— Pricing Guide · 2026
How Much Does MOTS-c Cost?
MOTS-c is a mitochondrial-derived peptide encoded in mitochondrial DNA. It is studied for metabolic regulation, insulin sensitivity, and cellular energy in adults. At Pepti, MOTS-c is $259 per monthly fill, all-in: the compounded medication from an FDA-registered US pharmacy, physician review and ongoing care, shipping, and unlimited messaging. There is no membership fee, no consult fee, and no visit fee on top. It is available as a standard vial for $259 or as a pre-filled pepti Pen for $339; the injector pen itself is included free with your first pen order.
— Insurance
Paying for MOTS-c.
Compounded MOTS-c is a cash-pay prescription and is not covered by insurance or Medicare. HSA and FSA funds can usually be applied.
— Common questions
MOTS-c pricing,
answered.
MOTS-c costs $259 per month at Pepti as a vial, or $339 as a pre-filled pepti Pen. That price is all-in — it includes the compounded medication, the licensed physician who reviews your assessment and manages your care, shipping to your door, and unlimited messaging with your care team. Refills are the same price each month; there is no separate membership, consult, or visit fee.
The compounded MOTS-c from an FDA-registered 503A pharmacy, the vial with sterile syringes and alcohol prep pads, cold-chain shipping, the physician review of your assessment, ongoing physician care and dose adjustments, and unlimited messaging. If the physician does not approve you, the medication charge is refunded.
Yes. MOTS-c is prescription-only. At Pepti you complete a free online assessment, a licensed US physician reviews it, and if it is appropriate for you the prescription is sent to a partner pharmacy that compounds it and ships it to you. Compounded MOTS-c is not FDA-approved; it is prepared to a physician's prescription by a state-licensed, FDA-registered pharmacy.
No. Compounded MOTS-c is a cash-pay prescription and is not covered by insurance or Medicare. Most patients can use HSA or FSA funds, since it is a physician-prescribed medication. Pepti does not bill insurance, which is part of why there are no consult or visit fees.
Research-use-only peptides are sold without a prescription, without a physician, and without a pharmacy. They are labeled "not for human use" for a reason: no one is verifying the identity, purity, sterility, or dose of what is in the vial. Pepti's $259 covers a licensed physician, a state-licensed FDA-registered compounding pharmacy, and independent batch testing for identity, purity, potency, sterility, and endotoxins. You are paying for the medication to be what the label says it is.
Yes. Adding a second medication to the same plan takes 5% off every item, three takes 8% off, and four or more takes 10% off — on every refill, not just the first. A two-medication plan with MOTS-c brings it to $246 per month.
Once per fill. One vial is your monthly supply, and a fresh one ships about every 28 days depending on the dose your physician prescribes, billed at the same $259 each time. It renews until you cancel, and you can cancel anytime from your account. There is no contract and no cancellation fee.
Most peptide clinics price MOTS-c as a medication fee plus an initial consult, a membership or program fee, and follow-up visit fees, and many require in-person visits. Pepti charges one monthly price of $259 that already includes the physician and shipping, with no consult, membership, or visit fees. Some clinics also dispense research-use-only peptides; Pepti dispenses only physician-prescribed, pharmacy-compounded medication.
— More questions26 more questions about Pepti, answered.
A mitochondrial-derived peptide that regulates metabolic homeostasis and cellular energy. MOTS-c is prescription-only at Pepti: a licensed physician reviews your assessment and, if appropriate, prescribes it to be compounded by a state-licensed, FDA-registered pharmacy.
MOTS-c is $259 per month at Pepti as a vial, or $339 as a pre-filled pepti Pen. That is all-in: medication, physician review and ongoing care, shipping, and messaging. No membership, consult, or visit fees, and the price is the same in every state.
MOTS-c is commonly prescribed for: Adults focused on metabolic health, endurance, and insulin sensitivity; Patients who want a mitochondrial-targeting peptide alongside training. Whether it is appropriate for you is decided by the reviewing physician from your history, medications, and labs where required.
Yes. MOTS-c is prescription-only. The free online assessment takes about five minutes, a physician licensed in your state reviews it within 24 hours, and if approved the prescription goes to the pharmacy. If not approved, the medication charge is refunded.
No. MOTS-c can be prescribed from the assessment alone. Bloodwork is required only for the GLP-1s and growth-hormone secretagogues, and the intake tells you if a medication on your order needs it.
MOTS-c is a subcutaneous injection into the abdomen or thigh with a small insulin syringe. Your kit ships with sterile syringes and alcohol prep pads, and the exact dose and schedule are printed on the pharmacy label. Dosing videos are in your account. It is also available as a pre-filled pepti Pen for $339.
One vial is your monthly supply at the dose your physician prescribes. A fresh vial ships about every 28 days, and the date moves if your physician changes your dose. Store it as the pharmacy label directs, refrigerated.
The compounded MOTS-c with sterile syringes and alcohol prep pads, free tracked shipping in an unbranded box with insulated packaging, the physician review, ongoing physician care and dose adjustments, and unlimited messaging.
Reported side effects of MOTS-c are usually mild: mild redness or swelling at injection site; temporary fatigue or headache; mild nausea (uncommon). The physician screens your history, medications, and allergies before prescribing, the medication-specific consent lists the known risks, and you can message your physician about anything you notice. Seek emergency care for severe symptoms.
Response varies by person, goal, and dose, and MOTS-c is prescribed for ongoing use rather than a short trial. Your physician sets expectations at approval, tracks how you respond through your account, and adjusts the dose without an appointment.
Yes. Request it from your account or the app; your physician approves or declines. If approved you pay for the additional medication at the pharmacy's cost and the new dose applies to your next shipment.
Yes. Add MOTS-c to a plan with another treatment and every medication is 5% off, three are 8% off, and four or more are 10% off, on every refill. The physician reviews the combination and can adjust it.
No. Compounded MOTS-c is not FDA-approved. It is prepared to your physician's prescription by a state-licensed, FDA-registered 503A pharmacy and every batch is independently tested before release.
Yes, when prescribed by a licensed physician and dispensed by a licensed pharmacy, which is how Pepti provides it in every state it serves. Research-use-only MOTS-c sold without a prescription is labeled not for human use and is a different product.
MOTS-c is a peptide encoded within mitochondrial DNA. At Pepti it is prescribed to support mitochondrial health, metabolic regulation, exercise mimetic, longevity. Individual response varies, and your physician sets expectations at approval.
MOTS-c is a peptide encoded within mitochondrial DNA. It regulates metabolic homeostasis, improves insulin sensitivity, and acts as an exercise mimetic — boosting cellular energy and metabolic flexibility. Compounded MOTS-c is not FDA-approved; it is prescribed off-label by a licensed physician after reviewing your assessment.
MOTS-c is prescribed for mitochondrial health, metabolic regulation, exercise mimetic, longevity. It is commonly requested by adults focused on metabolic health, endurance, and insulin sensitivity; patients who want a mitochondrial-targeting peptide alongside training. Whether it is appropriate for you is the reviewing physician's decision.
MOTS-c is studied for mitochondrial health, metabolic regulation, exercise mimetic, longevity. Those are the goals it is prescribed to support at Pepti; results vary by person, dose, and consistency, and no outcome is guaranteed. Your physician tracks how you respond through your account.
MOTS-c was identified as a mitochondrial-derived peptide regulating metabolic homeostasis, where it improved insulin sensitivity and exercise capacity in mice (Lee et al., Cell Metab 2015). Levels rise with exercise in humans, and an analog has entered early-phase human trials for metabolic disease. Direct human outcome data for MOTS-c itself remains limited — it is prescribed as an investigational metabolic peptide. References are listed on this page.
MOTS-c is generally not prescribed with: active cancer or history of cancer (unless approved by oncologist); pregnancy or breastfeeding; severe kidney or liver disease; known allergy to the peptide or excipients. The physician screens for these in your intake, and anything that rules MOTS-c out means it is not prescribed and is refunded.
At Pepti. Complete the free assessment, a physician licensed in your state reviews it within 24 hours, and if appropriate MOTS-c is compounded by a state-licensed, FDA-registered pharmacy and shipped free to your door for $259 per month, all-in. Not prescribed means refunded.
Injectable vial: 5 mL at 2 mg/mL, containing 10 mg MOTS-c. Pepti Pen cartridge: 3 mL cartridge (300 units) at 10 mg/mL, containing 30 mg MOTS-c. One vial is your monthly supply at the prescribed dose, and a fresh one ships about every 28 days.
Yes. MOTS-c is available as a pre-filled pepti Pen cartridge for $339 per month, versus $259 as a vial. Same medication, same pharmacy; the reusable injector is free with your first pen order. Choose the format in the cart or ask your physician.
$259 per month covers the compounded MOTS-c, the physician review, ongoing physician care including dose adjustments and refill review, unlimited messaging, and free tracked shipping. There is no membership, consult, visit, or refill fee; the only separate charges are optional at-home lab panels and a physician-approved dose increase billed at pharmacy cost.
Yes. MOTS-c is on Pepti's live catalog, which lists only treatments a partner pharmacy can compound and ship today. If a physician prescribes it, it ships; if it ever cannot be dispensed, the charge is refunded.
MOTS-c ships to all 50 states and Washington, D.C, free and tracked, in insulated unbranded packaging. Eligibility is confirmed during the assessment from your shipping address.
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