoing physician care including dose adjustments and refill review, unlimited messaging, and free tracked shipping. There is no membership, consult, visit, or refill fee; the only separate charges are optional at-home lab panels and a physician-approved dose increase billed at pharmacy cost.
Yes. PT-141 is on Pepti's live catalog, which lists only treatments a partner pharmacy can compound and ship today. If a physician prescribes it, it ships; if it ever cannot be dispensed, the charge is refunded.
PT-141 ships to all 50 states and Washington, D.C, free and tracked, in insulated unbranded packaging. Eligibility is confirmed during the assessment from your shipping address.
Ready to start with PT-141?
Free intake review by a licensed physician. Medication refunded if not approved.
Start free assessment
